The present invention provides systems and methods for monitoring cardiac autonomic nervous system activity and modulating parasympathetic control of cardiac function.

An information processing device is provided that includes a display and a processor configured to acquire vital data regarding a creature and cause the display to display an image in which data regarding the creature at a plurality of time points are plotted on a graph having an abscissa axis and an ordinate axis one of which represents an autonomic nervous balance of the creature and another represents a numerical value based on the vital data of a type that differs from the autonomic nervous balance of the creature.

Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including a head mounted display to monitor one or more physiologic signals from the face or head of the subject is disclosed. A method for analyzing an ocular parameter of the subject to determine a sympathetic and a parasympathetic outflow thereto is disclosed.

A system for electro-therapeutically treating a patient includes a stimulatory device electromagnetically coupled with the nervous system of a patient, an electrical power supply, and a control mechanism structured to energize the stimulatory device by way of the electrical power supply at a stimulation frequency. The control mechanism is further structured to control the energizing so as to produce a treatment signal encoded in the energizing and having a treatment signal frequency equal to or less than the stimulation frequency.

Provided is a monitoring apparatus, a monitoring method, and a monitoring program that can support health management of a user. A monitoring apparatus comprises: an acquisition unit configured to acquire biological information of a subject; a controller configured to determine whether the subject has disease development risk, based on a result of analyzing the biological information of the subject; and a notification interface configured to notify information about the disease development risk.

An example computer readable storage medium having stored thereon an information processing program executable by a computer of an information processing device which presents information corresponding to a biological signal acquired from a user, is provided. The information processing program causes the computer to function as biological signal acquiring means, motion/attitude information acquiring means, and presentation means. The biological signal acquiring means acquires the biological signal from the user. The motion/attitude information acquiring means acquires information about a motion or an attitude of the user from detecting means, in association with the biological signal acquired by the biological signal acquiring means. The presentation means performs predetermined presentation based on both the biological signal acquired by the biological signal acquiring means and the information acquired by the motion/attitude information acquiring means.

Systems and methods for treating a patient having acute decompensated heart failure (ADHF) using electrical stimulation are disclosed. A representative method for treating a patient includes positioning an implantable signal delivery device proximate to a target location at or near the patient's spinal cord within a vertebral range of about T1 to about T12, directing an electrical therapy signal to the target location via the implantable signal delivery device, wherein the electrical signal has a frequency in a frequency range of from 1.2 kHz to 100 kHz to modulate one or more of the patient's sympathetic nerves and treat the patient's ADHF.

Methods for caring for a patient are disclosed. In some embodiments, the methods include measuring a first autonomic nervous system condition of the patient, calculating a first autonomic dysfunction based on the measured first autonomic nervous system condition, and calculating a first sympathovagal balance based on the first measured autonomic nervous system condition. The method also includes treating the patient, measuring a second autonomic nervous system condition of the patient, calculating a second sympathovagal balance based on the second measured autonomic nervous system condition, and comparing the second sympathovagal balance with the first sympathovagal balance. The method also includes calculating a second autonomic dysfunction based on the measured second autonomic nervous system condition, and comparing the second autonomic dysfunction with the first autonomic dysfunction.

A method of improving psychophysiological function of a subject performing a stress-inducing activity using a computer includes, after a plurality of sensors that monitor stress-indicating physiological parameters have been coupled to the subject and to the computer, providing, by the computer to the subject, a set of training segments that each present the subject with one or more visual, audible, or tactile prompts, wherein in at least one of the training segments, the prompts induce the subject to simultaneously perform both the stress-inducing activity and a relaxation-inducing protocol. The computer provides the set of training segments until a value of at least one physiological parameter that indicates stress in the subject is within a pre-defined range of a baseline value of the parameter, thereby indicating that the subject has successfully performed the stress-inducing activity while maintaining alertness with a relative minimum of stress.

The present invention teaches a method and apparatus for physiological modulation, including neural, gastrointestinal, renal, respiratory, and other modulation, for the purposes of treating several disorders, including obesity, depression, epilepsy, diabetes, hypertension, asthma, and other disorders. This includes implanted, percutaneous, hybrid implanted and nonimplanted, nonimplanted, noninvasive neural and neuromuscular modulators, used to deliver autonomic vector modulation to deliver optimal therapy via coordinated multi-nodal modulation at least one of the afferent and efferent neurons of the sympathetic and parasympathetic nervous systems and other nervous system pathways.