An electrode with a conduit includes: a tubular portion internally provided with a first conduit; a distal end portion provided at the distal end of the tubular portion; a second conduit that is provided inside the distal end portion, the second conduit being configured to communicate with the first conduit; an opening configured to communicate with the first conduit and the second conduit; a first hemostatic surface that has a flat surface extending from the distal end of the tubular portion in an extending direction of the second conduit, and serves as an electrode configured to cause a high-frequency current to flow through a biological tissue; and a second hemostatic surface that is connected to a distal end side of the first hemostatic surface and is provided at an end portion protruding toward a distal end side from the opening.

A manipulable portion of a catheter system advances out of a lumen of a catheter sheath at a distal end of a shaft, which is also within the lumen of the catheter sheath. The catheter system causes different advancement and retraction trajectories of a manipulable portion out of and into the lumen based at least upon different relative movements between the catheter sheath and the shaft. A projection and a corresponding receiver may be used to control relative positioning of the catheter sheath and the shaft, as well as to control positioning of the manipulable portion. The catheter system may control metering rates of a control element coupled to the manipulable portion during advancement and retraction of the manipulable portion. A control element of the catheter system has varying amounts of length outside a distal end of the catheter sheath during advancement and retraction of the manipulable portion.

The invention provides a therapeutic system comprising: a console, wherein the console comprises a controller and an energy generator; a therapeutic device comprising: an operational head configured for transmitting the energy output from to a biological tissue; and a memory device comprising control instructions, wherein said control instructions comprise instructions for controlling the console; a reversible memory operable linkage linking the memory device to the controller; and a reversible connector configured for operably linking the energy generator to the operational head.

Optionally, the energy generator is a generator of ablation energy or heat energy (e.g. RF generator) and the control instructions comprise instructions for controlling the output of the energy generator. Optionally, the control instructions comprise one or more parameters of energy output or an algorithm configured for controlling the energy output. Optionally, the system further comprises one or more secondary therapeutic devices and the control instructions comprise instructions for controlling the one or more secondary therapeutic devices. Optionally, the system further comprises one or more sensors configured for sensing parameters of energy output or biological or environmental effects of the energy output and the control instructions comprise instructions for controlling the energy output and/or secondary therapeutic devices based on the parameters of energy output or biological or environmental effects. In some embodiments, one advantage provided by the present invention is the use of a single console with a plurality of interchangeable reversibly connected therapeutic devices.

Devices, systems, and methods for treating pulmonary conditions, such as COPD and asthma, by denervating bronchial tissue using cryoablation. In one embodiment, a device for bronchial denervation comprises: an elongate body having a distal portion and a proximal portion opposite the distal portion; a treatment element at the distal portion of the elongate body; and a first recording electrode located distal to the treatment element and a second recording electrode located proximal to the treatment element, the first and second recording electrodes being configured to record electromyograms. In one embodiment, the device includes a fluid delivery element that is within the treatment element and that has a plurality of orifices aligned with an equatorial portion of the treatment element.

Systems, methods, and devices allow percutaneous mapping, orientation and/or ablation in bodily cavities or lumens. Such may include a structure that is percutaneously positionable in a cavity, such as an intra-cardiac cavity of a heart. Transducers carried by the structure are responsive to blood flow. For example, the transducers may sense temperature, temperature being related to convective cooling caused by blood flow. A controller discerns positional information or location, based on signals from the transducers. For example, blood flow may be greater and/or faster proximate a port in cardiac tissue than proximate tissue spaced from the port. Position information may allow precise ablation of selected tissue, for example tissue surround a port in the intra-cardiac cavity.

Apparatus, including a probe, containing a first lumen and a second lumen and having a distal end that contacts tissue of a living subject. A fluid supply delivers a cryogenic fluid through the first lumen to the distal end and receives cryogenic fluid returning via the second lumen. A temperature sensor is located at the distal end. A pressure sensor located at a proximal end of the first lumen measures a pressure of the cryogenic fluid. A processor controls a delivery rate of the cryogenic fluid from the fluid supply, so that, when a temperature measured by the temperature sensor is less than a preset guard temperature, the delivery sate is a preset low rate, and when the temperature measured by the temperature sensor is greater than or equal to the preset guard temperature, the delivery rate is set in response to a pressure measured by the pressure sensor.

A temperature management device for warming or cooling a person's body includes a device body, which has a fluid conduit for flowing fluid through the device body. The device body includes a contact surface to face and contact the person's body on which the device body is applied and is configured to conform to the person's body wherein the contact surface contacts the person's body and follows a surface topography of the person's body, and further provides a thermally conductive surface for transmitting thermal energy from the fluid flowing through the fluid conduit to the person's body.

Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO.sub.2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

A laser and a minimally invasive dental surgical procedure using the laser to stimulate periodontal tissue formation.

Cystic lesions can be treated by electroporation. For example, this document describes methods and devices for endoscopic ultrasound-guided ablation of cystic lesions using a needle for electroporation.