To provide a sensor device and a measurement apparatus that are able to appropriately control a temperature of a sensing region where a potential is measured. Provided is a sensor device that includes an electrode array exposed to a sensing region, at least one or more wiring line layers provided in a layer same as the electrode array, a temperature determiner that determines a temperature of the sensing region on the basis of an electric resistance of the wiring line layer, and a temperature controller that controls the temperature of the sensing region on the basis of the temperature of the sensing region determined by the temperature determiner.

Certain embodiments are directed hydrophilic redox substrates for leukocyte esterase (LE). In certain aspects a hydrophilic redox leukocyte esterase substrate or a small molecule enzyme substrate for use in methods and/or devices to electrochemically detect and/or measure LE activity in a sample.

Certain embodiments are directed hydrophilic redox substrates for leukocyte esterase (LE). In certain aspects a hydrophilic redox leukocyte esterase substrate or a small molecule enzyme substrate for use in methods and/or devices to electrochemically detect and/or measure LE activity in a sample.

Various embodiments of the present disclosure are directed to carbon dioxide and/or hydrogen sulphide sampling and detection system and method for determination of the content of gaseous CO2 and/or H2S in a liquid, among other chemical compounds. In one embodiment, the detection system includes a membrane block having a liquid sample inlet port and a sample outlet port between which a sample flow path extends. The membrane block includes a first membrane unit and a second membrane unit. The first membrane unit includes a sample flow on the first side of a first permeable membrane element, and a carrier gas flow on the second side of the first permeable membrane element. The second membrane unit having a sample flow on the first side of a second permeable membrane element and a carrier gas flow on the second side of the second permeable membrane element.

Various embodiments of the present disclosure are directed to carbon dioxide and/or hydrogen sulphide sampling and detection system and method for determination of the content of gaseous CO2 and/or H2S in a liquid, among other chemical compounds. In one embodiment, the detection system includes a membrane block having a liquid sample inlet port and a sample outlet port between which a sample flow path extends. The membrane block includes a first membrane unit and a second membrane unit. The first membrane unit includes a sample flow on the first side of a first permeable membrane element, and a carrier gas flow on the second side of the first permeable membrane element. The second membrane unit having a sample flow on the first side of a second permeable membrane element and a carrier gas flow on the second side of the second permeable membrane element.

NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P).sup.+) or derivative thereof; an NAD(P).sup.+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.

A multi-sensor system may include a catheter that has lumen, is flexible, is made of a polymer, and has a circular cross section that has an outer diameter of no more than 0.5 cm; and one or more sensors that sense multiple characteristics of material flowing within the lumen, including at least two of the following: flow rate, pressure, and composition of the material. A multi-sensor system may include a catheter that has lumen, is flexible, is made of a polymer, and has a circular cross section that has an outer diameter of no more than 0.5 cm; and one or more sensors that sense multiple characteristics of material flowing within the lumen, including at least two of the following: flow rate, pressure, and composition of the material.

Provided is an electrolyte analysis device capable of suppressing a burden with respect to measurement while suppressing a decrease in accuracy of a measurement result.

An electrolyte analysis device 100 that measures a concentration of a specific ion in a sample using a plurality of ion selective electrodes of an ion selective electrode group 102, and a reference electrode 103 includes a water supply tank 107 configured to store system water used for at least one of solution sending, probe cleaning, and temperature adjustment in the electrolyte analysis device 100, a specimen dispensing device 101 configured to dispense a sample to be measured, a dilution tank 106 configured to dilute the sample dispensed by the specimen dispensing device 101 with the system water, a water quality measurement unit 200 configured to measure the ion concentration of the system water in the water supply tank 107, and a control device 111 configured to control the electrolyte analysis device 100, in which the control device 111 performs water quality determination processing of determining whether a water quality of the system water is normal or abnormal based on a measurement result of the water quality measurement unit 200.

A method for nucleic acid sequencing includes receiving a plurality of observed or measured signals indicative of a parameter observed or measured for a plurality of defined spaces; determining, for at least some of the defined spaces, whether the defined space comprises one or more sample nucleic acids; processing, for at least some of the defined spaces, the observed or measured signal to improve a quality of the observed or measured signal; generating, for at least some of the defined spaces, a set of candidate sequences of bases for the defined space using one or more metrics adapted to associate a score or penalty to the candidate sequences of bases; and selecting the candidate sequence leading to a highest score or a lowest penalty as corresponding to the correct sequence for the one or more sample nucleic acids in the defined space.

A method for nucleic acid sequencing includes receiving a plurality of observed or measured signals indicative of a parameter observed or measured for a plurality of defined spaces; determining, for at least some of the defined spaces, whether the defined space comprises one or more sample nucleic acids; processing, for at least some of the defined spaces, the observed or measured signal to improve a quality of the observed or measured signal; generating, for at least some of the defined spaces, a set of candidate sequences of bases for the defined space using one or more metrics adapted to associate a score or penalty to the candidate sequences of bases; and selecting the candidate sequence leading to a highest score or a lowest penalty as corresponding to the correct sequence for the one or more sample nucleic acids in the defined space.