The invention generally relates to systems and methods for therapeutically modulating nerves in or associated with a nasal region of a patient for the treatment of a rhinosinusitis condition.

Pulmonary vein isolation catheters and associated devices, systems, and methods are disclosed herein. In some embodiments, a pulmonary vein isolation catheter includes a tip section having an expandable portion and a deployment member. The expandable portion includes a plurality of mesh electrode panels that are electrically insulated from one another. The expandable portion is mechanically coupled to (i) the deployment member at a distalmost portion of the tip section and (ii) a distal end portion of a catheter shaft. The expandable portion is expandable and compressible via proximal and distal movement, respectively, of the deployment member. In some embodiments, the expandable portion in a deployed state is pear- or onion-shaped and includes a nose portion and/or an active body portion. The nose portion can be insulated and/or configured to fit within a pulmonary vein and position the active body portion against tissue about the ostium of the pulmonary vein.

An apparatus comprises a first jaw, a second jaw, a first handle, and a second handle. The second jaw is pivotally coupled with the first jaw. The first jaw and the second jaw are configured to grasp tissue. The jaws provide offset electrode surfaces that are operable to deliver bipolar RF energy to tissue grasped between the jaws. The apparatus is further operable to sever tissue. A lockout feature selectively prevents tissue severing, based on an energization state of the jaws.

A device for applying radiofrequency energy for sphincter treatment comprising a flexible outer tube, an expandable basket having a plurality of arms movable from a collapsed position to an expanded position, and a plurality of electrodes movable with respect to the arms from a retracted position to an extended position. An advancer is slidably disposed within the outer tube to move the plurality of electrodes to the extended position. An actuator moves the advancer from a first position to a second position to advance the plurality of electrodes. An aspiration tube extends within the outer tube. An assembly includes an aspiration disabler having a first position to enable aspiration from a distal portion of the aspiration tube to a proximal portion and a second position to disable aspiration.

A method and system for monitoring a microwave tissue ablation process, particularly the determination of an ablation size estimate during microwave ablation of such tissue. The method includes applying a correction value to the determined temperature value, so as to provide a corrected temperature value

A method and system for monitoring tissue temperature during microwave ablation of such tissue is disclosed. The method includes applying a predetermined correction value to a temperature measurement to provide a corrected temperature value.

A method includes, using a probe, applying irreversible electroporation (IRE) pulses to tissue over a time period to form a lesion in the tissue. A contact force applied to the tissue by the probe is measured over the time period. An IRE index is calculated based on the measured contact force and on a power level of the IRE pulses. Application of the IRE pulses to the tissue is ceased in response to the calculated IRE index reaching a prespecified target IRE index value.

A method of treating a patient with a therapeutic laser pulse includes applying a cooling mechanism to a first skin area, cooling a target skin area within the first the skin area from a first surface temperature to a second temperature through application of the cooling mechanism prior to application of the therapeutic laser pulse, initiating application of the therapeutic laser pulse at a first timepoint, while continuing to apply the cooling mechanism, determining a surface temperature of the target skin area a plurality of times during application of the therapeutic laser pulse at a refresh rate of 25 Hz to 400 Hz, and terminating the application of the therapeutic laser pulse at a second timepoint, based on the surface temperature determinations. Each of the plurality of surface temperature determinations occurs during a single therapeutic laser pulse duration from the first time point to the second timepoint.

Pursuant to embodiments of the present invention, a method of performing electronically controlled electrotherapy may include modifying or killing target cells and simultaneously modifying a secondary outcome by delivering electrical pulses and dynamically adjusting an energy delivery profile of the electrical pulses in response to a measurement. The secondary outcome may be a physical outcome, a biological outcome, and/or a systemic outcome.

Disclosed are a method and apparatus for safety control of radio frequency operation, and a radio frequency host. The method includes: when connecting ends of a plurality of radio frequency circuits connect an operated object to a radio frequency host, acquiring detection values of the plurality of radio frequency circuits; determining whether change amounts of the detection values reach a preset value range; when a number of target radio frequency circuits reaching the preset value range is not less than a preset number, selecting the preset number of target radio frequency circuits from the target radio frequency circuits according to a preset selection rule as radio frequency input circuits, and inputting radio frequency energy into the radio frequency input circuits; when the number of target radio frequency circuits reaching the preset value range is less than the preset number, not inputting radio frequency energy into any radio frequency circuit.