Systems and methods for analysis of a whole blood sample from an individual to determine the platelet function and coagulation status of the individual in a substantially automated and efficient matter. Also provided here are systems, reagent kits, and methods for concurrent assessment of platelet function and coagulation as they interact during hemostasis.

A photoionization detector comprised of a gas discharge lamp that ionizes molecules of interest to create ionized molecules and electrons and a sensor having at least one opening for UV light to pass through and electrically conductive patterns on the top and bottom surfaces of the plate. A negative electrical potential pattern can be on one of the top or the bottom surface and can include an interior portion that is at least a first distance away from every edge of the at least one opening. An electron collecting electrode pattern can be on the other of the top or the bottom surface and can substantially fill an area surrounding the opening such that the negative electrical potential pattern and the electron collecting electrode pattern are offset relative to each other. The ionized molecules are collectable by a bias electrode and electrons are collectable by a collector electrode.

A photoionization detector comprised of a gas discharge lamp that ionizes molecules of interest to create ionized molecules and electrons and a sensor having at least one opening for UV light to pass through and electrically conductive patterns on the top and bottom surfaces of the plate. A negative electrical potential pattern can be on one of the top or the bottom surface and can include an interior portion that is at least a first distance away from every edge of the at least one opening. An electron collecting electrode pattern can be on the other of the top or the bottom surface and can substantially fill an area surrounding the opening such that the negative electrical potential pattern and the electron collecting electrode pattern are offset relative to each other. The ionized molecules are collectable by a bias electrode and electrons are collectable by a collector electrode.

A photoionization detector sensor comprised of plate, at least one opening in the plate for UV light to pass through, and at least one electrically conductive pattern on at least one of the top and bottom surfaces of the plate. The at least one electrically conductive pattern can include a negative electrical potential pattern comprised of a first material. Further, the negative electrical potential pattern can have a void in its center, and the void can surround the at least one opening. The plate can be comprised of a second material that is different than the first material. The negative electrical potential pattern can be located on at least one of the top or the bottom surfaces, and the at least one electrically conductive pattern can further include an electron collecting electrode pattern on the other of top or bottom surface.

A photoionization detector sensor comprised of plate, at least one opening in the plate for UV light to pass through, and at least one electrically conductive pattern on at least one of the top and bottom surfaces of the plate. The at least one electrically conductive pattern can include a negative electrical potential pattern comprised of a first material. Further, the negative electrical potential pattern can have a void in its center, and the void can surround the at least one opening. The plate can be comprised of a second material that is different than the first material. The negative electrical potential pattern can be located on at least one of the top or the bottom surfaces, and the at least one electrically conductive pattern can further include an electron collecting electrode pattern on the other of top or bottom surface.

A gas chromatograph for analyzing content of a gas sample includes a sample gas inlet configured to receive the gas sample and a carrier gas source which provides a carrier gas. A separation column is configured such that individual component gases in the sample gas separate as they move through the separation column. A first sample valve is coupled to the sample gas inlet, the carrier gas source and to a sample loop which is configured to contain a sample volume of the gas sample. The first sample valve injects the sample volume into the separation column and individual component gases in the sample gas separate as they move through the separation column. A detector detects a concentration of an individual component gas as a function of a sensitivity of the detector. A controller changes a response factor of the gas chromatograph by changing at least one of the sensitivity of the detector and the sample volume.

A gas chromatograph for analyzing content of a gas sample includes a sample gas inlet configured to receive the gas sample and a carrier gas source which provides a carrier gas. A separation column is configured such that individual component gases in the sample gas separate as they move through the separation column. A first sample valve is coupled to the sample gas inlet, the carrier gas source and to a sample loop which is configured to contain a sample volume of the gas sample. The first sample valve injects the sample volume into the separation column and individual component gases in the sample gas separate as they move through the separation column. A detector detects a concentration of an individual component gas as a function of a sensitivity of the detector. A controller changes a response factor of the gas chromatograph by changing at least one of the sensitivity of the detector and the sample volume.