Methods of restoring homeostatic capacity of a subject are provided. Aspects of the invention further include compositions, systems and devices for practicing the methods. The methods and compositions described herein find use in a variety of applications. Aspects of certain embodiments of the methods include modulating a subject's autonomic nervous system in a manner sufficient to restore the homeostatic capacity of the subject. Aspects of other embodiments of the invention include administering to the subject an amount of an apoptosis modulator effective to at least partially restore homeostatic function of the neuroendocrine system of the subject.

A blood glucose measurement apparatus includes: a control unit configured to determine a user's blood glucose level based on a concentration of body fluid secreted from the user; and a biometric information acquisition unit configured to acquire biometric information indicating a status of a user's autonomic nervous system. The control unit is configured to correct the determined blood glucose level based on the biometric information.

An apparatus includes a posture sensing circuit configured to detect a change in posture of a subject; a cardiac signal sensing circuit configured to generate a sensed cardiac signal, wherein the sensed cardiac signal includes heart rate information of the subject; a physiologic sensing circuit configured to generate a sensed physiologic signal, wherein the physiologic signal includes information related to blood pressure of the subject; a storage buffer; and a control circuit operatively coupled to the posture sensing circuit and the storage buffer. The control circuit is configured to initiate storage of the heart rate information and the information related to blood pressure in response to a detected change in posture of the subject.

Systems and methods for assessing sympathetic nervous system (SNS) tone for renal neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a detector attached to or implanted in a patient and a receiver communicatively coupled to the detector. The detector can measure cardiac data and the receiver and/or a device communicatively coupled thereto can analyze the cardiac data to provide one or more SNS tone indicators. The SNS tone indicators can be used to determine whether a patient will be responsive to a neuromodulation therapy and/or whether a neuromodulation therapy was effective.

An information processing apparatus according to the present technology includes a processing section that executes a process including a correction process of specifying noise included in perspiration data acquired by a perspiration sensor on a basis of sensor data acquired by a different type of sensor than the perspiration sensor, and removing the noise from the perspiration data. According to such a technology, noise estimated according to other sensor data can be removed from the perspiration data, making it possible to maintain high accuracy in a later process of estimating activity in the autonomic nerves.

Described herein are forehead-mounted temperature regulation apparatuses and methods of using them. These apparatuses may be used for improving sleep. Also described herein are methods of improving sleep using these apparatuses.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect mood, focus, and cognition of subjects.

A modular, multi-modal energy therapy system for electrical and electromagnetic stimulation includes signal generating, conditioning, and control electronics, stimulation monitoring electronics, signal conduits, and wearable energy emitter modules configured for coupling energy emitters to surfaces of the human ear for transcutaneous energy delivery to nerves in the auricular nerve field. Electrical emitter modules configured with electrodes deliver electrical stimulation; electromagnetic emitter modules configured with light emitting diodes deliver electromagnetic stimulation. A computer controls signal generating electronics and provides internet connectivity with a remote server. Application software includes stimulation programming and parameter selection, and databases containing user data, records of stimulation sessions, user responses to symptom assessment instruments, and biofeedback sensor input enable local and remote monitoring of a user's health status by therapists.

Methods and apparatuses for stimulation of the vagus nerve to treat inflammation including adjusting the stimulation based on one or more metric sensitive to patient response. The one or more metrics may include heart rate variability, level of T regulatory cells, particularly memory T regulatory cells, temperature, etc. Stimulation may be provided through an implantable microstimulator.

A computer-implemented system for training a subject to improve psychophysiological function for performance of stress-inducing activity includes a sensor interface device and a non-transitory, tangible computer readable storage medium storing computer program code. The sensor interface provides measurement of a physiological parameter of the subject, indicating stress in the subject.

The computer readable storage medium stores computer code that provides a set of training segments presenting the subject with one or more visual, audible, or tactile prompts wherein at least one of the training segments simultaneously presents the subject with a stress-inducing prompt while inducing the subject to perform a relaxation-inducing protocol.