A nasal cannula having a face piece including first and second nares which each communicate with a respective nostril of a patient. A septum divides the face piece into first and second flow paths such that the first flow path communicates with the first nare and the second flow path communicates with the second nare. A leading end of the first nare is configured to form a fluid barrier within a first nostril and facilitate only supplying an insufflation gas, via the first flow path, to the patient and prevent exhausting any exhaust gas, of the patient, through the first nostril. A leading end of the second nare is configured to facilitate collecting some of the exhaust gas, from the patient, via the second flow path as well as exhausting a remainder of the exhaust gas out through a second nostril of the patient.

There are provided Nano-Opto-Mechanical sensors for measuring concentration of a component in a gas flow, methods for their use and system comprising the same.

Among other things, we describe a system that includes a first medical device for treating a patient at an emergency care scene, the first medical device including a processor and a memory configured to detect a request for a connection between the first medical device and a second medical device for treating the patient at the emergency care scene, the request for connection including an identifier of the second medical device, responsive to receiving the request for connection, enabling a wireless communication channel to be established between the first medical device and the second medical device based on the identifier of the second medical device and an identifier of the first medical device; and enabling transmission and/or exchange of patient data between the first medical device and the second medical device via the wireless communication channel. Such communications with more than two devices may also be possible.

A system and method are provided that employ a monitoring device to monitor at least one patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. In turn, an output (e.g. a visual and/or auditory output) may be provided to a user indicative of at least one measure of patient response to the change in temperature. Alternatively or additionally, a processor may be provided to process the monitoring signal and provide an output employable by medical personnel to control a patient shivering response to the patient temperature change. Such information may comprise information regarding one or more anti-shivering medicament(s), e.g. corresponding dosage and/or frequency information for use by medical personnel in the administration of the anti-shivering medicament. In one approach, a motion sensor may be selectively attached to a patient's chin to provide a wireless monitoring signal to a transceiver. In turn, the transceiver may provide the monitoring signal to the processor on an ongoing basis to output information useful in the administration of an anti-shivering medicament, including updated information that takes into account a patient's response to a prior administration of one or more medicaments in conjunction with the subsequent administration of an anti-shivering medicament.

Values of components of total carbon dioxide excreted by a subject can be provided. One or more signals may be received conveying information related to a rate of total carbon dioxide excreted by the subject. Based at least in part on the received one or more signals, a first capnometric component and/or a second capnometric component may be determined. The first capnometric component may indicate a rate of metabolic carbon dioxide production. The second capnometric component may indicate a rate of carbon dioxide transfer to or from body compartments of the subject that store carbon dioxide. The first capnometric component and/or the second capnometric component may be presented to a user.

Systems and methods for providing respiratory pacing using a closed-loop adaptive controller that can self-adjust in real-time to meet metabolic needs of a subject are provided. The controller can use an adaptive pattern generator/pattern shaper architecture that can autonomously generate a desired ventilatory pattern in response to dynamic changes in arterial carbon dioxide levels and, based on a learning algorithm or machine learning, can modulate stimulation intensity and cycle duration to evoke the desired ventilatory pattern.

Systems and methods for estimating a ventilatory threshold for a patient and estimating likelihood of pulmonary arterial hypertension are provided. An example method includes determining ratios of minute ventilation to rate of oxygen uptake based on breath-by-breath data for a patient. The example method also includes determining a ventilatory threshold based upon the determined ratios and determining a score based upon an end-tidal partial pressure of carbon dioxide (PetCO2) value at the determined ventilatory threshold and a minute ventilation/carbon dioxide production relationship (VE/VCO2) value at the determined ventilatory threshold. The method also includes using the score to estimate a likelihood that the patient has pulmonary arterial hypertension and causing the estimated likelihood to be displayed on a user interface.

The present invention provides an improved breath analyzer and breath test method to determine the presence of disease in humans, including but not limited to, the bacterium H. pylori in a subjects digestive tract. In certain embodiments, the present invention provides a universal breath testing platform and methods of testing for diseases of the gastrointestinal tract, the liver, the kidneys, and the lungs, along with testing for cancer, infections, and metabolic diseases.

A method of detecting hypoxia. Detecting hypoxia includes detecting, in exhaled breath, at least one indicator for hypoxia. The at least one indicator is selected from the group consisting of pentanal, 2-pentanone, 2-hexanone, 2-heptanone, 2-cyclopenten-1-one, and 4-butyrolactone.

A capnoscope assembly for measuring carbon dioxide (CO2) concentration, and an associated method. The assembly includes a detection unit, an indicator holder, a processing unit, and a calibration member. The processing unit adjusts light parameters such that a camera detects a predetermined calibration colour. A colorimetric indicator is arranged to be used in the indicator holder. The colour of the colorimetric indicator surface is measured when illuminated by emitted light being generated by using determined calibrated control signal values, when no CO2 is present. The measured colour is stored as a zero CO2 colour value. A CO2 concentration relationship is determined based upon the measured zero CO2 colour value. The processing unit applies the CO2 concentration relationship during CO2 concentration measurements provided that the determined calibrated control signal values are applied when emitting light.