Disclosed herein are automated processes and systems for determining an underlying cause of anemia. Also disclosed herein are processes and systems for determining an underlying cause of microcytic anemia, normocytic anemia, and macrocytic anemia. Additionally disclosed herein are methods of treating the underlying cause of anemia in an individual in need thereof.

Disclosed herein are automated processes and systems for determining an underlying cause of anemia. Also disclosed herein are processes and systems for determining an underlying cause of microcytic anemia, normocytic anemia, and macrocytic anemia. Additionally disclosed herein are methods of treating the underlying cause of anemia in an individual in need thereof.

A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.

A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.

Artificial blood for a bloodstain pattern analysis includes water, an amino acid solution, bovine serum albumin, hemoglobin from bovine blood, potassium ferricyanide, sodium hyaluronate, sodium chloride, and tar color.

Artificial blood for a bloodstain pattern analysis includes water, an amino acid solution, bovine serum albumin, hemoglobin from bovine blood, potassium ferricyanide, sodium hyaluronate, sodium chloride, and tar color.

The present invention relates to an in-vitro method for detecting anti-erythrocyte antibodies in a sample, comprising at least the following steps: a) bringing the sample into contact with one or more test erythrocytes or a suspension of one or more test erythrocytes having a known phenotype, under conditions likely to induce hemagglutination, so as to obtain a reaction mixture; b) bringing the reaction mixture into contact with a solid substrate containing a plurality of defined adsorption areas which have previously fixed antibodies or antibody fragments capable of binding antigenic determinants present on the one or more test erythrocytes; c) ascertaining the presence or absence of a hemagglutination reaction in at least one of the adsorption areas so as to detect the presence or absence of anti-erythrocyte antibodies in the sample; the steps a) and b) being carried out separately or simultaneously.

The present invention relates to an in-vitro method for detecting anti-erythrocyte antibodies in a sample, comprising at least the following steps: a) bringing the sample into contact with one or more test erythrocytes or a suspension of one or more test erythrocytes having a known phenotype, under conditions likely to induce hemagglutination, so as to obtain a reaction mixture; b) bringing the reaction mixture into contact with a solid substrate containing a plurality of defined adsorption areas which have previously fixed antibodies or antibody fragments capable of binding antigenic determinants present on the one or more test erythrocytes; c) ascertaining the presence or absence of a hemagglutination reaction in at least one of the adsorption areas so as to detect the presence or absence of anti-erythrocyte antibodies in the sample; the steps a) and b) being carried out separately or simultaneously.

Compositions and methods are provided for loading cargoes onto red blood cells. Provided herein are novel antibodies, fragments, fusion proteins and other conjugates which specifically bind red blood cells via RHCE or Band 3.

The present disclosure relates to compositions and methods for determining the quality of stored blood and detecting Autologous Blood Transfusions (ABT) and blood doping.