A system and method are presented for treating targeted tissue using cryoablation. An introducer canula and a cryoprobe are inserted the targeted tissue. The cryoprobe is cooled and an ice ball is formed. The cryoprobe is removed while the ice ball is still frozen, and an ultrasound catheter is inserted. Ultrasound generated within the ice ball is used to determine the distance from the ultrasound catheter to a perimeter of the ice ball. This is repeated at different angles to model a slice of the ice ball. The ultrasound catheter is moved radially, and the process is repeated to create a model of at least a portion of the ice ball. The ice ball model can be displayed on a registered set of images representing the targeted tissue to ensure that the tissue lies within the treatment zone of the ice ball.

A plasma scalpel head for spinal percutaneous puncture and an operation method of the plasma scalpel head for spinal percutaneous puncture are provided. The plasma scalpel head for spinal percutaneous puncture includes a needle core. The needle core includes a main ablation electrode and a needle core body. The main ablation electrode is arranged at an ablation end of the plasma scalpel head. The needle core body is externally provided with a first insulating layer. The first insulating layer is externally provided with a reflow electrode layer. A part of the first insulating layer that is not covered with the reflow electrode layer forms a main ablation electrode protection insulating ring. The reflow electrode layer is provided thereon with a second insulating layer, and a part of the reflow electrode layer that is not covered with the second insulating layer forms a reflow electrode.

A micro-sized cold atmospheric plasma accessory. The micro-sized cold atmospheric plasma accessory comprises a tube, an active electrode within said tube, and a nozzle at a distal end of said tube, said nozzle having an inner diameter less than 1 mm and a length less than 30 mm. A distal end inner diameter of said tube is greater than said inner diameter of said nozzle. The nozzle preferable is 15-25 mm in length. The nozzle may comprise stainless steel. The tube may have an inner diameter greater than 1 mm. The nozzle preferably has a distal end inner diameter less than 280 μm. The micro-sized cold atmospheric plasma accessory may further comprise a return electrode on an outside of said tube. The tube may comprise a quartz tube

An array of non-thermal plasma emitters is controlled to emit plasma based on application of an electric current at desired frequencies and a controlled power level. A power supply for an array controller includes a transformer that operates at the resonant frequency of the combined capacitance of the array and the cable connecting the array to the power supply. The power into the array is monitored by the controller and can be adjusted by the user. The controller monitors reflected power characteristics, such as harmonics of the alternating current, to determine initiation voltage of the plasma and/or resonant frequency plasma emitters. The array of non-thermal plasma emitters may be used in therapeutic, diagnostic, and/or medical sanitization applications, including where a non-thermal plasma treatment regimen is prescribed.

The present invention relates to a method for preventing or treating angiogenesis-related diseases using a liquid type plasma. More specifically, the present invention relates to a method for preparing a liquid type plasma for preventing or treating angiogenesis-related diseases, a pharmaceutical composition for preventing or treating angiogenesis-related diseases using a liquid type plasma prepared by the method, and a method for preventing or treating angiogenesis-related diseases using the liquid type plasma.

A system and method are presented for treating targeted tissue using cryoablation. An introducer canula and a cryoprobe are inserted the targeted tissue. The cryoprobe is cooled and an ice ball is formed. The cryoprobe is removed while the ice ball is still frozen, and an ultrasound catheter is inserted. Ultrasound generated within the ice ball is used to determine the distance from the ultrasound catheter to a perimeter of the ice ball. This is repeated at different angles to model a slice of the ice ball. The ultrasound catheter is moved radially, and the process is repeated to create a model of at least a portion of the ice ball. The ice ball model can be displayed on a registered set of images representing the targeted tissue to ensure that the tissue lies within the treatment zone of the ice ball.

The plasma sensor monitors parameters characterizing the condition of the plasma during the treatment phase and/or the change thereof in order to recognize a prefiguring or already occurred interruption of the plasma in this manner and to avoid this interruption and, in the ideal case, avoid this by already changing the voltage form previously. The mentioned mechanisms can be used by the control device (22) also during a pulse packet. The length of each pulse packet is adapted at each change of the voltage form according to their characteristics in order to guarantee a constant average power.

An electrosurgical wand is described, for treating a target tissue using electrosurgical energy, which has an elongate shaft with a handle end and a distal end. A first active electrode surface is disposed on the distal end of the shaft and a first digester electrode surface is recessed away from the first active electrode surface and electrically connected with the first active electrode surface. An aspiration aperture is also disposed adjacent the first active electrode surface and fluidly connected with an aspiration lumen, wherein the first digester electrode surface is disposed within the aspiration lumen.

A catheter system (100) used for treating a treatment site (106) within or adjacent to the heart valve (108) includes an energy source (124), an energy guide (122A), and a balloon assembly (104). The energy source (124) generates energy. The energy guide (122A) is configured to receive energy from the energy source (124). The balloon assembly (104) is positionable substantially adjacent to the treatment site (106). The balloon assembly (104) includes an outer balloon (104B) and an inner balloon (104A) that is positioned substantially within the outer balloon (104B). Each of the balloons (104A, 104B) has a balloon wall (130) that defines a balloon interior (146). Each of the balloons (104A, 104B) is configured to retain a balloon fluid (132) within the balloon interior (146). The balloon wall (130) of the inner balloon (104A) is positioned spaced apart from the balloon wall (130) of the outer balloon (104B) to define an interstitial space (146A) therebetween. A portion of the energy guide (122A) that receives the energy from the energy source (124) is positioned within the interstitial space (146A) between the balloons (104A, 104B) so that a plasma-induced bubble (134) is formed in the balloon fluid (132) within the interstitial space (146A).

A plasma treatment system includes a spout, a suction hole, a first electrode and a second electrode, an impedance acquisition unit, a liquid volume adjustment unit, and a first control unit. The first electrode and a second electrode are configured to generate plasma to treat a living tissue by the application of a voltage. The impedance acquisition unit acquires impedance between the first electrode and the second electrode. The liquid volume adjustment unit adjusts the supply volume or suction volume of the electrically conductive solution. The first control unit controls the liquid volume adjustment unit to increase or decrease the supply volume or suction volume of the electrically conductive solution based on the impedance.