A system and method for non-invasive and/or non-contact measurement of a subject's tremor in the context of therapeutic intervention is presented. The system includes a memory, a communications interface, a sensor to measure a signal associated with position or motion of an extremity of the subject, and a processor. The processor is configured to receive the signal from the sensor. The processor is further configured to communicate, via the communications interface, the signal, login credentials, and position or motion data to a remote server coupled to a remote electronic health record database. The remote server is configured to receive the signal and perform an analysis that quantifies a severity of tremor based on the position or motion signals of the subject. The processor is configured to receive the analysis that quantified the severity of tremor and cause the quantified severity of tremor to be displayed via a display device.

A system for monitoring neural activity of a living subject is provided. The system may comprise a correspondence module configured to be in communication with (1) a neural module and (2) one or more additional modules comprising a sensing module, another neural module, and/or a data storage module. The neural module(s) are configured to collect neural data indicative of perceptions experienced by the living subject. The sensing module may be configured to collect (1) sensor data indicative of real-world information about an environment around the living subject, and/or (2) sensor data indicative of a physical state or physiological state of the living subject. The data storage module may be configured to store prior neural data and/or prior sensor data. The correspondence module may be configured to measure a correspondence (a) between the neural data collected by the neural module(s) and the sensor data collected by the sensing module, (b) between the neural data collected by two or more neural modules, and/or (c) between the neural data collected by the neural module(s) and the prior data stored in data storage module. The measured correspondence can be used to determine a presence, absence, or extent of a potential cognitive or physiological disturbance of the living subject.

Disclosed here are methods and systems for assessing an emotional response of a subject or a group to a sensory stimulus. The methods employ models that infer emotional response based on individual traits of subjects or groups.

A system and method for screening a subject for a pupillary response to an olfactory stimulus as an indication for COVID-19. The method can include providing the olfactory stimulus to the subject via a scent dispenser, measuring a pupillary response of the subject to the olfactory stimulus via a detector, and comparing the measured pupillary response to a reference. The reference could include a default value or a characterized pupillary response for the subject or a population of individuals to the olfactory stimulus. The method can further include determining whether the subject demonstrates a diminished or an absent response to the olfactory stimulus according to whether the measured pupillary response differs from the reference by a threshold and providing an alert accordingly. The alert can include an intervention associated with COVID-19, such a recommendation to seek medical evaluation or take a COVID-19 diagnostic test.

An electrospray ionization olfactometer device, method and system for vaporizing aroma compounds for the purpose of psychophysical experimentation and sensory evaluation are provided.

An access system has a scanner that scans a unique identifier to access a location. A display receives an input. An automated dispenser dispenses at least one scent on each hand of an individual responsive to a control signal. A processor controls access to the location. A memory stores a set of instructions that configures the processor to receive the unique identifier from the scanner, actuate the automated dispenser to dispense the at least one scent responsive to receipt of the unique identifier, receive the response input based on the scents detected by the individual of the at least one scent, determine a passing result or a failing result responsive to the received response input and an expected response based on the dispensed at least one scent, enable access to the location responsive to a passing result and deny access to the controlled access location responsive to a failing result.

The present disclosure relates to the field of brainwave technology, and provides a detection device and a detection method. The detection device includes: a brainwave acquisition circuit configured to collect a brainwave signal of a user in the case that a distance between the user and a to-be-detected object is smaller than a threshold; and a processing circuit configured to process the collected brainwave signal to acquire brainwave information, and acquire a detection result of the to-be-detected object in accordance with the brainwave information. The brainwave information includes at least one of olfactory information and gustatory information of the user.

Many factors contribute to dogs' superior olfactory capabilities as compared to humans. Studies explored this aspect at the cellular and behavior levels; however, the cognitive-level neural substrates linking them have never been explored. Since sedated dogs cannot sniff, the present application illustrates the cognitive-level linking neural substrate using fMRI of conscious dogs. The head motion of the canine is accounted for by behavioral training and optical motion tracking. The olfactory bulb is commonly activated in both awake and anesthetized dogs, while parietal and frontal structures are activated only in the former and subcortical structures only in the latter. Comparison of low and high odor intensity shows differences in both the strength and spatial extent of activation in higher cognitive structures. Unlike humans, neural structures even at the top of the cognitive hierarchy are modulated by odor concentration in dogs. This represents one possible mechanism for their superior sense of olfaction as compared to humans.

Disclosed are compositions and methods for measuring olfactory sensitivity, olfactory resolution, and combinations thereof. Such measurements can be made during a single test, or over consecutive tests, which may be performed during a single testing period, such as in a single day, or over a series of testing periods. The tests may be performed by a health care professional, or may be conveniently self-administered by the user.

A hand held olfactory tester includes an elongated housing (12) with an opening at its forward end (30) thereof. An odorant chamber (22) located within the housing moveable axially between a forward (FIG. 4) and a backward position (FIG. 5). A wick (34) extends from the odorant chamber forwardly into a nozzle (32) carried at the forward end of the chamber. A thumb collar (24) located around the outside of the housing allows to move the odor chamber and nozzle forwardly. The forward end of the wick exposed to outside through the opening when moved forward so that vapors from the odorant can be smelled by a patient. O-rings (40, 42) seal the nozzle from the outside when in backward position to prevent vapors from escaping. An elongated spring (28) biases the odorant chamber and nozzle backwardly into its rear sealed position when the thumb collar is released.