The present invention relates to a system (10) for supporting an elderly, frail and/or diseased person (12), in particular a person suffering from Parkinson's disease, wherein the system (10) comprises: a detection unit (14) including (i) a brain activity sensor (20) for detecting a brain activity signal relating to the brain activity of the person (12) and (ii) a motion detection unit (22) for detecting a motion signal relating to a motion of one or more body parts of the person (12); an analysis unit (16) for determining, based on the detected brain activity signal and motion signal, an activity level of the person (12) which is indicative of the motoric and cognitive activity of the person (12); and a feedback unit (18) for providing a feedback to the person (12) if the activity level of the person (12) exceeds a predetermined threshold.

In one aspect, the invention comprises an implantable living electrode comprising a substantially cylindrical extracellular matrix core; one or more neurons implanted along or within the substantially cylindrical extracellular matrix core, the one or more neurons including one or more optogenetic or magnetogenetic neurons proximal to a first end of the implantable living electrode.

The present invention relates to systems and methods for helping subjects improve safety and efficiency of their movements; particularly subjects who have suffered an injury or suffer from a movement or other such disorder. More particularly, the present invention relates to such a system and method for monitoring a subject's movement to detect or predict unsafe, undesirable, or impaired movements, or symptoms of movement disorders, and also a system for providing possible treatment methods for such conditions. The present invention further relates to a method and system of providing cues or stimuli to the subject when such unsafe or undesirable movements, instabilities or symptoms are detected or predicted. Most particularly, the present invention relates to a subject-customized and adaptive movement recovery system, and method of providing therapy and training to improve functional motor recovery and safety of movement of a subject suffering from an injury or from movement disorder(s).

Monitoring brain neural activity comprises repeatedly applying electrical stimuli to evoke neural responses in the brain. Neural responses evoked by the stimuli are recorded. The recorded neural responses are assessed for changed characteristics over time, to monitor a time-varying effect on the recorded neural responses of local field potentials arising from a source other than the electrical stimuli.

Fitting a brain neurostimulator electrode array comprises positioning at least a first electrode in a desired target structure in a first cerebral hemisphere, and positioning at least a second electrode in a corresponding target structure in a contralateral cerebral hemisphere. Electrical stimuli are applied from the first electrode to the desired target structure. Neural responses observed at the second electrode in response to the electrical stimuli are recorded. The fitting of at least one of the first electrode and second electrode is assessed by reference to the recorded neural responses.

A medical evaluation system includes an I/O module, a processing module, and an analysis module. The I/O module receives sensory data obtained by a motion sensor disposed in a mobile device carried by a patient at least when the patient is in a non-clinical environment. The processing module extracts medically relevant data from the sensory data received from the sensor in the mobile device. The relevant data includes one or more features of interest in the sensory data. The analysis module derives one or more surrogate biomarkers from the relevant data. The surrogate biomarkers represent at least one of a state or a progression of a medical condition of the patient. The mobile device may be a mobile phone carried by the patient and the sensor may include at least one of an accelerometer or a gyroscope that generates the sensory data to represent movements of the patient.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia. Described are methods and devices to treat coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect symptoms of coma, post-traumatic stress disorder, Parkinson's disease, cognitive performance, and/or amblyopia.

Disclosed is system for assessing a motor function, the system including a sensor configured to acquire human body exercise information including a joint position, a joint orientation, a grasp state, or a grasp force, a processor configured to extract an exercise feature for analyzing a human body motion time and human body motion information based on the acquired human body exercise information, analyze at least one target motion for assessment based on a set assessment condition using the extracted exercise feature, classify an assessment factor of the at least one target motion for assessment as a success or a failure, and determine a final assessment score of the at least one target motion for assessment based on the classified assessment factor, and a display configured to display the final assessment score.

System and method for diagnosing brain conditions including evaluating fiber pathways of white matter tracts using a diffusion tensor imaging (DTI) process, tracking the propagation of waves traveling at specific angles to the fiber pathways by performing a 3D magnetic resonance elastography (MRE) process at the same spatial resolution and voxel position as the DTI, analyzing the viscoelastic properties using an inversion having at least nine elastic coefficients, determining the curvature along the pathways, differentiating the spatial-spectral filter twice with respect to arc length along the pathways, and diagnosing a brain condition based on the viscoelastic properties.

A method includes measuring, using at least one sensor, strain on a nail plate of a subject, wherein the at least one sensor outputs a data stream corresponding to the measuring, communicating the data stream to a receiver, and interpreting, by the receiver, the data stream to determine a parameter of interest of the subject.