Ablation electrode assemblies include an inner core member and an outer shell surrounding the inner core member. The inner core member and the outer shell define a space or separation region therebetween. The inner core member is constructed from a thermally insulative material having a reduced thermal conductivity. In an embodiment, the space is a sealed or evacuated region. In other embodiments, irrigation fluid flows within the space. The ablation electrode assembly further includes at least one thermal sensor in some embodiments. Methods for providing irrigation fluid during cardiac ablation of targeted tissue are disclosed that include calculating the energy delivered to irrigation fluid as it flows within the ablation electrode assembly through temperature measurement of the irrigation fluid. Pulsatile flow of irrigation fluid can be utilized in some embodiments of the disclosure.

Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO.sub.2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

Targeted ablation of parathyroidal tissue is provided through hyperthermia adjuvant therapy. An in situ localization of parathyroidal tissue is obtained. A temperature-sensitive adjuvant is instilled into the parathyroidal tissue. Hyperthermia is therapeutically induced within the parathyroidal tissue. Heat-inducing energy is targeted into the parathyroidal tissue, which selectively includes the temperature-sensitive adjuvant. Application of the heat-inducing energy to the parathyroidal tissue is continued over a therapeutic range. In a further embodiment, the targeted ablation of the parathyroidal tissue is provided through hypothermia adjuvant therapy with the targeted use of cold-inducing energy.

The invention provides a therapeutic system comprising: a console, wherein the console comprises a controller and an energy generator; a therapeutic device comprising: an operational head configured for transmitting the energy output from to a biological tissue; and a memory device comprising control instructions, wherein said control instructions comprise instructions for controlling the console; a reversible memory operable linkage linking the memory device to the controller; and a reversible connector configured for operably linking the energy generator to the operational head. Optionally, the energy generator is a generator of ablation energy or heat energy (e.g. RF generator) and the control instructions comprise instructions for controlling the output of the energy generator. Optionally, the control instructions comprise one or more parameters of energy output or an algorithm configured for controlling the energy output. Optionally, the system further comprises one or more secondary therapeutic devices and the control instructions comprise instructions for controlling the one or more secondary therapeutic devices. Optionally, the system further comprises one or more sensors configured for sensing parameters of energy output or biological or environmental effects of the energy output and the control instructions comprise instructions for controlling the energy output and/or secondary therapeutic devices based on the parameters of energy output or biological or environmental effects. In some embodiments, one advantage provided by the present invention is the use of a single console with a plurality of interchangeable reversibly connected therapeutic devices.

Methods, systems and devices for applying energy to tissue, and more particularly relates to a system for ablating or modifying structures in a body with systems and methods that generate a flow of vapor at a controlled flow rate for applying energy to the body structure.

Catheters and methods are provided for determining a fluid flow rate of fluid located near a tip assembly of the catheter and providing an indication of the fluid flow condition and/or controlling one or more functions of the catheter based on the determined fluid rate. A method includes receiving a signal from a sensor located on a tip assembly of a catheter, the signal being indicative of a fluid flow condition of fluid located near the tip assembly. A processing device determines the fluid flow condition using the signal. Based on the determined fluid flow rate, the processor causes a device to output an indication of the determined fluid flow condition.

A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s).

A cryoablation temperature control method, system and computer-readable storage medium. The method is used to control a temperature of the interior of a cryoablation balloon and includes: generating, based on an acquired real-time temperature value and a preset target temperature value of the interior of the balloon and/or a real-time gas flow rate value and a target gas flow rate value of a gas recovery passage in a gas outlet channel for the balloon, a first target liquid inlet pressure control signal for controlling a liquid supply flow rate of a high-pressure proportional valve in a liquid supply channel for the balloon; generating, based on an acquired real-time gas pressure value on, and a preset target gas pressure value for, a gas outlet side of the balloon, a first target gas outlet pressure control signal for controlling a gas outlet flow rate of a low-pressure proportional valve in the gas outlet channel for the balloon and for coordinating with the first target liquid inlet pressure control signal to perform control so that a pressure in the interior of the balloon is within a predefined safe pressure threshold value range and the temperature of the interior of the balloon is brought to and/or maintained at the target temperature value. This application allows accurate temperature control within a wide range and a short procedure time.

A catheter treatment apparatus comprises an elongate tubular member and an expandable support. The expandable support comprises a radioactive substance to treat cancerous tissue and is configured to expand from a narrow profile for insertion to a wide profile to engage and treat tissue remaining after resection. The expandable support can be sized to fit within a volume of removed tissue to place the radioactive substance in proximity to the capsule and remaining tissue, to spare the capsule and proximate nerves and vessels to treat tissue in proximity to the capsule. The elongate tubular member may comprise a channel such as a lumen to pass a bodily fluid such as urine when the expandable support engages the tissue to treat the patient for a plurality of days. The treatment apparatus can be used to resect and diagnose tissue concurrently. Based on the diagnosis, targeted segmental treatment may be given.

A handpiece for a surgical instrument having a valve position sensing circuit arranged to detect the position of a valve arranged to control the flow of fluid through the suction lumen of the instrument. The distal end of the handpiece is arranged to couple to a cutting accessory. The handpiece comprises: a housing; a suction lumen within the housing extending from the distal end of the handpiece to a proximal end of the handpiece; a valve arranged to control the flow of fluid through the suction lumen; and a valve position sensing circuit arranged to detect a position of the valve. The valve position sensing circuit can be used to alert a surgeon if the valve is closed when it would be preferable for it to be open. For example, if the motor is overheating, the in-joint temperature is too high, or the RF component is activated.