Systems, devices, and methods for identifying a target in a body using a spectroscopic feedback from the target are disclosed. An exemplary surgical feedback control system comprises a feedback analyzer configured to receive a reflected signal from a target in response to electromagnetic radiation directed at a target, and a controller in operative communication with the feedback analyzer. The controller can generate a control signal to a surgical system to perform a predetermined operation based upon the received reflected signal, including determining a composition of the target, or programming a laser setting to direct laser energy to the target.

The invention provides a therapeutic system comprising: a console, wherein the console comprises a controller and an energy generator; a therapeutic device comprising: an operational head configured for transmitting the energy output from to a biological tissue; and a memory device comprising control instructions, wherein said control instructions comprise instructions for controlling the console; a reversible memory operable linkage linking the memory device to the controller; and a reversible connector configured for operably linking the energy generator to the operational head. Optionally, the energy generator is a generator of ablation energy or heat energy (e.g. RF generator) and the control instructions comprise instructions for controlling the output of the energy generator. Optionally, the control instructions comprise one or more parameters of energy output or an algorithm configured for controlling the energy output. Optionally, the system further comprises one or more secondary therapeutic devices and the control instructions comprise instructions for controlling the one or more secondary therapeutic devices. Optionally, the system further comprises one or more sensors configured for sensing parameters of energy output or biological or environmental effects of the energy output and the control instructions comprise instructions for controlling the energy output and/or secondary therapeutic devices based on the parameters of energy output or biological or environmental effects. In some embodiments, one advantage provided by the present invention is the use of a single console with a plurality of interchangeable reversibly connected therapeutic devices.

A process that provides protective therapy for biological tissues or fluids includes applying a pulsed energy source to a target tissue or a target fluid having a chronic progressive disease or a risk of having a chronic progressive disease to therapeutically or prophylactically treat the target tissue or target fluid. The pulsed energy source has energy parameters selected so as to raise the target tissue or bodily target fluid temperature up to a predetermined temperature for a short period of time to achieve a therapeutic or prophylactic effect, while the average temperature rise of the target tissue or target fluid over a longer period of time is maintained at or below a predetermined level so as not to permanently damage the target tissue or target fluid.

Described here are methods and systems for the manipulation of ovarian tissues. The methods and systems may be used in the treatment of polycystic ovary syndrome (PCOS). The systems and methods may be useful in the treatment of infertility associated with PCOS.

The invention is a system for monitoring and controlling tissue ablation. The system includes a controller configured to selectively control energy emission from an electrode array of an ablation device based on ablation feedback received during an ablation procedure with the ablation device. The controller is configured to receive feedback data from one or more sensors during the ablation procedure, the feedback data comprising one or more measurements associated with at least one of operation of the electrode array of the ablation device and tissue adjacent to the electrode array. The controller is further configured to generate an ablation pattern for controlling energy emission from the electrode array of the ablation device in response to the received feedback data.

The apparatus includes a source of treatment radiation which is arranged to generate radiation at one of a plurality of radiation parameters (such as power levels), a control unit and a base unit. The control unit is arranged to removably dock with the base unit and includes a sensor which can sense one of a plurality of skin parameters, and an actuator for enabling a user to interface with the control unit. The control unit operates in a sensing mode, in which the control unit is undocked from the base unit to sense a parameter of skin to be treated (such as skin tone), and a control mode in which the control unit is docked to the docking unit and is arranged to select the power level of the radiation generated by the source.

A method of improving efficiency of an electrosurgical generator is presented, the method including controlling an output of an electrosurgical generator by converting a direct current (DC) to an alternating current (AC) using an inverter, and sensing a current and a voltage at an output of the inverter. The method further includes the steps of determining a power level based on the sensed voltage and the sensed current, determining an efficiency of the electrosurgical generator, and inserting a predetermined integer number of off cycles when the efficiency of the electrosurgical generator reaches a threshold power efficiency.

Ablation systems and methods of the present disclosure include a catheter including one or more image sensors. The one or more image sensors can facilitate, for example, positioning an ablation electrode at a treatment site of an anatomic structure and, additionally or alternatively, can facilitate controlling delivery of therapeutic energy to a treatment site of an anatomic structure.

Disclosed herein is a system for treating skin and/or nails with cold plasma. The system includes a discharge device, which includes a handle and an applicator mounted thereon, and control infrastructure, which includes a waveform generator. The applicator includes an elongated tube housing therein a cathode. The handle includes a flyback amplifier. The waveform generator is configured to induce the flyback amplifier to establish a voltage at the cathode. The voltage produced by the flyback amplifier is configured to allow generating a self-sustaining Townsend avalanche when a distal end of the tube is positioned sufficiently near a target site on a skin surface or a nail of a subject, such as to produce a cold plasma discharge directed at the target site and having an average power between about 0.1 μW and about 10 μW, so that the target site is not heated.

A method of ablating tissue with pulse field ablation energy includes generating a single pulse of energy between a first set of one or more conducting elements of a first polarity and a second set of one or more conducting elements of a second polarity, the single pulse of energy having a first pulse width and consecutively generating pulses of energy with opposite polarity to that of the single pulse of energy, the pulses having a collective pulse width equal to the first pulse width.