A catheter system for ablation of tissue around a blood vessel, e.g., the pulmonary artery, to reduce neural activity of nerves surrounding the blood vessel. The catheter system includes an elongate shaft having a proximal portion coupled to a handle, and a distal portion. The distal portion includes a transducer and an expandable anchor, which may be actuated to transition between a collapsed delivery state and an expanded deployed state where the anchor centralizes the transducer within the blood vessel. The transducer may be actuated to emit energy to reduce neural activity of the nerves surrounding the blood vessel. Systems and method are further provided for confirming that neural activity of the nerves surround the blood vessel has been sufficiently reduced.

A stereotactic frame includes a vertical column that extends up from a base. A first laterally extending support arm extends from a first side of the column and a second laterally extending support arm extends from a second side of the column. One of the first or second support arms may include a transducer assembly. The transducer assembly may move a focal point of the transducer in different lateral and longitudinal horizontal positions and different vertical positions. The transducer assembly also may move the focal point of the transducer beam into different pivoting angled positions. The stereotactic frame applies repeatable ultrasonic energy to targets inside a patient without using invasive attachment procedures and without having to repeatedly use expensive magnetic resonance imaging (MRI) machines.

The present invention relates to a low-intensity focused ultrasound therapeutic device. According to one aspect of the present invention, provided is a low-intensity focused ultrasound therapeutic device which employs a single element ultrasound transducer having a focal region, a focal distance and output intensity that can be provide safer treatment for the deep brain of a patient.

Ultrasonic energy is used for treating degenerative dementia. A focal point of an ultrasonic transducer beam is directed at a target area of the brain to promote removal of substances that accumulate in the interstitial pathways that are at least partially responsible for the degenerative dementia. In one example, the target area of the brain may comprise the hippocampus and the degenerative dementia may be Alzheimer's disease. The ultrasonic beam may stimulate brain tissue at a frequency that corresponds to a naturally occurring deep sleep burst frequency of neurons and subsequent astrocyte activation patterns that drive a convective process responsible for brain solute disposal. For example, the transducer may generate a burst frequency of between 1-4 hertz to stimulate deep sleep brain functions that help remove amyloid plaque.

Embodiments herein provide an ultrasonic treatment device that includes a transducer holder to hold an ultrasonic transducer. The transducer holder includes multiple mounting positions for the ultrasonic transducer to enable the transducer to be held by the transducer holder at different angles. For example, in some embodiments, the transducer holder may include multiple mounting elements on an interior surface of the transducer holder. The mounting elements may be, for example, ridges or grooves on the interior surface. The transducer may include and/or be provided with one or more locking elements that interact with the mounting elements of the transducer holder to hold the transducer within the transducer holder. Other embodiments may be described and claimed.

Ultrasonic energy is used for treating degenerative dementia. A focal point of an ultrasonic transducer beam is directed at a target area of the brain to promote removal of substances that accumulate in the interstitial pathways that are at least partially responsible for the degenerative dementia. In one example, the target area of the brain may comprise the hippocampus and the degenerative dementia may be Alzheimer's disease. The ultrasonic beam may stimulate brain tissue at a frequency that corresponds to a naturally occurring deep sleep burst frequency of neurons and subsequent astrocyte activation patterns that drive a convective process responsible for brain solute disposal. For example, the transducer may generate a burst frequency of between 1-4 hertz to stimulate deep sleep brain functions that help remove amyloid plaque.

The present disclosure provides an extracorporeal focused ultrasound treatment device for a pelvic disease. The treatment device includes an ultrasonic transducer and a treatment couch. Sound emitting surface of the ultrasonic transducer is a spherical surface having a first notch, a second notch and a third notch, the first notch and the second notch are respectively positioned at two intersections of the spherical surface and a diameter perpendicular to the main great circle, and the third notch connects the first notch with the second notch; a cross-section of the sound emitting surface parallel to the main great circle is in a shape of an arc; and an ultrasonic wave generated by the sound generation unit is focused at a center of the sphere corresponding to the sound emitting surface. The treatment couch is configured for a human body to lie in a lithotomy position.

Embodiments herein provide an ultrasonic treatment device that includes a transducer holder to hold an ultrasonic transducer. The transducer holder includes multiple mounting positions for the ultrasonic transducer to enable the transducer to be held by the transducer holder at different angles. For example, in some embodiments, the transducer holder may include multiple mounting elements on an interior surface of the transducer holder. The mounting elements may be, for example, ridges or grooves on the interior surface. The transducer may include and/or be provided with one or more locking elements that interact with the mounting elements of the transducer holder to hold the transducer within the transducer holder. Other embodiments may be described and claimed.

The present invention relates to a therapeutic ultrasonic wave generating device. The present invention includes: a rotating motor; an ultrasonic wave generating unit being provided with a transducer generating ultrasonic waves; and a focus rotation movement unit moving the focus of the ultrasonic waves generated by the ultrasonic wave generating unit in a circle on the same plane by receiving a transmission of rotational force of the rotating motor. The present invention enables: the focus of ultrasonic waves to be moved in the circle having a constant radius at a uniform depth under the skin; and energy to be applied uniformly and evenly within the movement radius, thereby enabling enhancement of therapeutic performance.

An apparatus for controlling the angular direction of energy emitted from a plurality of energy delivery devices. The apparatus includes a plurality of rods, each rod mechanically coupled to one of the energy delivery devices, to a stationary plate, and to a moveable plate. The stationary plate includes holes that are configured to receive a portion of a first rotatable joint that is mechanically coupled to each rod. The moveable plate includes holes that are configured to receive a portion of a second rotatable joint, the second rotatable joint slidingly engaging a portion of the respective rod. The angle of each rod changes when the moveable plate is moved in any direction with respect to the stationary plate. Changing the rod angle changes the angular direction of the energy emitted from the energy delivery devices such that the energy passes through an intended focal position.