In some embodiments, a system for providing a therapeutic treatment to a patient's eye includes a treatment beam source configured to transmit a treatment beam along a treatment beam path. The system further includes a processor coupled to the treatment beam source, the processor being configured to direct the treatment beam onto retinal tissue of the patient's eye and deliver a series of short duration pulses from the treatment beam onto the retinal tissue at a first treatment spot to treat the retinal tissue. In some embodiments, a pre-treatment evaluation method using electroretinography (ERG) data may be used to predict effects of treatment beams at different power values and to determine optimal power values.

Various embodiments provide novel tools and techniques for behind-the-car biosignal sensing and stimulation. A system includes a behind-the-car wearable device further including an ear piece, one or more sensors coupled to a patient behind the ears of the patient and a host machine coupled to the behind-the-car wearable device. The host machine includes a second processor, and a second computer readable medium in communication with the second processor, the second computer readable medium having encoded thereon a second set of instructions executable by the second processor to obtain the first signal, separate the first signal into one or more individual biosignals, and determine, based on one or more features extracted from the one or more individual biosignals, awakefulness classification of the patient.

Embodiments of the present disclosure are directed to a wearable phototherapy eye device. In an example, phototherapy can be controlled by varying an emission property of light emitted from the wearable phototherapy eye device to a user eye. In particular, the wearable phototherapy eye device includes a light source oriented to emit the light towards the user eye. The wearable phototherapy eye device also includes controls, such as electrical, mechanical, and/or electro-mechanical controls, to vary the emission property of the light based on an emission target associated with a sleep phase.

Embodiments of the present disclosure are directed to a wearable phototherapy eye device. In an example, phototherapy can be controlled by varying an emission property of light emitted from the wearable phototherapy eye device to a user eye. In particular, the wearable phototherapy eye device includes a light source oriented to emit the light towards the user eye. The wearable phototherapy eye device also includes controls, such as electrical, mechanical, and/or electro-mechanical controls, to vary the emission property of the light based on an emission target associated with a sleep phase.

The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.

The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep.

Apparatus for use in performing electroretinography on a test subject, the apparatus comprising: at least one electrically conductive thread, the at least one electrically conductive thread comprising a first end and a second end, wherein the first end of the at least one electrically conductive thread is configured to mount to skin on one side of an eye of the test subject and the second end is configured to mount to skin on the opposite side of the eye of the test subject, such that the at least one electrically conductive thread is in contact with a surface film of an eye; and an electrically non-conductive coating applied to at least one region of the at least one electrically conductive thread, whereby to electrically isolate the at least one region of the at least one electrically conductive thread from the eye.

Apparatus for use in performing electroretinography on a test subject, the apparatus comprising: at least one electrically conductive thread, the at least one electrically conductive thread comprising a first end and a second end, wherein the first end of the at least one electrically conductive thread is configured to mount to skin on one side of an eye of the test subject and the second end is configured to mount to skin on the opposite side of the eye of the test subject, such that the at least one electrically conductive thread is in contact with a surface film of an eye; and an electrically non-conductive coating applied to at least one region of the at least one electrically conductive thread, whereby to electrically isolate the at least one region of the at least one electrically conductive thread from the eye.

The present disclosure relates to a bioelectrical signal acquisition device, an interactive system, and related methods. The bioelectrical signal acquisition device includes a series of electrodes that are configured and positioned to effectively record bioelectrical signals from a user's head. The interactive system and related methods can be used to collect, display, and analyze the bioelectrical signals, especially signals related to sleep. The device, system, and methods can also be applied to modulate physiological or pathological conditions of the user.

Apparatus and methods are described herein that provide a vibratory device that can apply a vibratory signal to a portion of a head of a user such that the vibratory signal can be conducted via bone to a vestibular system of the user and cause a portion of the vestibular system to move in a manner equivalent to that of a therapeutically effective vibratory signal applied to an area overlaying a mastoid bone of the user. The vibratory device can be associated with frequencies less than 200 Hz. The vibratory device can be effective at treating a physiological condition associated with the vestibular system.