A handle for maneuvering a catheter, comprises: a handle body having an outer surface and an inner surface, the inner surface defining a tubular passage extending along a longitudinal axis from a proximal end to a distal end of the handle body. The handle includes a coupling mechanism at the proximal end and a strain relief sleeve at the distal end of the handle body. The strain relief sleeve is adapted to irremovably secure a flexible catheter sheath to the handle; and the coupling mechanism is adapted to detachably connect the handle to a patient interface unit (PIU). The handle body is ergonomically sized and shaped for grasping by a single hand of a user, and is configured to linearly engage to and disengage from the PIU via the coupling mechanism. When the handle is attached to the PIU, an imaging core moves linearly inside the tubular passage without bending.

Intravascular devices, systems, and methods are disclosed. In some embodiments, a medical imaging system for imaging vasculature of a patient is provided. The imaging system includes a console that has one or more processors with a medical imaging system interface running thereon, an acquisition card in communication with the one or more processors and in communication with a patient interface module (PIM), and an intravascular imaging component in communication with the PIM and disposed on a distal end of a flexible elongate member. The medical imaging system interface provides a plurality of settings groups for selection by a user, each of the settings groups having pre-acquisition parameters and post-acquisition parameters that are optimal for imaging a desired viewing target within the vasculature. Associated methods and computer-readable media are provided.

Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties.

Examples of the disclosure relate to an apparatus (101), a wearable electronic device and an optical arrangement for optical coherence tomography. The apparatus comprises an optical coherence tomography system (103) and an optical arrangement (105). The optical arrangement comprises at least one means for beam shaping (109) configured to shape a beam of light from the optical coherence tomography system. The optical arrangement also comprises at least one minor (111) positioned so that light from the means for beam shaping is incident on the at least one minor. The at least one mirror is configured to move in at least one direction relative to the optical coherence tomography system.

The invention relates to an assembly comprising a interferometer for carrying out an optical coherence tomography, wherein the interferometer is divided into two spatially spaced-apart interferometer parts (1, 2), wherein the two interferometer parts (1, 2) can be moved related to one another and are optically connected to one another via flexible light guides (3, 4, 5), which bridge the spatial distance, wherein according to the invention, an assembly having an interferometer is provided, which is as unsusceptible as possible to the effects brought about by bending a tube cable packet and allows for an optimum signal-to-noise ratio or an optimum image quality of an OCT image, characterised in that at least one first flexible light guide (3) is designed as a polarisation-maintaining light guide consisting of two connected polarisation-maintaining light-guiding fibres (3a, 3b).

A method for operating an optical tomographic imaging apparatus according to the present invention includes: an initial setting step of setting initial positions of a reference mirror and a distal end of an optical part; an imaging step of imaging a biological tubular element after the initial setting step; a reference mirror adjustment step of, after the imaging step, moving the reference mirror to enlarge the image portion of the reflected light from the biological tubular element and the image portion of the reflected light from the tube while reducing an image portion of an artifact caused by reflected light from the optical part, and adjusting the image portion of the artifact to an inside of the image portion of the reflected light from the tube; a magnification adjustment step of, after the reference mirror adjustment step, resetting the image portion of the reflected light from the biological tubular element and the image portion of the reflected light from the tube to a state before the enlargement; and a display step of, after the magnification adjustment step, causing an image display unit to display the image portion of the reflected light from the biological tubular element and the image portion of the reflected light from the tube reset to the state before enlargement.

Disclosed is an optical coherence tomography (OCT) system according to an exemplary embodiment of the present disclosure. The OCT system may include: a light source unit generating light; an optical interferometer including an optical coupler splitting the light generated by the light source unit into first distribution light and second distribution light, a reference arm reflecting the first distribution light, a sample arm reflecting the second distribution light, and an optical detector detecting the light reflected by the reference arm and the sample arm; an OCT catheter including an optical fiber having a shape in which the optical fiber is insertable into at least a part of a human body and is rotatable and discharging the light to a tissue and collecting OCT data for the tissue; an OCT engine including a processor and a storage unit and processing the OCT data collected by the OCT catheter; and an OCT controller connected to a proximal end of the OCT catheter and controlling rotation of the OCT catheter.

An optical source sweeps a source light over an optical wavelength range. An interferometer splits the source light into sample light and reference light, delivers the sample light into an anatomical structure, such that the sample light is scattered by the anatomical structure, resulting in physiological-encoded signal light that exits the anatomical structure, and combines the signal light and the reference light into an interference light pattern having an array of spatial components and a plurality of oscillation frequency components. An optical detector array detects intensity values of the array of spatial components. A processor derives an array of intensity values of each oscillation frequency component from the detected spatial component intensity value array, reduces each derived oscillation frequency component intensity value array to a single frequency component intensity value, and determines a depth of a physiological event in the anatomical structure based on the reduced frequency component intensity values.

A neural network is trained for estimating patient hemodynamic data using a plurality of extravascular imaging data sets and a plurality of intravascular imaging data sets that are each co-registered to a corresponding extravascular imaging data set. A plurality of hemodynamic data sets are provided, each hemodynamic data set co-registered with the corresponding extravascular imaging data set. The neural network learns what hemodynamic data to expect for a given intravascular imaging data set. An intravascular imaging event is subsequently performed in which an intravascular imaging element is translated within a blood vessel of the patient to produce one or more intravascular images. The neural network uses its training to predict hemodynamic values corresponding to the one or more intravascular images from the intravascular imaging event, and the one or more intravascular images are outputted in combination with the predicted hemodynamic values.

A medical apparatus, method, or storage medium to perform monitoring a sensor of the medical apparatus to obtain a sensor reading, performing impact detection based on the sensor reading, generating an impact profile based on the impact detection, characterizing the impact detection, and responding to the impact detection.