Electrochemical sensing device (S) for measuring the content of ions in biological fluid samples (D) comprising two membrane half cells, a salt bridge (3) connecting them, means for bringing a biological fluid sample (D) in contact with the measuring cell, wherein the first and second membranes (11, 21) of the half-cells are selective to the same ions, the first volume (13) and second volume (23) adjacent to the membranes are filled with known concentrations (C1, C2) of the ions to which the membranes (11, 21) are selective, these known concentrations being different such that a voltage can be measured between the first electrode (12) and the second electrode (22) that allows calibrating the sensing device (S) and then measuring the ion-content of the sample. The invention also refers to a method using such sensing devices. The sensing devices are useful especially in the area of so-called home monitoring.

Provided is a method for measuring a component of a biological sample with a biosensor provided with: a capillary for introducing the biological sample; an electrode part including a first electrode system that includes a first working electrode and a first counter electrode in the capillary; and a reagent part disposed so as to be in contact with the electrode part, the reagent part containing an enzyme and a mediator, and the method including a step of starting voltage application for a duration longer than 0 second and up to 0.7 second to the first electrode system within 0 second to 0.5 second after detection of the introduction of the biological sample to obtain a hematocrit value based on a current value obtained thereby.

A sensor device is for detecting metal. The sensor device may have a substrate, an electrode on the substrate, and a biopolymer-metal composite film on the electrode. The biopolymer-metal composite film may include a metal and a biopolymer. The sensor device may further have circuitry coupled to the electrode and configured to apply a sensing signal to the electrode.

A bioelectrochemical sensor utilizing a nanoporous gold electrode. The bioelectrochemical sensor is suitable for measuring redox in biologic media while having increased resistance to biofouling as compared to conventional electrodes such as planar gold electrodes, due to greater exposed surface area of the three-dimensional ligature structure defining the nanopores. The nanopores have a pore size of 5-100 nm, preferably with an average pore size of less than 50 nm, and more preferably with an average pore size of less than 20 nm.

The present invention provides a method and apparatus for creating test strips that may be identified based on differences in electrical conduction or resistance between contact point on the test strip. This is achieved by creating a base test strip with contact points that may be connected to other contact points by an electrical connection. These base test strips may be modified to create a difference in electrical conductivity between contact points, or a contact point may be eliminated. This modification can be used to distinguish different types of test strips based on electrical signature. Additionally, the base test strip may be created such that multiple modifications are possible to distinguish numerous characteristics of test strips.

Methods, systems, and devices are disclosed for the identification of chemical agents and determination of their level of exposure using electrochemical detection and advanced signal processing. In one aspect, a method includes collecting a sample from a surface containing a chemical agent to an electrode on a sensor such that the chemical agent transfers on the electrode, detecting an electrochemical signal of the chemical agent on the electrode to transduce chemical information associated with the chemical agent to an electrical signal, processing the electrical signal to obtain electrochemical spectral signature data to identify the chemical agent and generating a series of coefficients of the electrochemical spectral signature data to reduce the data, and classifying the chemical information based on the series of coefficients among preselected data sets to determine a level of exposure to the chemical agent.

Sensor elements are disclosed for the electrochemically analyzing a body fluid, as well as methods of producing and using the same. The sensor elements include an electrically conductive layer structure applied to a non-conductive carrier substrate, where the layer structure includes a continuous base layer of tantalum, niobium or an alloy thereof, and a metallic cover layer formed on the base layer that covers the base layer either over the entire surface or in some regions. The metallic cover layer includes a more noble metal when compared to the base layer.

A gas sampling bag for gas pH measurement includes a main sampling chamber and an electrochemical test strip accommodating chamber for accommodating an electrochemical test strip. The electrochemical test strip includes a strip body, a working electrode, a pH sensing layer, a reference electrode and a solid water absorption layer. The working electrode has a first part located in a detection area of the strip body. The pH sensing layer is formed on the first part. The reference electrode has a second part located in the detection area. The solid water absorbing layer is formed on the detection area and covers the pH sensing layer and the second part. The solid water absorbing layer is used for absorbing or adsorbing water in the gas sample to form an electrical connection between the first and second parts.

A gas sampling bag for gas pH measurement includes a main sampling chamber and an electrochemical test strip accommodating chamber for accommodating an electrochemical test strip. The electrochemical test strip includes a strip body, a working electrode, a pH sensing layer, a reference electrode and a solid water absorption layer. The working electrode has a first part located in a detection area of the strip body. The pH sensing layer is formed on the first part. The reference electrode has a second part located in the detection area. The solid water absorbing layer is formed on the detection area and covers the pH sensing layer and the second part. The solid water absorbing layer is used for absorbing or adsorbing water in the gas sample to form an electrical connection between the first and second parts.

An analyte sensor for determining at least one analyte and a method for producing an analyte sensor are disclosed. The analyte sensor has a substrate. A working electrode and a conductive layer are located on different sites on the substrate. A layer having silver and/or a silver compound partially covers the conductive layer. A protective layer covers (i) the layer having silver, and also covers (ii) a portion of the conductive layer. The disclosed analyte sensor significantly reduces noise during measurements. The method can be performed in an easier manner compared to producing prior art analyte sensors and allows considerably higher tolerances during production.