The invention relates to an optical device for detecting and quantifying volatile compounds, comprising: a sensitive reflective element (21), the reflection rate of which varies as a function of the ethanol content contained in an atmosphere to be tested, the sensitive reflective element (21) comprising: a substrate (27), a sensitive layer (29) comprising microporous hydrophobic sol-gel silica, a light source (23) arranged to illuminate the sensitive layer (29) under an incident angle, a light detector (25) for measuring the intensity reflected by the reflective element (21) under an angle of detection, and a processing and calculation unit (31) configured to deduce from the intensity reflected by the reflective element (11) a parameter corresponding to a blood alcohol content.

The invention relates to an optical device for detecting and quantifying volatile compounds, comprising: a sensitive reflective element (21), the reflection rate of which varies as a function of the ethanol content contained in an atmosphere to be tested, the sensitive reflective element (21) comprising: a substrate (27), a sensitive layer (29) comprising microporous hydrophobic sol-gel silica, a light source (23) arranged to illuminate the sensitive layer (29) under an incident angle, a light detector (25) for measuring the intensity reflected by the reflective element (21) under an angle of detection, and a processing and calculation unit (31) configured to deduce from the intensity reflected by the reflective element (11) a parameter corresponding to a blood alcohol content.

A device and a process detects alcohol in a gas sample, especially in an exhaled breath sample. A measuring chamber (2) receives the gas sample to be tested. Two IR radiation sources (7, 11) are configured to transmit an IR beam each into the measuring chamber (2). Two IR detectors (9, 13) generate a measured value each depending on an incident IR beam. An analysis unit (10) automatically makes a decision on whether or not the gas sample contains alcohol, doing so depending on the two measured values from the two IR detectors (9, 13).

Ethyl glucuronide (EtG) lateral flow immunoassay test strips, devices, and methods, useful for testing for alcohol ingestion for alcohol abuse or related diseases and treatment monitoring.

Ethyl glucuronide (EtG) lateral flow immunoassay test strips, devices, and methods, useful for testing for alcohol ingestion for alcohol abuse or related diseases and treatment monitoring.

Systems and methods detect a target analyte in a breath sample. The system includes a sensor device and an analyzer. The sensor device includes a breath capture mechanism for capturing the target analyte from the breath sample. The captured analyte is transferred to a testing solution. The sensor device includes a receptor for selectively binding the target analyte. The receptor and the bound analyte together form a receptor-analyte complex. The sensor device also includes a sensor. The sensor includes at least one electrode. A surface of the at least one electrode binds the receptor-analyte complex when the sensor is exposed to the testing solution containing the target analyte. The analyzer analyzes the sensor to determine a target analyte level. The analyzer includes an electronics subsystem for determining a change in an electrical property of the sensor caused by the presence of the receptor-analyte complex. The analyzer generates the target analyte level based on the change in the electrical property.

Systems and methods detect a target analyte in a breath sample. The system includes a sensor device and an analyzer. The sensor device includes a breath capture mechanism for capturing the target analyte from the breath sample. The captured analyte is transferred to a testing solution. The sensor device includes a receptor for selectively binding the target analyte. The receptor and the bound analyte together form a receptor-analyte complex. The sensor device also includes a sensor. The sensor includes at least one electrode. A surface of the at least one electrode binds the receptor-analyte complex when the sensor is exposed to the testing solution containing the target analyte. The analyzer analyzes the sensor to determine a target analyte level. The analyzer includes an electronics subsystem for determining a change in an electrical property of the sensor caused by the presence of the receptor-analyte complex. The analyzer generates the target analyte level based on the change in the electrical property.

Provided herein are flexible, microfluidic epidermal systems and methods useful in the analysis of biofluids for biomarkers corresponding to a variety of conditions and methods of use. The provided systems configured to create conformal contact with the skin to allow for medical testing or screening, either in situ or later external laboratory testing. The described devices and methods may be used for cystic fibrosis screening, glucose monitoring, drug and/or alcohol testing, creatinine monitoring, urea monitoring, pH measurement and dialysis treatment efficacy testing.

Provided herein are flexible, microfluidic epidermal systems and methods useful in the analysis of biofluids for biomarkers corresponding to a variety of conditions and methods of use. The provided systems configured to create conformal contact with the skin to allow for medical testing or screening, either in situ or later external laboratory testing. The described devices and methods may be used for cystic fibrosis screening, glucose monitoring, drug and/or alcohol testing, creatinine monitoring, urea monitoring, pH measurement and dialysis treatment efficacy testing.

An apparatus and associated method are provided for sensing an analyte, such as acetone, in breath. The apparatus includes a sorbent material that extracts the analyte from a dehumidified breath sample, and a nanoparticle-based sensor. The apparatus produces first and second gas streams that flow over the nanoparticle-based sensor. The first gas stream is used to generate a baseline signal, and the second gas stream is used to carry the extracted analyte from the sorbent material to the nanoparticle-based sensor. Various additional designs of analyte sensing devices are also disclosed.