Methods and systems are disclosed for removing a tattoo from a subject's skin by application of a cold plasma that is delivered via a liquid-gas mixture. The plasma can be delivered in the form of gas bubbles, in which at least a portion of gas is in the form of a plasma.

Devices and methods for image-based treatment with an instrument configured to apply variable amounts of treatment medium at different locations. Devices having an image caption device that is configured to capture the area to be treated. The device comprises an evaluation device that is configured to determine a treatment trace of the treatment medium relative to the area to be treated from data of the image capture device and to determine a spatially resolved dosage for the area to be treated based on the treatment trace. Devices having a representation device that is configured to display the treatment trace and/or the spatially resolved dosage optically for a user, relative to the tissue. Methods to optically indicate the locations of the area to be treated of the tissue surface that have already been treated and/or the dosage with which the respective treated locations have been treated.

A multi-functional electrosurgical plasma accessory having a handpiece and an extendable probe assembly. The extendable probe assembly has a shaft member, a tube, an electrode, a spacer and a collet. The shaft member and tube each may be formed of a plurality of structures assembled together, each may be of a single unitary design, or both together may be of a single unitary design. The shaft member has an interior channel, a distal end and a proximal end comprised of a neck portion at the distal end of the shaft member, a grip. The elongated portion of the shaft is movable within the spacer between a first position in which a portion of a distal end of the electrode extends out of the tube and a second portion in which the distal end of the electrode does not extend out of the tube.

An ultrapolar electrosurgery blade includes top and bottom thin elongated conductive members in vertical alignment and spaced apart from one another along their lengths, a non-conductive coating covering both the top and bottom thin elongated conductive members and the space located between them to create opposing non-conductive sides of the blade with conductive cutting and ends and conductive non-cutting ends exposed, and both return and active contact layers located on each of the opposing non-conductive sides of the blade. An ultrapolar electrosurgery blade assembly having argon beam capability further includes a non-conductive tube member having a slot positioned over the top of the ultrapolar electrosurgery blade and a conductive hollow tubular member contained within at least a portion of the non-conductive tube member.

A device for cold plasma endoscopy may include a cold plasma generating system, a catheter and electrically conductive means. The cold plasma generating system includes a gas source, an electrical source, a dielectric chamber, a first electrode surrounding the dielectric chamber and electrically connected to the electrical source. The catheter has a first lumen for carrying the cold plasma fluidly connected to the dielectric chamber at a proximal end and having an opening at a distal end for delivering the cold plasma. The electrically conductive means extend inside the first lumen. The electrical source is configured to apply a pulsed excitation signal to the first electrode. The device includes remotely actuated deployable confinement means for creating a confined space, wherein the opening of the first lumen is arranged in the confined space, the deployable confinement means allowing for confining the plasma substantially within the confined space.

A device having an optical element with a conductive coating. The device may include an optical element, a conductive material and at least one connector. The conductive material is disposed on at least a portion of the optical element. The optical element, for example, may be an object lens of an endoscope or an optical coupler. The connectors (acting as terminal(s)) are capable of providing energy (such as electrical energy) to the conductive material. In one aspect, the conductive material is an optically transparent material. Advantageously, the device may allow visualization of an object—such as body tissue or other matter—concurrent with the application of energy to the object via the conductive coating. This allows the user to observe the alteration of tissue and other matter in real time as the energy is delivered.

A treatment device for a body surface to be treated using a dielectric barrier plasma, including a high-voltage generator connected to a headpiece having a conductive element at least partially shielded by a dielectric wall that forms at least one part of an end wall facing the surface to be treated.

System and method for selectively applying electrical energy to structures within or on the surface of a patient's body and controlling the flow of an electrically conductive fluid from the application site to provide or maintain a desired operating condition of the electrosurgical device. An electrosurgical probe is in communication with a fluid transport apparatus through a fluid transport lumen having an opening at an end proximate the application site and disposed proximate the electrosurgical probe. A controller in communication with the fluid transport apparatus provides control signals to the fluid transport apparatus in response to at least one operating parameter associated with the system. Based on the received control signals, the fluid transport apparatus adjusts a flow rate of the electrically conductive fluid at the application site through the fluid transport lumen in response to at least one operating parameter associated with the system.

A method and system of sensitization of cancerous cells in a volume is disclosed. A plasma tube including a pair of electrodes coupled to a power supply is provided. The plasma tube generates a plasma jet between the electrodes. A controller is coupled to a power supply to control a discharge voltage to the electrodes to generate the plasma jet and direct an electro-magnetic field at the volume having cancerous cells and normal cells for a sufficient time to sensitize the cancer cells. A treatment device applies a treatment such as TMZ to the sensitized cancer cells after the cancer cells are sensitized by the electro-magnetic field.

An electrosurgical wand is disclosed. The electrosurgical wand includes a handle that defines a proximal end of the electrosurgical wand. The electrosurgical wand includes an elongate shaft coupled to the handle; the elongate shaft defines a suction lumen therein. The electrosurgical wand also includes an electrically insulative spacer (404) coupled to the distal end of the elongate shaft, whereby the spacer defines a suction channel (412) fluidly coupled to the suction lumen. The electrosurgical wand includes a first means for blocking defined by the spacer, an active electrode (402) coupled on the distal end of the spacer and a second means for blocking associated with the active electrode and in operational relationship to the first means for blocking. In the electrosurgical wand, the first means for blocking includes an annular trough (416) that fully encircles the suction channel of the spacer and the second means for blocking includes an annular wall (414).