G01N2021/8416

IR SPECTROSCOPE CELL CULTURE ANALYSIS
20230068250 · 2023-03-02 ·

A method of detection of a status of cells within a cell culture is described. The method is based on comparing an IR spectrum of a test sample obtained from the cell culture with an IR spectrum of a control sample or samples or with an IR spectrum of a sample or samples obtained at an earlier time point in the cell culture and correlating differences between the spectra with the status of the cells. The status may be classified into healthy or unhealthy. The test sample may or may not contain cells. The test sample may contain cell fragments, cell components or cell media, or may be cell supernatant. The comparison may be performed using a predictive model based on pattern recognition algorithms, such as support vector machines SVM, linear discriminant analysis LDA, principal component discriminant function analysis PC-DFA, neural networks, or random forests). The analysis results may be used to monitor and/or control the cell culturing process.

MAKING AND INSPECTING A WEB OF VITREOUS LITHIUM SULFIDE SEPARATOR SHEET AND LITHIUM ELECTRODE ASSEMBLIES AND BATTERY CELLS

A lithium ion-conductive solid electrolyte including a freestanding inorganic vitreous sheet of sulfide-based lithium ion conducting glass is capable of high performance in a lithium metal battery by providing a high degree of lithium ion conductivity while being highly resistant to the initiation and/or propagation of lithium dendrites. Such an electrolyte is also itself manufacturable, and readily adaptable for battery cell and cell component manufacture, in a cost-effective, scalable manner. An automated machine based system, apparatus and methods assessing and inspecting the quality of such vitreous solid electrolyte sheets, electrode sub-assemblies and lithium electrode assemblies can be based on spectrophotometry and can be performed inline with fabricating the sheet or web (e.g., inline with drawing of the vitreous Li ion conducting glass) and/or with the manufacturing of associated electrode sub-assemblies and lithium electrode assemblies and battery cells.

System and method of inline deposit detection in process fluid

The disclosed systems and method utilize the autofluorescence, optic imaging, and heat transfer resistance technologies to monitor the same simulated surface area for deposits. The systems and methods may provide continuous monitoring, detection, characterization and quantification of deposits. Utilizing this information, an associated control system may initiate alarms, initiate a chemical treatment operation, and adjust corresponding chemical treatment and preventive protocols to minimize and/or eradicate the issue.

SYSTEMS AND METHODS FOR THE IN-LINE MEASUREMENT OF ALKALI METAL-CONTAINING STRUCTURES AND ALKALI ION-CONTAINING STRUCTURES
20230160821 · 2023-05-25 ·

Embodiments of the present disclosure generally relate to systems and methods for in-line measurement of alkali metal-containing structures or alkali ion-containing structures of, e.g., electrodes. In an embodiment, a system for processing an electrode is provided. The system includes a first processing chamber for forming an electrode comprising an alkali metal-containing structure. The system further includes a metrology station coupled to and in-line with the first processing chamber, the metrology station comprising: a source of radiation for delivering radiation to the alkali metal-containing structure, and an optical detector for receiving an emission of radiation emitted from the alkali metal-containing structure, and a processor configured to determine a characteristic of the alkali metal-containing structure of the electrode based on the emission of radiation.

Method for Simultaneously Determining Parameters of at Least One Resin Layer Applied to at Least One Carrier Material
20230145539 · 2023-05-11 ·

Provided is a method for the simultaneous determination of parameters, in particular of at least two, three or four parameters, of at least one resin layer applied to at least one carrier material by recording and evaluating at least one NIR spectrum in a wavelength range between 500 nm and 2500 nm, preferably between 700 nm and 2000 nm, more preferably between 900 nm and 1700 nm, and particularly advantageously between 1450 nm and 1550 nm, using at least one NIR measuring head, in particular at least one NIR multimeter head.

AUTOMATIC CONTROL SYSTEM AND METHOD FOR WATER TREATMENT OF THERMAL STERILIZATION KETTLE

The present disclosure relates to an automatic control system and method for water treatment of a thermal sterilization kettle. The system comprises a sampling module, a monitoring module and a control module, wherein the sampling module is used for respectively sampling hot water and cold water, and the monitoring module is arranged to respectively monitor online fluorescence signals in the sampled hot water and the sampled cold water; the control module is used for respectively controlling whether to add a compound medicament into a hot water area or not according to the online fluorescence signal of the sampled hot water and controlling whether to add the compound medicament into a cold water area or not according to the online fluorescence signal of the sampled cold water; and meanwhile, the monitoring module is further used for monitoring the residual chlorine signal of the sampled cold water.

System and method for alkylation process analysis

A method and apparatus is provided for concentration determination of at least one component in an acid catalyst for hydrocarbon conversion containing an unknown concentration of an acid, an acid-soluble-oil (ASO), and water. An instrument configured for measuring a property of the acid catalyst, has responsivities to concentrations of one of the acid, ASO, and water, substantially independent of the concentrations of the others of the acid catalyst, ASO, and water. A temperature detector is configured to generate temperature data for the acid catalyst. A processor is configured to capture data generated by the temperature detector and the instrument, and to use the data in combination with a model to determine a temperature compensated concentration of the one of the acid, the ASO, and the water. Optionally, one or more other instruments configured for measuring other properties of the liquid mixture may also be used.

Integrated system for real-time anti-fouling and biofouling monitoring

The invention provides an anti-biofouling system (200) comprising an UV-emitting element (210), wherein the UV-emitting element (210) comprises a UV radiation exit window (230), wherein the UV-emitting element (210) at least partly encloses a light source (220) configured to provide UV radiation (221), wherein the UV radiation exit window (230) is configured to transmit at least part of the UV radiation (221) of the light source (220), wherein the UV radiation exit window (230) comprises an upstream window side (231) and a downstream window side (232), wherein the UV-emitting element (210) also at least partly encloses an optical sensor (310) configured to sense radiation (421) emanating from the downstream window side (232) and configured to provide a corresponding optical sensor signal, wherein the anti-biofouling system (200) is further configured to provide said UV radiation (221) in dependence of said optical sensor signal.

Apparatus with closed loop feedback for forming a nanostructured thin film with porosity gradient on an array of sloped outdoor panel surfaces using meniscus drag
11682738 · 2023-06-20 ·

A thin-film coating applicator assembly is disclosed for coating substrates in outdoor applications. The innovative thin-film coating applicator assembly is adapted to apply performance enhancement coatings on installed photovoltaic panels and glass windows in outdoor environments. The coating applicator is adapted to move along a solar panel or glass pane while applicator mechanisms deposit a uniform layer of liquid coating solution to the substrate's surface. The applicator assembly comprises a conveyance means disposed on a frame. Further disclosed are innovative applicator heads that comprise a deformable sponge-like core surrounded by a microporous layer. The structure, when in contact with a substrate surface, deposits a uniform layer of coating solution over a large surface.

COMPUTER-IMPLEMENTED METHOD AND SYSTEM FOR SPECTROSCOPIC ANALYSIS OF BIOLOGICAL MATERIAL

A computer-implemented method for spectroscopic analysis of biological material is provided that includes analyzing samples of biological material from a plurality of sources, and delivering samples of biological material to at least one flow cell for spectroscopy, and determining whether the spectroscopic analysis for each sample of the plurality of samples is or is predicted to be ambiguous in that it is affected by at least two non-discriminable factors. If such a determination is made, a disambiguating step can be performed.