A system and methods utilizing electrical stimulation to achieve a desired therapeutic effect are provided. In one aspect, a method for controlling nerve activity in a subject is provided. The method includes receiving input indicating a desired therapeutic effect for at least one neural structure of a subject, and selecting, based on the input received, an electrical stimulation configured to achieve the desired therapeutic effect. The method also includes controlling a sympathetic nerve activity in the subject by delivering the electrical stimulation using electrodes positioned proximate to nerves innervating the subject's skin.

A biological information acquisition device includes a body motion detector that includes a pressure sensitive portion on which a body motion of a subject acts and that detects a signal indicating the body motion of the subject, and a clamp member that clamps a clothing item of the subject. The clamp member includes a first member that is disposed on the subject side of the clothing item, and a second member that is disposed on the opposite side of the clothing item from the first member. The pressure sensitive portion is disposed on the first member side.

A system and method of monitoring the health of a person. The system comprises at least one sensor capable of measuring at least one physiological signal generated by the autonomic nervous system of the person for providing measurement data, and a data processing system which is configured to store a reference indicator, to receive measurement data from the sensor during a plurality of consecutive health-maintenance sessions in order to collect a plurality of measurement data sets corresponding to said health-maintenance sessions, to determine at last one health indicator based on the measurement data sets, said at least one health indicator being sensitive to physiological state of or changes in the autonomic nervous system, and to compare the at least one health indicator with said reference indicator. Objective information on autonomic nervous system related dysfunctions is retrieved which allows for systematic treatment to the person.

A stress state evaluation apparatus includes an acquisition section that acquires living body data from each individual included in a group, a first specification section that specifies a non-stress state of each individual based on the living body data acquired from the acquisition section, an adjustment section that adjusts a determination reference of a stress state of each individual based on the non-stress state of each individual specified in the first specification section, a second specification section that specifies the stress state of each individual using the determination reference adjusted by the adjustment section based on the living body data acquired from the acquisition section, and an operation section that operates a stress state of the group based on the stress state, which is specified by the second specification section, of each individual.

A stress level monitoring system includes a controller and a pulse oximeter electrically coupled to the controller. The pulse oximeter measures a photoplethysmograph signal. The controller determines a stress level of a patient from the photoplethysmograph signal.

A system and method for training program generation and modification based on user input goal data and assessed functional state and/or workload performance. A user-interface preferably operating on a mobile device permits a user to record bio-signals indicative of functional state. Assessments are performed on the received bio-signal data to produce training session targets based on the current functional state of the user. Workload performance may be monitored and the training session targets modified based on measured past performance to improve future performance. Various embodiments are disclosed.

Devices, systems and methods for treating medical disorders, such as migraine or other primary headaches, or fibromyalgia, by noninvasive electrical stimulation of a vagus nerve, used in conjunction with the measurement of evoked potentials (EPs). The system comprises a stimulator that is applied to the surface of the patient's neck to apply electrical impulses sufficient to stimulate a cervical vagus nerve, scalp electrodes that are used to measure EPs that are evoked by that stimulation, feedback or biofeedback circuits to vary the stimulation based upon EP characteristics, and other sensory stimulation modalities that produce EPs. The system is preferably used to optimize the placement of the stimulator, to test whether a patient is a suitable candidate for treatment using vagus nerve stimulation, and to select the stimulation parameters that optimized acute or chronic treatment, e.g., by correcting an EP habituation deficit.

The present invention provides devices and methods that can prevent or ameliorate bronchoconstriction by stimulating neural activity, in contrast to those techniques based on denervation, ablation or blocking of neural activity. Methods and devices according to the invention may act responsively or on demand, can preserve neuronal structure and function and will be associated with minimal collateral side-effects. In particular, the invention provides devices and methods in which signals are delivered to the vagus nerve in order to stimulate neural activity in the vagal nerve.

Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including a head mounted display to monitor one or more physiologic signals from the face or head of the subject is disclosed. A method for analyzing an ocular parameter of the subject to determine a sympathetic and a parasympathetic outflow thereto is disclosed.

The present disclosure relates to measuring recovery of a finger skin temperature of a writing instrument's user, comprising: measuring a first finger skin temperature of a user's finger contacting a grip area of the writing instrument during a writing session with the writing instrument; cooling the finger contacting the grip area with a cooling element and for a cooling duration; measuring a second finger skin temperature after lapse of the cooling duration; calculating the skin temperature reduction; measuring a series of finger temperature measurements after lapse of the cooling duration; calculating a temperature recovery rate based on the series of finger temperature measurements; comparing the skin temperature reduction and the temperature recovery rate to historical data and/or reference data; and providing an indication to the user in case that the skin temperature reduction and/or the temperature recovery rate are abnormal as compared to the historical data and/or reference data.