An example computer-implemented method for analyzing skin of a user comprises requesting, via a graphical user interface (GUI), visual media including a face of the user, processing the visual media to generate information for each of a plurality of skin conditions of the face of the user and the information comprises a score per each of a plurality of zones of the face of the user per each of the plurality of skin conditions of the face of the user, mapping the score to a severity level associated with the plurality of skin conditions, and for each of the plurality of skin conditions, the GUI overlaying computer graphics at locations onto the visual media corresponding to the plurality of zones of the face of the user. The computer graphics are depicted with a color associated with the severity level for the skin condition at each of the locations.

An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.

The present disclosure relates to plasma generation systems which utilize plasma for semiconductor processing. The plasma generation system disclosed herein employs a hybrid matching network. The plasma generation system includes a RF generator and a matching network. The matching network includes a first-stage to perform low-Q impedance transformations during high-speed variations in impedance. The matching network includes a second-stage to perform impedance matching for high-Q impedance transformations. The matching network further includes a sensor coupled to the first-stage and the second-stage to calculate the signals that are used to engage the first and second-stages. The matching network includes a first-stage network that is agile enough to tune each state in a modulated RF waveform and a second-stage network to tune a single state in a RF modulated waveform. The plasma generation system also includes a plasma chamber coupled to the matching network.

An imaging device that images a disease site as a subject includes a camera body, a light unit that is provided in the camera body and includes a first light source and a second light source that have different characteristics, and a filter unit that includes at least one independent filter capable of being positioned on and retracted from an optical axis of the camera body. The imaging device performs continuous imaging by imaging in a state in which the subject is illuminated with light from the first light source and, via a first mode, the filter is positioned on or retracted from the optical axis and, thereafter, imaging in a state in which the subject is illuminated with light from the second light source and, via a second mode that differs from the first mode, the filter is positioned on or retracted from the optical axis.

In some embodiments, a computer-implemented method of generating a visualization of wavelength-dependent surface characteristics is provided. A computing device receives an input image captured by a camera, wherein the input image includes information in a low-dimensional color space. The computing device processes the input image to determine spectrum band information in a high-dimensional color space that corresponds to the input image. The computing device extracts subtractive information from the spectrum band information to obtain wavelength-dependent surface characteristic information, The computing device generates the visualization using the wavelength-dependent surface characteristic information. In some embodiments, the computing device may be a smartphone.

Instruments and methods for wide-field polarized imaging of the skin to determine an outer lesion margin objectively in vivo to provide guidance to a surgeon. Quantitative characterization of collagen structures in the skin can be used to determine the outer lesion margin or monitor skin treatment.

An etalon-based mid-infrared probe can be configured for spectroscopic tissue discrimination, such as between non-normal (e.g., cancerous) and normal (e.g., healthy) tissue. A broadband light source can be applied to the etalon to generate fringes at spectroscopic wavelengths of interest, which can be delivered to a tissue specimen via a fiber loop probe. A response signal can be spectral dispersed across a parallel array of detector pixels, such as using a diffraction grating, and signal processed for performing the tissue classification. A learning model can be trained, using full IR spectral data, for applying a reduced set of wavelengths for performing the spectroscopic tissue analysis and classification.

An optical system for the detection of skin disease, such as melanoma, acquires images of a lesion on a subject's skin at different wavelengths and utilizes a sweeping arm rotating about the lesion in a clock-like sweep to produce diagnostically relevant metrics and classifiers from the image data so as to enhance detection of the skin disease.

Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).

A surface of the tissue is illuminated with light having a known wavelength spectrum capable of materially penetrating the tissue. The light remitted from the tissue in response to the illumination is separated into at least two distinguishable polarization components. The intensity of the illumination light remitted from the tissue is measured over a hyperspectral range of wavelengths for the at least two distinguishable polarization components. Based on the preceding measurements and a degree of linear polarization of the remitted light, data representative of the three-dimensional location and one or more characteristics of an abnormal portion of the tissue are produced. Further, the masking effect of melanin may be eliminated to obtain accurate estimations of an anomaly.