Devices, methods, and systems are provided for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment. A video-assisted thoracoscopic device is inserted into a thoracic cavity of a patient and positioned at a fissure between a target lung compartment and an adjacent lung compartment. A collateral flow channel between the target lung compartment and the adjacent lung compartment is then identified using the video-assisted thoracoscopic device and an agent is injected into the collateral flow channel, thereby reducing the collateral flow channel.

The present invention provides for a method for the treatment of a respiratory disease, disorder or condition, or a viral infection or viral disease, disorder or condition in a subject, the method comprising the step of administering to said subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises niclosamide or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device.

A method of delivering a therapeutic agent to a nucleus pulposus of an intervertebral disc is provided. The method comprises inserting a delivery tool containing the therapeutic agent through an anterior portion, a lateral portion, or an anterolateral portion of an annulus fibrosus and into the nucleus pulposus of the intervertebral disc; and delivering the therapeutic agent to the nucleus pulposus of the intervertebral disc. Devices and kits are also provided.

A system for delivering a composition containing a nutritional supplement matrix to a user through the oral mucosa, in which the matrix is held under pressure in a canister that has a nozzle with at least one rotating internal member positioned between the canister outlet and the nozzle outlet, in which the rotating member agitates the composition to increase atomization to aid in absorption.

A system for delivering a composition containing a nutritional supplement matrix to a user through the oral mucosa, in which the matrix is held under pressure in a canister that has a nozzle with at least one rotating internal member positioned between the canister outlet and the nozzle outlet, in which the rotating member agitates the composition to increase atomization to aid in absorption.

Provided is pharmaceutical composition for intranasal delivery, wherein the pharmaceutical composition includes a therapeutically active ingredient including a CGRP inhibitor. Also provided is a method for delivering a CGRP inhibitor to a subject, wherein the method includes intranasally administering to the subject a composition including a therapeutically active component including a CGRP inhibitor.

A computer-based system for receiving, analyzing, processing, managing and sending personal health information, and other information in conjunction with use of one or more personal nebulizer or vaporizing devices and personal breath analysis devices. System devices include a personal nebulizer or vaporizing unit with a mouthpiece, which may be detachable and replaceable. The mouthpiece includes an orifice through which vapor is emitted. The substance to be vaporized is contained in an ampoule inserted into the device, where the substance enters an atomization chamber where vaporization is achieved through piezoelectric transducers or atomizers providing sonic or ultrasonic vibration. The substance includes a variety of therapeutic, homeopathic, or naturopathic formulations, remedies, or serums.

A method of peritoneal removal of electrolytes and inflammatory mediators. The method begins with infusing a treatment solution into the peritoneal cavity of a patient by way of a catheter. The treatment solution is drained from the peritoneal cavity by way of the catheter. During the draining, the treatment solution is filtered for removing electrolytes and inflammatory mediators.

An electronic device for producing an aerosol for inhalation by a person includes a mouthpiece located at one of opposite longitudinal ends of the device; a liquid container; a transducer that, when actuated, causes a liquid from the container to be aerosolized such that the aerosol may be inhaled from the device by a person through the mouthpiece; and circuitry and a power supply for actuating the transducer. The mouthpiece, the container, and the transducer are located in-line along a longitudinal axis of a housing of the device extending between the opposite longitudinal ends of the device. The container is located between and separates the transducer and the mouthpiece. The container and the transducer are contained within a cartridge that is insertable into and removable from the housing of the device. The container and the transducer are replaceable by the person when the liquid in the container is depleted.

A vaporizer cartridge of an inhaler has a liquid storage tank and a hollow body with a continuous air flow channel. The storage tank has an access opening to the air flow channel. A vaporizer unit extends over the entire access opening and is arranged in the region of the access opening. The vaporizer unit has a wick member towards the storage tank and a heating member towards the air flow channel. The vaporizer unit is liquid-permeable such that liquid is conveyed at least initially from the tank through the vaporizer unit to the channel in a capillary manner. The interior of the tank is structurally divided into fluidically coupled main and auxiliary volume. Only the auxiliary volume is in direct contact with the vaporizer unit, such that the liquid from the main volume contacts the wick member solely via the auxiliary volume. An inhaler may include the vaporizer cartridge.