An ingestible capsule arranged, in use, to cross a human stomach for carrying out a phototherapeutic treatment arranged to combat an infection due to the presence of the bacterium Helicobacter pylori, the ingestible capsule comprising at least one primary light source arranged to emit an electromagnetic phototherapeutic wave having a wavelength λ.sub.1, at least one auxiliary light source arranged to emit an electromagnetic phototherapeutic wave having a wavelength λ.sub.2, a wrapper arranged to contain the or each primary light source and the or each auxiliary light source, the wrapper being at least partially transparent to the wavelengths λ.sub.1, and λ.sub.2, a control unit arranged to selectively activate the or each primary light source and/or the or each auxiliary light source.

A device and method of using the device to detect the presence and composition of clots and other target objects in a circulatory vessel of a living subject is described. In particular, devices and methods of detecting the presence and composition of clots and other target objects in a circulatory vessel of a living subject using in vivo photoacoustic flow cytometry techniques is described.

An ultrasonic surgical instrument and method of sealing a tissue includes measuring a first measured termination parameter with a controller and terminating an ultrasonic energy and an RF energy when the first measured termination parameter reaches a set one of a first smaller tissue predetermined termination parameter or a first larger tissue predetermined termination parameter to thereby inhibit transecting the tissue. The ultrasonic surgical instrument further includes an end effector having an ultrasonic blade, an RF electrode, and a controller. The controller operatively connects to the ultrasonic blade and the RF electrode and is configured to terminate the ultrasonic energy and the RF energy when the first measured termination parameter reaches the set one of the first smaller tissue predetermined termination parameter or the first larger tissue predetermined termination parameter to thereby inhibit transecting the tissue.

A surgical laser system includes a first laser source, a second laser source, a beam combiner and a laser probe. The first laser source is configured to output a first laser pulse train comprising first laser pulses. The second laser source is configured to output a second laser pulse train comprising second laser pulses. The beam combiner is configured to combine the first and second laser pulse trains and output a combined laser pulse train comprising the first and second laser pulses. The laser probe is optically coupled to an output of the beam combiner and is configured to discharge the combined laser pulse train.

A surgical laser system (100) includes a first laser source (140A), a second laser source (140B), a beam combiner (142) and a laser probe (108). The first laser source is configured to output a first laser pulse train (144, 104A) comprising first laser pulses (146). The second laser source is configured to output a second laser pulse train (148, 104B) comprising second laser pulses (150). The beam combiner is configured to combine the first and second laser pulse trains and output a combined laser pulse train (152, 104) comprising the first and second laser pulses. The laser probe is optically coupled to an output of the beam combiner and is configured to discharge the combined laser pulse train.

A device for providing tactile stimulation of a subject via a pulse of compressible fluid, typically for medical diagnostic and therapeutic applications. The device preferably includes a high pressure fluid source and a low pressure fluid source. A pressure valve selectively connects the pressure sources to an outlet conduit. The outlet conduit includes an applicator for directing pulses against the skin of a subject. The pulses may be applied via one applicator or a plurality of applicators, and may be applied in one pattern or several patterns at various application sites. A method of providing tactile stimulation is also disclosed.

Surgical instruments and system and methods for using surgical instruments are disclosed. A surgical instrument comprises an end effector comprising an ultrasonic blade and clamp arm, an electrode, an ultrasonic transducer, and a sensor coupled to a control circuit. The electrode receives electrosurgical energy from a generator and applies the electrosurgical energy to the end effector to weld tissue based on the generator generating a drive signal. The ultrasonic transducer ultrasonically oscillates the ultrasonic blade in response to the drive signal. The control circuit receives a signal from the sensor indicative of a surgical parameter, determines a weld time of a surgical operation based on the sensor signal, and varies one or more of a clamp arm pressure applied by the clamp arm and a power level of the electrosurgical energy to maintain one or more of a predefined heat flux or power applied to tissue loaded in the end effector.

Surgical instruments and system and methods for using surgical instruments are disclosed. A surgical instrument comprises an end effector comprising an ultrasonic blade and clamp arm, an ultrasonic transducer, and a control circuit. The ultrasonic transducer ultrasonically oscillates the ultrasonic blade in response to a drive signal from a generator. The end effector receives electrosurgical energy to weld tissue. The control circuit determines a resonant frequency measure indicative of a thermally induced change in resonant frequency and a electrical continuity measure; calculates a weld focal point based on the determined measures, controls closure of the clamp arm to vary a pressure applied by the clamp arm to provide a threshold control pressure to the tissue loaded into the end effector, and maintains a gap between the ultrasonic blade and clamp arm at a point proximal to the proximal end of the tissue. Pressure is varied based on corresponding weld focal point.

An ultrasonic surgical instrument and method of limiting an ultrasonic blade temperature includes adjusting at least one power parameter of the ultrasonic energy in response to reaching a predetermined frequency parameter change threshold in the ultrasonic blade limiting the temperature of the ultrasonic blade to an upper temperature limit. The ultrasonic surgical instrument further includes an end effector having an ultrasonic blade, a jaw, and a controller. The jaw is movably positioned relative to the ultrasonic blade and configured to move between an open position and a closed position. The controller operatively connects to the ultrasonic blade and is configured to measure an ultrasonic frequency of the ultrasonic blade. The controller has a memory including a plurality of predetermined data correlations that correlate changes in measured ultrasonic frequency of the ultrasonic blade to a blade temperature of the ultrasonic blade.

The present disclosure relates to devices, systems and methods for subdermal tissue tightening through soft tissue coagulation and for use in cosmetic surgery applications. The devices, systems and methods of the present disclosure may be used for a minimally invasive application of plasma energy to subcutaneous tissue for the purpose of tightening lax tissue. The present disclosure further provides several elasticity measurement devices, which are used to determine the elasticity of a tissue. The measurements obtained by the elasticity measurement devices are used to determine when a desired firmness or elasticity has been achieved during a tissue tightening procedure.