Devices, systems, and methods for auto-retroperfusion of the cerebral venous system. In an exemplary embodiment of a catheter for controlling blood perfusion pressure of the present disclosure, the catheter comprises a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen and adapted to move between an expanded configuration and a deflated configuration, and at least one sensor coupled with the distal end of the body, each of the at least one sensors adapted to gather data relating to a fluid flowing through the lumen, wherein the catheter is configured to be coupled to a flow unit for regulating the flow and pressure of a fluid.

A method for identifying an occurrence of a concussion in a subject involves capturing eye blink raw data from at least one eye of the subject. The method next involves analyzing the eye blink raw data to generate at least a first subject specific eye blink metric and determining that a significant difference exists between the first subject specific eye blink metric and a predefined normal value. Next, the occurrence of the concussion in the subject may be identified, based on determining that the significant difference exists.

Systems, apparatuses, methods, and non-transitory computer-readable media for mapping a section of a vasculature of a subject are described herein, including moving a probe to a first position at a body of the subject adjacent the section of the vasculature; transmitting, by the probe, a first ultrasound beam into a first portion of the section of the vasculature through the body of the subject; receiving first ultrasound data including at least one imaging parameter of the first portion based on the first ultrasound beam; moving the probe to a second position at the body of the subject adjacent the section of the vasculature and different from the first position; transmitting, by the probe, a second ultrasound beam into a second portion of the section of the vasculature through the body of the subject; receiving second ultrasound data including the at least one imaging parameter of the second portion based on the second ultrasound beam; and constructing a map of the section of the vasculature based on the first ultrasound data and the second ultrasound data.

Methods and system for assessment of a state of the central nervous system (CNS) of a subject and/or differentiation between states of the CNS at a specific time point based on electrophysiological recordings of signals from at least two anatomical structures, wherein the signals are recorded from recording sites located in the anatomical structures, wherein the electrophysiological recordings comprise spatiotemporal fluctuations in the recorded extracellular potential, wherein the electrophysiological recordings are action potentials and/or local field potentials (LFPs) in the anatomical structures and represent the state of the CNS, a s well as the use of the method for assessment of a state of the CNS and/or differentiation of at least two states of the CNS, as well as to the use of the method for evaluating the effect of a treatment of a condition or disease, wherein the condition or disease is neurological and/or psychiatric.

A method of providing a channel in nervous tissue filled with an aqueous gel for implantation of a microelectrode or other medical device lacking sufficient physical stability for direct implantation by insertion, comprises providing an apparatus comprising an oblong rigid pin covered by a dry gel forming agent; locating a target in the tissue; defining a straight insertion path a desired tissue insertion point and the target; aligning the pin with its end foremost with the insertion path; inserting the pin into the tissue to a position near or at the target; allowing sufficient time to pass for a gel to be formed around the pin, withdrawing the pin. Also disclosed is a corresponding channel; a method of implantation of a microelectrode or microprobe into nervous tissue via the channel; a corresponding method of implantation of living cells; a corresponding apparatus for forming the channel.

A method for estimating a likelihood of a stroke condition of a subject, the method comprising: acquiring clinical measurement data pertaining to said subject, said clinical measurement data including at least one of image data, sound data, movement data, and tactile data; extracting from said clinical measurement data, potential stroke features according to at least one predetermined stroke assessment criterion; comparing said potential stroke features with classified sampled data acquired from a plurality of subjects, each positively diagnosed with at least one stroke condition, defining a positive stroke dataset; and determining, according to said comparing, a probability of a type of said stroke condition, and a probability of a corresponding stroke location of said stroke condition with respect to a brain location of said subject.

A method for performing cellular classification includes generating a plurality of local dense Scale Invariant Feature Transform (SIFT) features based on a set of input images and converting the plurality of local dense SIFT features into a multi-dimensional code using a feature coding process. A first classification component is used to generate first output confidence values based on the multi-dimensional code and a plurality of global Local Binary Pattern Histogram (LBP-H) features are generated based on the set of input images. A second classification component is used to generate second output confidence values based on the plurality of LBP-H features and the first output confidence values and the second output confidence values are merged. Each of the set of input images may then be classified as one of a plurality of cell types using the merged output confidence values.

The present invention provides a system and method for collection, storage and processing of tissues and cells. The system includes a collection container with chambers for storing and processing tissues, which are controllably separated and maintain a physiologic environment for the tissues. The system also includes a fluidic device for isolating target cells of interest. The method includes receiving the tissue into a collection chamber, transferring the tissue to a processing chamber, dissociating the tissue into single cells, and passing the single cells to a device for isolating one or more target cells.

A method and a system for detecting the possible existence of a stroke is provided. In a first step of the method, a first measurement of a nerve impulse is obtained from the skin of a first location of a patient using a magnetometer. In a second step, the first measurement is compared with either a baseline measurement or a second measurement of a nerve impulse obtained from the skin of a second location of the patient using a magnetometer. In a third step, a signal is transmitted indicating a possible stroke if there is no symmetry between the first measurement and either the baseline measurement or the second measurement.

An information processing apparatus according to an embodiment includes a processing circuit. The processing circuit acquires a measurement field corresponding to a spatial distribution of a predetermined physical quantity in a subject of measurement. The processing circuit calculates an unknown quantity in the subject of measurement based on a first equation between the measurement field and the unknown quantity having spatial dependence, and on the acquired measurement field. The first equation is one that is acquired based on a second equation expressing a dual field divergence of which can be expressed using the measurement field, by using the measurement field and the unknown quantity, and on the Helmholtz decomposition of the dual field.