A method of generating a focused shock wave with a handheld focused extracorporeal shock wave therapy (f-ESWT) device includes driving a plurality of piezoelectric elements to generate a focused shock wave based on a first plurality of time delays when a first standoff structure is removably connected to a handheld housing of the f-ESWT device, and driving the plurality of piezoelectric elements to generate the focused shock wave based on a second plurality of time delays when a second standoff structure is removably connected to the handheld housing of the f-ESWT device, the second plurality of time delays different from the first plurality of time delays, and the second standoff structure different from the first standoff structure.

A treatment method to reduce or eliminate a patient's symptoms caused by a medical condition or disease is disclosed. The treatment has the step of administering acoustic shock waves directed to one or more reflexology zones or to one or more reflexology zones and an area near a source of the pain if any is exhibited to treat the medical condition. The treatment further has the steps of activating acoustic shock waves of an acoustic shock wave generator to emit acoustic shock waves and subjecting the one or more reflexology zones or the one or more reflexology zones and the area near a source of the medical condition or pain, if any is exhibited, to acoustic shock waves to treat the medical condition.

Embodiments of the present disclosure are directed to methods of inducing therapeutic adipose tissue inflammation using high frequency pressure waves (e.g. high frequency shockwaves) wherein the inflammation results in a reduction in the volume of subcutaneous adipose tissue. Embodiments include applying electrohydraulic generated shockwaves at a rate of between 10 Hz and 1000 Hz to reduce the appearance of cellulite or the volume of subcutaneous fat in a treatment area.

A histotripsy therapy system configured for the treatment of brain tissue is provided, which may include any number of features. In one embodiment, the system includes an ultrasound therapy transducer, a drainage catheter, and a plurality of piezoelectric sensors disposed in the drainage catheter. The ultrasound therapy is configured to transmit ultrasound pulses into the brain to generate cavitation that liquefies a target tissue in the brain. The drainage catheter is configured to detect the ultrasound pulses. An aberration correction algorithm can be executed by the system based on the ultrasound pulses measured by the drainage catheter to automatically correct for an aberration effect caused by the ultrasound pulses passing through a skullcap of the patient.

A transducer array includes at least one annular shear wave generation transducer that defines an interior area, the at least one annular shear wave generation transducer being configured to generate a shear wave excitation to a region of interest such that the shear wave excitation excites at least a part of a corresponding cylindrical portion of the region of interest and shear waves propagating from the cylindrical portion of the region of interest constructively interfere in an interior region of the cylindrical portion of the region of interest: and at least one tracking transducer positioned in the interior area of the at least one annular shear wave generation transducer, the at least one tracking transducer being configured to detect a shear wave in the interior region of the region of interest.

Disclosed are devices suitable for treatment of subcutaneous tissue by transdermally-inducing ultrasonic vibrations in subcutaneous tissue and/or transdermally delivering energy with electromagnetic radiation such as light to subcutaneous tissue. In some embodiments, the treatment of subcutaneous tissue is effective in reducing the amount of subcutaneous fat therein. In some embodiments, transdermal radiation-delivery of energy and transdermal induction of ultrasonic vibrations in subcutaneous tissue can be performed simultaneously, alternatingly or in an unrelated fashion. In some embodiments, the device simultaneously transdermally-induces both ultrasonic transverse and ultrasonic longitudinal vibrations in subcutaneous tissue.

Embodiments of the inventive concept provide an ultrasonic medical instrument moving horizontally by adjusting a depth wise location of an ultrasonic wave generating unit while not influencing an internal volume of a cartridge and variously setting focusing depths of ultrasonic waves in skin.

An ultrasound system is disclosed that utilizes an arbitrary waveform generator, memory, and an ultrasound transducer. A plurality of excitation waveforms are stored in the memory and may be output from the arbitrary waveform generator to an ultrasound transducer. At least one first excitation waveform is stored in the memory and includes an excitation portion with no damping portion (e.g., for one ultrasound procedure; such that an output from the ultrasound transducer is of a first bandwidth). At least one second excitation waveform is stored in the memory and includes an excitation portion and a damping portion (e.g., for another ultrasound procedure; such that an output from the ultrasound transducer is of a second bandwidth that is larger than the first bandwidth).

Shockwaves or modulated pressure waves are applied to targeted lung tissue of humans or animals, including lung tissue having a viral or bacterial infection or a chronic lung condition, to destroy or render innocuous different pathogens and treat the underlying chronic or acute medical conditions.

A therapy apparatus for treating tissue by the emission of focused ultrasound waves, including:

a creation surface of a pressure field of focused ultrasound waves divided into at least N sectors having segments of asymmetrical concave curve (S1, S2, . . . ) with centres of curvature;

centres of curvature (c.sub.1, c.sub.2, . . . ) asymmetrical to the extent where the centres of curvature are situated at different distances from the plane of symmetry (A1) or from the axis of symmetry (S) and/or at different depths taken according to the axis of symmetry;

the individual axes (a.sub.1, a.sub.2, . . . ) intersecting between the focal zones (Zc.sub.1, Zc.sub.2, . . . ) and the creation surface (8) or beyond the focal zones such that the beams originating from the sectors intersect to create a focal coverage zone (Zr) which is off-axis relative to the plane of symmetry (A1) or to the axis of symmetry (S);

the sectors of this creation surface (8) creating energy deposit zones with profiles corresponding to the focal coverage zones (Zr).