An optical measuring device for the spectral measurement of a sample is disclosed. The optical measure device includes an integrating cavity that has a diffusely reflective interior in order to render the light in the integrating cavity diffuse, a light source that is configured to emit light of a predetermined wavelength range into the integrating cavity, and a sensor that is configured to receive light from the integrating cavity, wherein the integrating cavity comprises an optical opening, and wherein the optical measuring device is provided and configured to measure a sample located outside of the integrating cavity directly in front of the optical opening.

A system of measuring hemoglobin and bilirubin parameters in a whole blood sample using optical absorbance. The system includes an optical-sample module, a spectrometer module, an optical fiber module optically connecting the optical-sample module to the spectrometer module, and a processor module. The optical-sample module has a light-emitting module having a LED light source, a cuvette and a calibrating-light module. The processor module receives and processes an electrical signal from the spectrometer module and transforms the electrical signal into an output signal useable for displaying and reporting hemoglobin parameter values and/or total bilirubin parameter values for the whole blood sample.

A method of measuring whole-blood hemoglobin parameters includes providing a LED light source, guiding light having the spectral range from the LED light source along an optical path, providing a cuvette module with a sample receiving chamber, providing a pair of first and second optical diffusers disposed in the optical path where the cuvette module is disposed between the pair of first and second optical diffusers, guiding light from the cuvette module into an optical spectrometer, and processing an electrical signal from the spectrometer into an output signal useable for displaying and reporting hemoglobin parameter values and/or total bilirubin parameter values of the sample of whole blood.

A non-dispersive multi-channel radiation sensor assembly includes a beamsplitter assembly, a first band-pass filter, which has a predefined first bandwidth and has a transmission maximum at a predefined first useful-signal wavelength, a first measurement-radiation useful-signal sensor, which is arranged downstream of the first band-pass filter in the beam path, a second band-pass filter, which has a transmission maximum at a predefined first reference-signal wavelength, a first measurement-radiation reference-signal sensor, which is arranged downstream of the second band-pass filter in the beam path. The beamsplitter assembly has a first irradiation region and a second irradiation region, in which irradiation regions the beamsplitter assembly is irradiated with measurement radiation. The irradiation regions are optically designed in such a way that the beamsplitter assembly deflects, in the first irradiation region, a first part of the measurement radiation onto the first band-pass filter and a second part of the measurement radiation onto the second band-pass filter.

The molecule detecting apparatus of an embodiment includes a light source 31, a fluorescent layer 42 emitting different fluorescence depending on the kind of a target molecule 60 captured when being irradiated with light from the light source 31, a photodetector 32 configured to detect fluorescence, and the photodetector 32 is an array of avalanche photodiodes operating in Geiger mode.

A component inspection process includes positioning a component (e.g., a semiconductor component or other object) such that component sidewalls are disposed along an optical path corresponding to sidewall beam splitters configured for receiving sidewall illumination provided by a set of sidewall illuminators, and transmitting this sidewall illumination therethrough, toward and to component sidewalls. Sidewall illumination incident upon component sidewalls is reflected from the component sidewalls back toward the sidewall beam splitters, which reflect or redirect this reflected sidewall illumination along an optical path corresponding to an image capture device for sidewall image capture to enable component sidewall inspection. Sidewall illuminators and sidewall beam splitters can form portions of a five sided inspection apparatus that includes a brightfield illuminator, a darkfield illuminator, and an image capture beam splitter such that the five sided inspection apparatus is configurable for inspecting component bottom surfaces and/or component sidewalls in a selective/selectable manner.

Apparatus and methods for acquiring a Raman spectral map of a sample including a material species. The apparatus includes: a pulsed illumination source providing pulsed illumination radiation for exciting the sample and producing scattered radiation; a microscope objective focusing the pulsed illumination radiation onto a region of the sample corresponding to a data point of the map, and collecting emitted radiation from the region; a translation stage translating the sample relative to the microscope objective in at least two directions; a spectral filter spectrally filtering the emitted radiation collected by the objective to obtain a filtered portion of radiation corresponding to a characteristic Raman spectral feature of the material species; a detector receiving the filtered portion and providing output electrical pulses indicative thereof; and readout electronics applying a time gate to the output electrical pulses to distinguish detection events corresponding to the Raman scattered radiation from events associated with photoluminescence.

A multi-mode illumination system, including: a first illumination module; a second illumination module; and a third illumination module, as disclosed herein.

Provided herein is an apparatus for assessing a color characteristic of a gemstone. The apparatus comprises an optically opaque platform for supporting a sample gemstone to be assessed, a daylight-approximating light source to provide uniform illumination to the gemstone, an image capturing component, and a telecentric lens positioned to provide an image of the illuminated gemstone to the image capturing component. Also provided are methods of color analysis based on images collected using such an apparatus.

An apparatus for characterizing a specimen and/or specimen container. The characterization apparatus includes an imaging location configured to receive a specimen container containing a specimen, a light source configured to provide lighting of the imaging location, and a hyperspectral image capture device. The hyperspectral image capture device is configured to generate and capture a spectrally-resolved image of a small portion of the specimen container and specimen at a spectral image capture device. The spectrally-resolved image data received at the spectral image capture device is processed by a computer to determine at least one of: segmentation of at least one of the specimen and/or specimen container, and determination of a presence or absence of an interferent, such as hemolysis, icterus, or lipemia. Methods of imaging a specimen and/or specimen container, and specimen testing apparatus including a characterization apparatus are described, as are other aspects.