A measurement device measures changes over time of a concentration of a measurement substance that occurs due to a reaction occurring as a result of a solution containing the analyte being dripped onto an electrode, by measuring an electric current that occurs due to electrolysis of the measurement substance. The measurement device applies a first voltage over a first application time period. The measurement device measures a first electric current flowing due to an application of the first voltage. The measurement device applies a second voltage over a second application time period. The measurement device a second electric current flowing due to an application of the second voltage. The measurement device uses the first electric current to normalize the second electric current and measures a concentration of the measurement substance that has changed based on the reaction or a concentration of the analyte that has changed based on the reaction.

An electrolyte analysis apparatus measures the concentration of a specific ion in a specimen based on the result of measuring a reagent having a predetermined ion concentration by an ion selective electrode and the result of measuring the specimen by the ion selective electrode. The electrolyte analysis apparatus includes a reagent unit for diluting and restoring a concentrated internal standard solution having a concentration higher than a predetermined ion concentration with pure water to generate a reagent having the predetermined ion concentration, and a mechanism, in which the reagent generation unit generates the reagent such that the absolute value of the temperature difference between the reagent obtained by the dilution and restoration, and the pure water is smaller than the absolute value of the temperature difference between the reagent obtained by the dilution and restoration, and the reagent stock solution.

Apparatus (200) for detecting corrosion of a coating (250) of an object (216), the apparatus comprising: an electrically conductive body (202) defining a cavity (204) for containing an electrolyte (206), the body (202) arranged to be, in use, in electrically conductive contact with the object (216) and arranged to isolate, in use, the electrolyte (206) from the object; and a first electrode (208) within the cavity (204), the first electrode (208) for electrical connection to a potentiostat (402) or to a galvanostat and arranged to be, in use, in electrical contact with the electrolyte (206) in the cavity (204); wherein the body (202) comprises a first part (222) and a second part (224), the second part (224) being slidably movable relative to the first part (222) between a retracted position and an extended position.

An object of the present invention is to provide a device for measuring electrolyte concentration capable of easily measuring a temperature difference between a sensitive membrane and liquid in the vicinity of the sensitive membrane that affects an electrolyte concentration analysis value. The device for measuring electrolyte concentration according to the present invention measures potential of an ion selective electrode at at least two or more different times while liquid is present in a flow path for introducing the liquid into the ion selective electrode, and calculates a temperature difference between the liquid and the ion selective electrode using the measured potential of the ion selective electrode at two or more different times (see FIG. 4).

A system for separating and analyzing a discrete sample of multiphase fluid includes a separation vessel having a first inner chamber containing a discrete sample of multiphase fluid, and an analytical cell in fluid communication with the separation vessel. The analytical cell has a second inner chamber containing a diluted aqueous liquid phase sample for analysis. The system further includes probes disposed in the second inner chamber, each probe having a sensing area at a distal end, and being oriented in the second inner chamber such that the sensing area is immersed in the diluted aqueous liquid phase sample contained in the second inner chamber. The plurality of probes include a first probe whose sensing area surface is coated with a first ion-exchange membrane; and a second probe whose sensing area surface is coated with a second ion-exchange membrane, the second ion-exchange membrane being different from the first ion-exchange membrane.

The invention relates to a new method of characterising a target ribonucleic acid (RNA) involving forming a complementary polynucleotide. The method uses a transmembrane pore.

Provided is an electrolyte analysis device capable of suppressing a burden with respect to measurement while suppressing a decrease in accuracy of a measurement result.

An electrolyte analysis device 100 that measures a concentration of a specific ion in a sample using a plurality of ion selective electrodes of an ion selective electrode group 102, and a reference electrode 103 includes a water supply tank 107 configured to store system water used for at least one of solution sending, probe cleaning, and temperature adjustment in the electrolyte analysis device 100, a specimen dispensing device 101 configured to dispense a sample to be measured, a dilution tank 106 configured to dilute the sample dispensed by the specimen dispensing device 101 with the system water, a water quality measurement unit 200 configured to measure the ion concentration of the system water in the water supply tank 107, and a control device 111 configured to control the electrolyte analysis device 100, in which the control device 111 performs water quality determination processing of determining whether a water quality of the system water is normal or abnormal based on a measurement result of the water quality measurement unit 200.

Apparatus and methods are provided for measuring phosphate in water. The methods can involve electrically pre-treating a potentiometric sensor and using the electrically pre-treated potentiometric sensor in a water sample to obtain a phosphate measurement. The potentiometric sensor includes a working electrode and a counter electrode. The working electrode includes a metal/metal oxide electrode having a detection surface. The electrical pre-treatment generates a metal phosphate on the detection surface of the metal/metal oxide electrode. The phosphate measurement results in a fresh layer of mixed oxide on the detection surface of the metal/metal oxide electrode. The electrically pre-treatment can be performed in situ in the water sample, allowing for field monitoring of water bodies. In some embodiments, the method can also involve cleaning the sensor prior to electrically pre-treating the sensor or after obtaining the phosphate measurement.

Provided is a method for measuring a component of a biological sample with a biosensor provided with: a capillary for introducing the biological sample; an electrode part including a first electrode system that includes a first working electrode and a first counter electrode in the capillary; and a reagent part disposed so as to be in contact with the electrode part, the reagent part containing an enzyme and a mediator, and the method including a step of starting voltage application for a duration longer than 0 second and up to 0.7 second to the first electrode system within 0 second to 0.5 second after detection of the introduction of the biological sample to obtain a hematocrit value based on a current value obtained thereby.

Methods for manufacturing an electrochemical sensor include forming at least one electrode by printing at least one conductive ink on a surface of at least one substrate. The conductive ink may comprise, e.g., a platinum-group metal, another transition-group metal with a high-temperature melting point, a conductive ceramic material, glass-like carbon, or a combination thereof. The electrochemical sensor may be free of another material over the at least one electrode. An electrochemical sensor, formed according to such methods, may be configured for use in harsh environments (e.g., a molten salt environment). Electrodes of the electrochemical sensor comprise conductive material formed from a printed, conductive ink. In some embodiments, at least a portion of the electrochemical sensor is free of silver, gold, copper, silicon, and polymer materials, such portion being that which is to be exposed to the harsh environment during use of the electrochemical sensor.