G01N33/48

METHOD FOR IDENTIFYING CELL HAVING SPECIFIC BIOLOGICAL CHARACTERISTICS BY CELL CLASSIFICATION PROCESS AND APPLICATION METHOD THEREOF

The present invention relates to a method for identifying a cell (group), a method comprising a cell stratifying process utilizing quantitative physical property data, a method for separating a cell (group) utilizing the cell stratifying process, a method for identifying a molecular marker that identifies a cell (group) utilizing the cell stratifying process, a method for culturing a cell (group) utilizing the cell stratifying process, a program for causing a computer to execute a step of identifying a cell (group) utilizing the cell stratifying process, and a system for analyzing, identifying, or separating a cell (group) utilizing the cell stratifying process.

CAPILLARY BLOOD COLLECTING DEVICE
20230041849 · 2023-02-09 ·

The present disclosure relates to a capillary blood collecting device which includes a fixing device including an accommodating cavity for accommodating a blood collection finger and a squeezing member for squeezing blood to a fingertip site. The capillary blood collecting device is configured to detachably accommodate at least one skin puncture part on a blood collection side of the finger, and the skin puncture part includes a blood lancet that may be driven to puncture the blood collection finger, such that a sufficient amount of capillary blood quickly flows out from the capillary blood converged at the fingertip under the action of blood lancet.

CAPILLARY BLOOD COLLECTING DEVICE
20230041849 · 2023-02-09 ·

The present disclosure relates to a capillary blood collecting device which includes a fixing device including an accommodating cavity for accommodating a blood collection finger and a squeezing member for squeezing blood to a fingertip site. The capillary blood collecting device is configured to detachably accommodate at least one skin puncture part on a blood collection side of the finger, and the skin puncture part includes a blood lancet that may be driven to puncture the blood collection finger, such that a sufficient amount of capillary blood quickly flows out from the capillary blood converged at the fingertip under the action of blood lancet.

Predictive test for prognosis of myelodysplastic syndrome patients using mass spectrometry of blood-based sample

A method of predicting whether an MDS patient has a good or poor prognosis uses a general purpose computer configured as a classifier and mass-spectrometry data obtained from a blood-based sample. The classifier assigns a classification label of either Early or Late (or the equivalent) to the patient's sample. Patients classified as Early are predicted to have a poor prognosis or worse survival whereas those patients classified as Late are predicted to have a relatively better prognosis and longer survival time. The groupings demonstrated a large effect size between groups in Kaplan-Meier analysis of survival. Most importantly, while the classifications generated were correlated with other prognostic factors, such as IPSS score and genetic category, multivariate and subgroup analysis showed that they had significant independent prognostic power complementary to the existing prognostic factors.

APPARATUS AND METHOD FOR MEASURING PRESENCE OF ORGANIC MATTER OR LIFE/DEATH OF LIVING MATTER

This invention relates to an apparatus and a method for measuring whether organic matter is present or whether or not organisms (cells or tissue) are alive using infrared absorption spectroscopic analysis. The measurement apparatus of the invention includes an infrared light source for radiating infrared rays on a sample, an infrared detection unit for detecting the infrared rays transmitted or reflected from the sample, and a determination unit for identifying an amide infrared absorption peak of the sample using the detected infrared rays and for determining whether organic matter is present or whether organisms are alive or not in the sample using the identified amide infrared absorption peak. In this invention, a reagent is not used, simple measurement is performed, quantification is feasible, and the presence or absence of cells or tissues and changes in the life and death can be consecutively measured for the same sample.

APPARATUS AND METHOD FOR MEASURING PRESENCE OF ORGANIC MATTER OR LIFE/DEATH OF LIVING MATTER

This invention relates to an apparatus and a method for measuring whether organic matter is present or whether or not organisms (cells or tissue) are alive using infrared absorption spectroscopic analysis. The measurement apparatus of the invention includes an infrared light source for radiating infrared rays on a sample, an infrared detection unit for detecting the infrared rays transmitted or reflected from the sample, and a determination unit for identifying an amide infrared absorption peak of the sample using the detected infrared rays and for determining whether organic matter is present or whether organisms are alive or not in the sample using the identified amide infrared absorption peak. In this invention, a reagent is not used, simple measurement is performed, quantification is feasible, and the presence or absence of cells or tissues and changes in the life and death can be consecutively measured for the same sample.

DEVICE AND METHOD FOR SINGLE CELL SCREENING BASED ON INTER-CELLULAR COMMUNICATION

A device for single-cell analysis according to an embodiment of the present invention comprises: a substrate; a gap between the substrate and porous membrane which is a space for culture medium; and a porous membrane formed on having a pore capable of isolating a second cell into single cell units.

A method for single-cell analysis according to an embodiment of the present invention comprises: Culturing a first cell in a culture medium on a bottom side of porous membrane; Applying a sample including a second cell on a porous membrane in a culture medium; Isolating the second cell into single cell units in a pore existing in the porous membrane with a external force such as agitation and gravitational force; Generating an interaction situation between the first cells and the single cell-level second cell; Analyzing a cellular phenomena of the first cell or the second cell.

DEVICE AND METHOD FOR SINGLE CELL SCREENING BASED ON INTER-CELLULAR COMMUNICATION

A device for single-cell analysis according to an embodiment of the present invention comprises: a substrate; a gap between the substrate and porous membrane which is a space for culture medium; and a porous membrane formed on having a pore capable of isolating a second cell into single cell units.

A method for single-cell analysis according to an embodiment of the present invention comprises: Culturing a first cell in a culture medium on a bottom side of porous membrane; Applying a sample including a second cell on a porous membrane in a culture medium; Isolating the second cell into single cell units in a pore existing in the porous membrane with a external force such as agitation and gravitational force; Generating an interaction situation between the first cells and the single cell-level second cell; Analyzing a cellular phenomena of the first cell or the second cell.

KIT FOR DETECTING VIRUS

The present invention relates to a kit for detecting a virus, a composition for detecting a virus and a method for detecting a virus. According to the present invention, viruses may be detected with high efficiency at low cost within a short period of time.

PHOSPHOR-INTEGRATED NANOPARTICLES USED IN FLUORESCENCE OBSERVATION
20180011086 · 2018-01-11 ·

The present invention may provide phosphor-integrated nanoparticles whose precipitation and/or aggregation, particularly aggregation can be inhibited upon carrying out immunostaining therewith and which can thus be used for staining even after long-term storage without requiring a complicated operation, the phosphor-integrated nanoparticles preferrably maintaining excellent performance, such as staining properties, even after long-term storage. The phosphor-integrated nanoparticles of the present invention have an average sphericity (f) of 0.80 to 0.95 and preferably have an average circumference ratio (R) of 0.50 to 0.95. More preferably, the matrix of the particles contains an organic compound, the phosphor-integrated nanoparticles have an average particle size of 300 nm or less, and a biological component-binding molecule is bound on the particle