The present invention relates to an immunoglobulin therapy. In particular, an immunoglobulin therapy for treating CIDP with non-axonal damage or mild axonal damage is provided.

A system provides a burr hole cap assembly configured to secure a position of a lead implanted through a burr hole in a cranium of a patient. One or more electrodes are coupled to one or more components of the burr hole cap assembly. The one or more electrode is disposed within the burr hole cap assembly for sensing signals within a brain of the patient or stimulating a portion of the brain of the patient.

A wearable device comprising a data logger, a motion sensor, and a memory component is disclosed for recording motion data. The motion sensor may detect movement of the device when worn by a subject, and the memory component may store motion data from the motion sensor. A casing may be included for retaining the data logger and providing a contact barrier between at least part of the data logger and the subject. The contact barrier may substantially prevent contact contamination of at least part of the data logger while the device is worn by the subject for collection and storage of subject-specific motion data. The casing is controllably accessible to release the data logger in a substantially uncontaminated state.

The presently disclosed subject matter relates to a play environment for children and infants for detecting motor delays or impairments, evaluating neurological development, and for diagnosing developmental disorders, and methods and systems of using the same.

This disclosure relates to a device to mechanically and electrically connect with a touch screen computing device, such as a tablet computer. The device can include a platform that can be moved into and out of physical contact with a surface of a touch screen. During engagement with the surface, the moveable platform electrically interacts with the touch screen (e.g., via capacitive coupling) to enable detection by the touch screen of contact members (e.g., pegs) even in the absence of user contact with the pegs.

A system for measuring and monitoring physiologically relevant motion of a subject includes at least a motion sensor to measure movement of the subject and produce a series of movement data representing the movement of the subject over a period of time. The system also includes at least a biometric sensor to simultaneously measure biometrics of the subject and produce a series of biometric values of the subject over the period of time. The system is configured to determine a noise-to-signal ratio for the series of movement data as a function of biometric intervals in the series of biometric values and identify at least a portion of the series of movement data as corresponding to a physiologically relevant biorhythm. The system can be used to diagnose and monitor a disease or disorder, including a neurological disorder or a traumatic brain injury.

Disclosed is system for assessing a motor function, the system including a sensor configured to acquire human body exercise information including a joint position, a joint orientation, a grasp state, or a grasp force, a processor configured to extract an exercise feature for analyzing a human body motion time and human body motion information based on the acquired human body exercise information, analyze at least one target motion for assessment based on a set assessment condition using the extracted exercise feature, classify an assessment factor of the at least one target motion for assessment as a success or a failure, and determine a final assessment score of the at least one target motion for assessment based on the classified assessment factor, and a display configured to display the final assessment score.

An apparatus for simulating hand tremors caused by Essential Tremor and Parkinson's disease which may also be used as part of a therapeutic program in association with surgically implanted stem cells introduced into a patient's substantia nigra.

A wearable device comprising a data logger, a motion sensor, and a memory component is disclosed for recording motion data. The motion sensor may detect movement of the device when worn by a subject, and the memory component may store motion data from the motion sensor. A casing may be included for retaining the data logger and providing a contact barrier between at least part of the data logger and the subject. The contact barrier may substantially prevent contact contamination of at least part of the data logger while the device is worn by the subject for collection and storage of subject-specific motion data. The casing is controllably accessible to release the data logger in a substantially uncontaminated state.

Design and development of an affordable, user-friendly, and portable POCT hand tremor detection device has been reported. This device is composed of a detection unit, a flexible pressure sensor, a signal processing unit, and a power supply. The detection unit is composed of the sensor and press-knob. The flexible pressure sensor is a combination of usually spaced apart flexible polymer preferably polydimethylsiloxane, flexible substrate preferably paper, and a conductive coating preferably reduced graphene oxide (RGO). When the users put pressure on the press-knob through the fingers, the flexible pressure sensor actuates and bends so that conductive RGO layers on the flexible substrates come in contact with each other to generate an output current. The electrical circuits in the signal processing unit are laid down in such a manner that the magnitude of this output current varies with the tremor between the fingers, which eventually converted into an electrical signal showing the variation in the hand tremor with time. The proposed POCT device is wirelessly connected to an android mobile application to measure the hand tremors for a longer period of time, display on the mobile interface, and store the data for future analysis of the neurological disorders. The proposed POCT device has the capability to detect the neurological disorders at the mature as well as at the early stages with the vision of control and prevention of these diseases.