A wearable sweat sensing device configured to be placed on a wearer's skin includes a sensor component, including at least one analyte-specific sensor for measuring a target analyte in sweat, and at least one electromagnetic shield to protect at least a portion of the sensor component from electromagnetic interference. The at least one electromagnetic shield may include a first electromagnetic shield for protecting the sensor component from electromagnetic interference originating outside the wearer's body and a second electromagnetic shield for protecting the sensor component from electromagnetic interference originating from the wearer's body or propagating through the wearer's body.

A charging system can include a housing. The housing can include a controller. The housing also can include a power source configured to power the controller. The charging system also can include a wireless charger configured to transfer energy to the power source. The wireless charger can include a first indicator. The first indicator can be configured to provide a first non-flashing visual output at a first brightness level and indicative of a first charging status of the power source. The first indicator also can be configured to provide a second non-flashing visual output at a second brightness level indicative of a second charging status of the power source. Other embodiments are disclosed.

Described here are embodiments of processes and systems for the continuous manufacturing of implantable continuous analyte sensors. In some embodiments, a method is provided for sequentially advancing an elongated conductive body through a plurality of stations, each configured to treat the elongated conductive body. In some of these embodiments, one or more of the stations is configured to coat the elongated conductive body using a meniscus coating process, whereby a solution formed of a polymer and a solvent is prepared, the solution is continuously circulated to provide a meniscus on a top portion of a vessel holding the solution, and the elongated conductive body is advanced through the meniscus. The method may also comprise the step of removing excess coating material from the elongated conductive body by advancing the elongated conductive body through a die orifice. For example, a provided elongated conductive body 510 is advanced through a pre-coating treatment station 520, through a coating station 530, through a thickness control station 540, through a drying or curing station 550, through a thickness measurement station 560, and through a post-coating treatment station 570.

A microfluidic electrochemical device has a microfluidic channel and an electrochemical cell having a pair of working electrodes separated by an inter-electrode distance in a flow direction of the fluid in the microfluidic channel, a counter-electrode and a reference electrode. The microfluidic electrochemical device has an electrochemical amperometry measurement system configured to bias the pair of working electrodes so that each electrode produces an amperometric signal by oxidation reaction or by reduction reaction with the electroreactive fluid or with a chemical species associated with a redox couple intended for the fluid. The microfluidic electrochemical device determines the volume flow rate of the fluid in the microfluidic channel, notably based on the inter-electrode distance and a time delay between the amperometric signals produced by the pair of working electrodes.

An auto-powered biosensor capable detecting a target molecule, and a method of powering the same, wherein the biosensor is fabricated with a microfluidics layer, a multimodal sensing layer comprising a biofuel cell and an electrode, and a logic circuit that may include a processor and non-transitory memory with computer executable instructions embedded thereon.

Skin-mounted or epidermal devices and methods for monitoring biofluids are disclosed. The devices comprise a functional substrate that is mechanically and/or thermally matched to skin to provide durable adhesion for long-term wear. The functional substrates allow for the microfluidic transport of biofluids from the skin to one or more sensors that measure and/or detect biological parameters, such as rate of biofluid production, biofluid volume, and biomarker concentration. Sensors within the devices may be mechanical, electrical or chemical, with colorimetric indicators being observable by the naked eye or with a portable electronic device (e.g., a smartphone). By monitoring changes in an individual's health state over time, the disclosed devices may provide early indications of abnormal conditions.

A flexible, multi-layered device for automatically sensing sweat biomarkers, storing and transmitting sensed data via wireless network to a computing device having software applications operable thereon for receiving and analyzing the sensed data. The device is functional in extreme conditions, including extremely hot temperatures, extremely cold temperatures, high salinity, high altitude, extreme pHs, and/or extreme pressures.

The present subject matter discloses system (100) and method (700) for detecting and monitoring glucose levels. The system (100) comprising wearable device (200) and wearable device (200) comprising a plurality of transceivers (202) configured for transmitting plurality of power packets to one or more transceivers (202) from plurality of transceivers (202) thereby pushing each of, electrolytes under skin (500) of a user, glucose transmitters and glucose molecules towards surface of the skin (500). Plurality of electrodes (204) configured for collecting ions from body section towards the plurality of electrodes (204). Spectroscopic laser (206) and a spectroscopic detector (208) configured for detecting glucose molecules pushed towards surface of the body section. Processor (210) configured for monitoring the glucose levels according to the detection of the glucose levels.

A smart garment includes a garment and a sensor harness attached to the garment. The garment includes an electronic component attachment structure such as a pocket configured to receive an electronic component in a releasable manner. The sensor harness includes an electrical connector component configured to be mechanically and electrically coupled in a releasable manner to an electronic component attached to the garment by the electronic component attachment structure.

Disclosed are novel compositions, devices, patches, systems and methods that are useful for estimating, determining, modulating and/or improving the sleep/wake and/or circadian phase of a subject (e.g., a human subject) by the dispensing of measured quantities of agents to a subject or into an environment of the subject and the continuous monitoring and/or tracking of the subject's consciousness (e.g., sleep/wake) patterns. In certain aspects, the compositions, devices, patches, systems and methods disclosed herein are capable of delivering one or more agents to a subject in response to measured consciousness patterns estimations and circadian phase estimations, thereby aligning the subject's circadian biology to the external environment and improving the quality and duration of sleep.