A histotripsy therapy system configured for the treatment of brain tissue is provided, which may include any number of features. In one embodiment, the system includes an ultrasound therapy transducer, a drainage catheter, and a plurality of piezoelectric sensors disposed in the drainage catheter. The ultrasound therapy is configured to transmit ultrasound pulses into the brain to generate cavitation that liquefies a target tissue in the brain. The drainage catheter is configured to detect the ultrasound pulses. An aberration correction algorithm can be executed by the system based on the ultrasound pulses measured by the drainage catheter to automatically correct for an aberration effect caused by the ultrasound pulses passing through a skullcap of the patient.

Systems and methods for treating cancer and for preventing metastasis using low intensity focused ultrasound in combination with an anti-cancer therapy are disclosed.

The present invention relates to a portable HIFU skin care device. The portable HIFU skin care device (1) of the present invention is divided into three portions. Firstly, a main body (100) has a rechargeable battery embedded therein, a power button and a step button installed therein for adjusting the intensity of an ultrasonic wave, and a display for displaying the operation states of the device, including the number of shots. In addition, a cartridge (200) is used by being mounted on a head part of the main body (100) and has a HIFU transducer embedded therein. A cradle (300) has a charging part which is installed therein, is capable of charging by being connected with the cartridge (200) and an adaptor, accommodates the main body (100) through a placement groove while the cartridge (200) is mounted to the main body (100), includes a UV lamp for disinfecting the head part of the cartridge (200) when accommodating the main body (100), and charges an internal battery of the main body (100). In an operation state, while the HIFU transducer is linearly moved for each one shot by a piezoelectric motor, a plurality of ultrasonic waves are emitted so as to form a plurality of ultrasonic focal point regions on an object, thereby achieving a skin care effect. In the present invention, the piezoelectric motor (216) is particularly installed inside the cartridge (200).

A method for treating a nerve within a treatment region includes identifying the treatment region and positioning a device on a surface of skin for emitting ultrasound energy, wherein the device comprises a transducer array. The method further includes focusing the transducer array within the positioned device such that the ultrasound energy is focused on the treatment region, and verifying the positioned device is directing ultrasound energy on the treatment region. The method also includes delivering ultrasound energy to the treatment region based on a predetermined time, and removing the positioned device when the predetermined time has been reached.

Various approaches for focusing an ultrasound transducer having multiple transducer elements include causing the transducer elements to transmit ultrasound waves to a target region and measure reflections of the ultrasound waves off the target region; for each of at least some of the transducer elements, adjusting a parameter value associated with said each transducer element based at least in part on parameter values associated with multiple measuring transducer elements weighted by signal quality metrics associated with the reflections measured by the measuring transducer elements so as to improve an ultrasound focus at the target region.

This application relates to a transmitting/receiving dual-mode focused ultrasonic transducer and a microbubble cavitation image visualization method using the transducer. In one aspect, a plurality of mounting holes are formed in a transducer body with a limited area according to the Fibonacci pattern that allows for the maximum number of objects to be mounted in the transducer body. A plurality of transducer elements are mounted in the mounting holes so as to form a transducer element arrangement having highly nonlinearity. According to various embodiments, microbubble cavitation can be induced and visualized by using a small number of receiving elements.

This application relates to a multi-channel ultrasound stimulator. The ultrasound stimulator includes a housing with a concavely curved inner surface and a plurality of channels disposed on the inner surface and spaced from each other at regular intervals. Each of the channels can emit ultrasonic waves independently of each other, and the channels form a wide ultrasound field range. The channels are arranged in a zigzag pattern. The channels can generate an ultrasound field to uniformly stimulate breast tissue of a patient due to the arrangement thereof on the concavely curved surface. A rotator rotates the housing about a rotary shaft to increase an application range of ultrasonic waves and to prevent local concentration of application of ultrasonic waves. A controller operates the channels according to a predetermined operation sequence according to the intensity of ultrasonic waves of each channel, thereby preventing excessive stimulation and enabling uniform stimulation.

An ultrasonic diagnosis and therapy apparatus according to an embodiment may include an ultrasound output unit including a plurality of ultrasound output elements, a circuit board that can be attached and detached through a connecting board connected to the ultrasound output unit to determine a function of the ultrasound output unit, and a control unit configured to control a setting value of each of the plurality of ultrasound output elements, wherein therapy and diagnosis functions are selectively or simultaneously implemented by changing the circuit board. With the ultrasonic diagnosis and therapy apparatus, it is possible to selectively or simultaneously implement the therapy and diagnosis functions by selectively mounting different types of circuit boards that determine the type and function of ultrasound outputted from the ultrasonic transducers.

A multi-pillar piezoelectric stack (MPPS) ultrasound transducer includes N pillars, each formed of a stack of M piezoelectric elements, N and M being integers of at least two. The ultrasound transducer further includes a bonding layer between each pair of the M piezoelectric elements. The pillars are laterally spaced from each other to form an inter-pillar gap. The transducer further includes at least one electrical interconnect for connecting the ultrasound transducer to a signal source. Through the MPPS design, the therapeutic range and the transducer sensitivity are increased over the conventional single pillar piezoelectric stack (SPPS) transducer design.

Systems and methods for treating cancer and for preventing metastasis using low intensity focused ultrasound in combination with an anti-cancer therapy are disclosed.