An occluder and an occlusion device, including: a mesh occlusion body, which defines a cavity, and a proximal end bolt head; the proximal end bolt head configured with a locking hole which penetrates the cavity; the occluder further having a locking member, a distal end of the locking member being connected to a distal end of the occlusion body; the locking member having a connecting portion which is connected to the occlusion body; the diameter of a circumscribed circle of a projection of the first bending portion on a cross section perpendicular to a length direction thereof being smaller than the diameter of the smallest inscribed circle of a locking hole, and the width of a projection of the first bending portion on a plane perpendicular to longitudinal central axis direction of the locking hole being larger than the diameter of the largest inscribed circle of the locking hole.

A lock for positioning a first medical device with respect to a second medical device includes a spacer for preventing advancement of the first medical device towards the second medical device. The spacer is movable between a lock position and an unlock position. In the lock position, the spacer is moved transverse to the longitudinal axis with respect to the unlock position. The lock further includes a rotary stop integral with the spacer for fixing the rotational position of the first medical device with respect to the second medical device. The lock further includes a clip integral with the spacer and removably securable to the first medical device in a first position to secure the spacer in the unlock position, and removably securable to the first medical device in a second position to secure the spacer in the lock position.

A system to facilitate sealing a puncture of a vessel includes an implant having first and second expandable sections, and a delivery device that includes an inner tube and a circumscribing outer tube. The outer tube defines a first lumen configured to retain the implant, and a second lumen configured to channel fluid from the vessel through a distal opening proximal to the implant. A pusher circumscribed at least partially by the outer tube is configured to compress the implant to selectively expand the first and second expandable sections. The outer tube is selectively retractable relative to the inner tube such that the first expandable section remains substantially within the first lumen and the second expandable section is positioned outside of the first lumen. The outer tube is further selectively retractable relative to the inner tube such that the first expandable section is positioned outside of the first lumen.

A device for treating a left atrial appendage, including an implant having a contact member configured to engage an inside tissue surface of the left atrial appendage and configured to rotate in at least a first direction from a first position to at least a second position so as to twist the left atrial appendage when the contact member is engaged with an inside tissue surface of the left atrial appendage. Some embodiments can also include a securing element configured to move between a first position in which the securing element is decoupled from the contact member and a second position in which the securing element is coupled with the contact member.

Tissue plugs for occlusion of hollow anatomical structures and methods for their use are provided.

A mechanical locking assembly for an endovascular device, comprising a shaft comprising a main body a shaft comprising a main body and enlarged end, an inner channel component comprising a full collar formed on proximal end of the inner channel component, and an outer cage component comprising a partial collar formed on the outer cage component wherein the full collar of the inner channel component fully surrounds the outer cage component and the partial collar of the outer cage component at least partially surrounds the shaft.

There are shown and described embodiments of a closure device for closing holes in tissue, for example in the right atrial appendage. The closure device in particular embodiments includes first and second mesh closure members and a tether or stem connecting them. Embodiments of a delivery device for the closure device are also described.

The present embodiments provide an expandable mesh comprising a first coupling element, a second coupling element, and an intermediate portion disposed between the first coupling element and the second coupling element. Proximal retraction of the first coupling element relative to the second coupling element causes the intermediate portion to flare out to an enlarged width. In one embodiment, the first coupling element comprises a first tube and the second coupling element comprises a second tube.

A system to facilitate sealing a puncture of a vessel includes an implant having first and second expandable sections, and a delivery device that includes an inner tube and a circumscribing outer tube. The outer tube defines a first lumen configured to retain the implant, and a second lumen configured to channel fluid from the vessel through a distal opening proximal to the implant. A pusher circumscribed at least partially by the outer tube is configured to compress the implant to selectively expand the first and second expandable sections. The outer tube is selectively retractable relative to the inner tube such that the first expandable section remains substantially within the first lumen and the second expandable section is positioned outside of the first lumen. The outer tube is further selectively retractable relative to the inner tube such that the first expandable section is positioned outside of the first lumen.

A parachute-designed biodegradable occluder is provided. The parachute-designed biodegradable occluder is with a proximal end adjacent to a human body and a distal end far away from the human body. The parachute-designed biodegradable occluder includes an occluder stent internally provided with a baffle film, and a shapeable ring with changeable states. The occluder stent, the baffle film and the shapeable ring are respectively made of polymer materials being degradable in biological tissues. The occluder is made of a biodegradable polymer material, which is degradable or absorbable by human tissues after being implanted for a period of time to make a defect site composed of human tissues, realizing occlusion without foreign matter. The occlusion effect is particularly significant for children.