Embodiment of the present disclosure disclose a tomographic imaging system for reconstructing an image of an internal structure of an object. An incident wavefield is transmitted into the object occupying a background domain embedding the object. The incident wavefield is scattered into multiple scattered wavefield by the object. The incident and scattered wavefields are measured as a total wavefield. The total wavefield propagates through a computational domain and a residual domain in the background domain that are defined by cross-domain and residual measurement operators. The total wavefield is used for the image reconstruction. The image is reconstructed by solving an optimization problem corresponding to the computational domain. The optimization problem is solved iteratively to minimize a difference between the total wavefield and a wavefield synthesized using a measurement operator and a Green's function operator from the reconstructed image. The reconstructed image is outputted via an output interface.

A device for imaging defects in a structure includes N transmitters and P receivers to be distributed over at least one surface of the structure and a central unit controlling the transmitters and receivers to sequentially record Q≤N×P signals (S) obtained from electrical signals provided by the receivers of Q different transmitter/receiver pairs, after reception of mechanical waves transmitted by the transmitters of these Q pairs. It further stores Q first and Q second corresponding reference signals (S.sub.REF1, S.sub.REF2), representative of the structure without defects and differing by random noise. A central processing unit is programmed to: correlate each signal obtained with the corresponding first reference signal, in such a way as to construct an image of probabilities of defects; correlate each first reference signal with the corresponding second reference signal, in such a way as to construct a reference noisy image; and subtract the reference noisy image from the image of probabilities of defects.

According to one embodiment, a control method includes setting a transmission angle of an ultrasonic wave to a standard angle. The control method further includes transmitting an ultrasonic wave at the set transmission angle and detecting an intensity of a reflected wave from an object. The control method further includes calculating a tilt angle based on a gradient of the intensity. The tilt angle indicates a tilt of the object. The control method further includes resetting the transmission angle based on the tilt angle.

In a first aspect, the present description relates to a system for non-invasively characterizing a heterogeneous medium using ultrasound, comprising at least one first array (10) of transducers configured to generate a series of incident ultrasound waves in a region of said heterogeneous medium and record the ultrasound waves which are backscattered by said region as a function of time, as well as a computing unit (42) which is coupled to said at least one first array of transducers and configured to: record an experimental reflection matrix defined between an emission basis at the input and the basis of the transducers at the output; determine, from said experimental reflection matrix, at least one first wideband reflection matrix defined in a focused base at the input and output; determine a first distortion matrix defined between said focused basis and an observation basis, said first distortion matrix resulting, directly or after a change of basis, from the term-by-term matrix product of said first wideband reflection matrix defined between said focused basis and an aberration correction basis, with the phase-conjugated matrix of a reference reflection matrix defined for a model medium, between the same bases; determine, from said first distortion matrix, at least one mapping of a physical parameter of said heterogeneous medium.

Described here are systems and methods for phase velocity imaging using an imaging system, such as an ultrasound system, an optical imaging system (e.g., an optical coherence tomography system), or a magnetic resonance imaging system. In general, systems and methods for constructing phase velocity images (e.g., 2D images, 3D images) from propagating mechanical wave motion data are described. The systems and methods described in the present disclosure operate in the frequency domain and can be implemented using a single frequency or a band of selected frequencies. If there are multiple mechanical wave sources within the field-of-view, directional filtering may be performed to separate mechanical waves propagating in different directions. The reconstructions described below can be performed for each of these directionally filtered components.

According to one embodiment, a control method includes setting a transmission angle of an ultrasonic wave to a standard angle. The control method further includes transmitting an ultrasonic wave at the set transmission angle and detecting an intensity of a reflected wave from an object. The control method further includes calculating a tilt angle based on a gradient of the intensity. The tilt angle indicates a tilt of the object. The control method further includes resetting the transmission angle based on the tilt angle.

A method for performing tomography on a structure supporting modes of guided propagation of elastic waves, the method includes the steps of: acquiring a plurality of signals propagating through the structure by means of a plurality of pairs of non-collocated elastic-wave sensors; for each pair of sensors, i. selecting one mode of guided propagation, ii. converting the measured signal into wave field for the selected mode, iii. determining an anisotropic calibration coefficient on the basis of a wave-field propagation model evaluated depending on the anisotropic wavenumber and on the distance between the sensors of the pair, and on the basis of the wave field or of a reference wave field corresponding to a healthy state of the structure, calibrating the wave fields using the determined calibration coefficients, performing tomography on the structure on the basis of the calibrated wave fields.

The present disclosure enables apparatus and methods for tracking medications and/or product units via smart-packaging concepts. Embodiments include sensors that monitor the state of a blister-card package having an unpatterned lidding film by measuring the impedance of each dispensing region of the lidding film that defines a portion of a blister. In some embodiments, the impedance is measured via a plurality of contact points arranged on opposite sides of each dispensing region, where the contact points are resistively or capacitively coupled with the lidding film. In some embodiments, the impedance map of a measurement region on the blister card is derived via electrical impedance tomography or electrical resistance tomography, where the measurement region includes a plurality of dispensing regions.

Aspects of the disclosure described herein related to packaging an ultrasound-on-a-chip. In some embodiments, an apparatus includes an ultrasound-on-a-chip that has through-silicon vias (TSVs) and an interposer coupled to the ultrasound-on-a-chip and including vias, where the ultrasound-on-a-chip is coupled to the interposer such that the TSVs in the ultrasound-on-a-chip are electrically connected to the vias in the interposer. In some embodiments, an apparatus includes an ultrasound-on-a-chip having bond pads, an interposer that has bond pads and that is coupled to the ultrasound-on-a-chip, and wirebonds extending from the bond pads on the ultrasound-on-a-chip to the bond pads on the interposer.

The present invention relates to a portable probe for photoacoustic tomography, capable of performing line-by-line scanning or area-by-area scanning by using a small number of light inputs; and a real-time photoacoustic tomography device. The probe for photoacoustic tomography includes: a lens receiving light inputs from an optical fiber so as to make the same proceed as small diameter parallel light; a Powell lens receiving the small diameter parallel light and generating a line beam of a predetermined thickness, and allowing energy dispersed on a line to be uniform on the entire line; a lens making the line beam pass therethrough such that the line beam has a predetermined width and a reduced thickness so as to be line-focused at a target area; an acoustic reflection glass for separating, from a light path, an acoustic wave outputted from the target area; and an acoustic measurement unit for measuring acoustic strength.