Apparatus for evoking and sensing ophthalmic physiological signals in an eye, the apparatus comprising: an elongated tubular light pipe having a longitudinal axis, a distal end and a proximal end, the distal end terminating in a spheroid recess; an active electrode having a distal end and a proximal end, the active electrode being mounted to the elongated tubular light pipe and extending proximally along the elongated tubular light pipe so that the distal end of the active electrode terminates at the spheroid recess at the distal end of the elongated tubular light pipe; and a reference electrode having a distal end and a proximal end, the reference electrode being mounted to the elongated tubular light pipe and extending proximally along the elongated tubular light pipe so that the distal end of the reference electrode terminates at the spheroid recess at the distal end of the elongated tubular light pipe; wherein the distal end of the active electrode is located closer to the longitudinal axis of the elongated tubular light pipe than the distal end of the reference electrode.

A method for facilitating surgery using an augmented reality system, comprises retrieving patient data relating to a surgical procedure on a patient, generating virtual content comprising a virtual three-dimensional (3D) anatomical model based on the patient data, and displaying the virtual content, such that, when viewed by the first user, the virtual 3D anatomical model appears to be fixed at a physical location, whereby the virtual 3D anatomical model may be viewed by the first user from any angle or orientation merely by walking around the physical location.

A method for facilitating surgery using an augmented reality system, comprises retrieving patient data relating to a surgical procedure on a patient, generating virtual content comprising a virtual three-dimensional (3D) anatomical model based on the patient data, and displaying the virtual content, such that, when viewed by the first user, the virtual 3D anatomical model appears to be fixed at a physical location, whereby the virtual 3D anatomical model may be viewed by the first user from any angle or orientation merely by walking around the physical location.

Device and method for determining an efficacy of chronic pain treatment including providing a first set of at least one stimulus to a subject, obtaining first measurements of at least two physiological parameters in response to the first set of at least one stimulus, providing chronic pain treatment to the subject, providing a second set of at least one stimulus to the subject, obtaining second measurements of the at least two physiological parameters in response to the second set of at least one stimulus; and determining an efficacy of the chronic pain treatment by applying a classification algorithm on the first and second measurements of the at least two physiological parameters.

One embodiment is directed to a system comprising a head-mounted member removably coupleable to the user's head; one or more electromagnetic radiation emitters coupled to the head-mounted member and configured to emit light with at least two different wavelengths toward at least one of the eyes of the user; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering at least one blood vessel of the eye; and a controller operatively coupled to the one or more electromagnetic radiation emitters and detectors and configured to cause the one or more electromagnetic radiation emitters to emit pulses of light while also causing the one or more electromagnetic radiation detectors to detect levels of light absorption related to the emitted pulses of light, and to produce an output that is proportional to an oxygen saturation level in the blood vessel.

One embodiment is directed to a system comprising a head-mounted member removably coupleable to the user's head; one or more electromagnetic radiation emitters coupled to the head-mounted member and configured to emit light with at least two different wavelengths toward at least one of the eyes of the user; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering at least one blood vessel of the eye; and a controller operatively coupled to the one or more electromagnetic radiation emitters and detectors and configured to cause the one or more electromagnetic radiation emitters to emit pulses of light while also causing the one or more electromagnetic radiation detectors to detect levels of light absorption related to the emitted pulses of light, and to produce an output that is proportional to an oxygen saturation level in the blood vessel.

One embodiment is directed to a system comprising a head-mounted member removably coupleable to the user's head; one or more electromagnetic radiation emitters coupled to the head-mounted member and configured to emit light with at least two different wavelengths toward at least one of the eyes of the user; one or more electromagnetic radiation detectors coupled to the head-mounted member and configured to receive light reflected after encountering at least one blood vessel of the eye; and a controller operatively coupled to the one or more electromagnetic radiation emitters and detectors and configured to cause the one or more electromagnetic radiation emitters to emit pulses of light while also causing the one or more electromagnetic radiation detectors to detect levels of light absorption related to the emitted pulses of light, and to produce an output that is proportional to an oxygen saturation level in the blood vessel.

The present invention provides systems, methods, and articles for temperature conditioning a surface. An article is formed from a first layer having a plurality of openings and a second layer having a corresponding plurality of openings. At least one interior chamber constructed and configured to retain a fluid without leaking is defined between an interior surface of the first layer and an interior surface of the second layer. At least one flexible fluid supply line delivers the fluid to the at least one interior chamber. At least one flexible fluid return line removes the fluid from the at least one interior chamber. At least one control unit that is operable to selectively cool or heat the fluid is attached to the at least one flexible fluid supply line and the at least one flexible fluid return line.

Summary The claimed medicament relates to medicine, and it can be used to treat disordered functions of organs or tissues, as well as a wide range of diseases accompanied by disordering of the functions of organs or tissues. The claimed medicament contains the original drug substance or the released-active form of the drug substance treated with bioelectric potentials which have been taken reading from the respective organ or tissue with normal functioning. The pharmaceutical drug substance or the released-active drug substance treated with bioelectric potentials can further be undergo successive multiple dilutions in a solvent selected from the group comprising water and a mixture of water and. The method of obtaining the drug involves exposing the drug substance or the released-active form of the drug substance to bioelectric potentials taken reading from the organ or tissue with normal functioning, with a further, optional successive multiple dilutions in a solvent.

Summary The claimed medicament relates to medicine, and it can be used to treat disordered functions of organs or tissues, as well as a wide range of diseases accompanied by disordering of the functions of organs or tissues. The claimed medicament contains the original drug substance or the released-active form of the drug substance treated with bioelectric potentials which have been taken reading from the respective organ or tissue with normal functioning. The pharmaceutical drug substance or the released-active drug substance treated with bioelectric potentials can further be undergo successive multiple dilutions in a solvent selected from the group comprising water and a mixture of water and. The method of obtaining the drug involves exposing the drug substance or the released-active form of the drug substance to bioelectric potentials taken reading from the organ or tissue with normal functioning, with a further, optional successive multiple dilutions in a solvent.