The present disclosure relates to a semiconductor apparatus and a potential measuring apparatus capable of preventing deterioration in signal characteristics due to parasitic capacitance caused by providing a configuration for realizing an electrode plating process when an electrode and an amplifier are provided on the same substrate. When a power source supplies a potential necessary for plating processing and a breaker reads a signal from liquid, and an amplifier amplifies and outputs the signal, the power source required for the plating processing is blocked with respect to the electrode. This is applicable to the potential measuring apparatus.

A yarn has a first conductive yarn having conductivity, a first insulating section covering the first conductive yarn and formed of an insulating material having absorbency, and a second conductive yarn having conductivity and disposed on an outer circumferential side of the first insulating section.

The present disclosure is drawn to microfluidic cellular membrane modification devices. In one example, a microfluidic cellular membrane modification device can include a microfluidic channel including a pumping portion and an electric field portion. An electrode pair can be positioned about the electric field portion. A bidirectional pump can be in fluid communication with the microfluidic channel at the pumping portion to move fluid backward and forward through the electric field portion.

A medical analyzer and coagulation profiler performs various interrogations on specimens. A motor with reduction gearing moves and a video camera observes the samples, the cartridges or parts thereof. Changes in images are compared and recorded with a central processor that controls a display. Power supply, temperature controller, motor and gearing are mounted in a box which attaches to a smartphone. The smartphone provides the video camera, illumination and central processor that control the movement, temperature and display. The device makes testing simpler for small hospitals, clinics, ambulances, remote locations and individuals and controls a number of parallel or serial devices operating simultaneously or sequentially. A cartridge insertion actuates a circular motion to generate a blood profile based on changes. Change is analyzed with a video camera and processor such as in a smartphone and is plotted to show an amplitude and time. A smartphone provides a specific movement pattern.

Various cell analysis systems of the present teachings can measure the electrical and metabolic activity of single, living cells with subcellular addressability and simultaneous data acquisition for between about 10 cells to about 500,000 cells in a single analysis. Various sensor array devices of the present teachings can have sensor arrays with between 20 million to 660 million ChemFET sensors built into a massively paralleled array and can provide for simultaneous measurement of cells with data acquisition rates in the kilohertz (kHz) range. As various ChemFET sensor arrays of the present teachings can detect chemical analytes as well detect changes in cell membrane potential, various cell analysis systems of the present teachings also provide for the controlled chemical and electrical interrogation of cells.

A system and method for rapidly determining ambient temperature in a fluid-analyte meter. The meter includes a housing defining an interior space and an area for receiving a fluid sample. A processor and a first temperature sensor are disposed within the interior space of said the housing. A second temperature sensor is disposed on the housing. One or more processors are configured to determine a first temperature value from temperature data received from the first temperature sensor. The processor(s) are also configured to apply a variable current to a temperature-adjustment source such that the second temperature sensor is adjusted to a predetermined steady-state temperature value different from the first temperature value. The processor(s) are further configured to determine an ambient temperature of an exterior space of the housing based on the applied variable current, pre-determined steady-state temperature, and received first temperature values.

A particle occurrence sensing circuit for microfluidic particle sensing includes a set of particle event indicators, each of which includes: a Coulter counter having a sensing electrode exposable to a fluid within a microfluidic channel and configured for providing a particle sensing signal; an input stage configured for providing an extracted particle sensing signal; and a particle event detector configured for providing a set of particle event occurrence signals. Each of the set of particle event occurrence signals indicates a sensed occurrence of a particle greater than or equal to a given reference particle size during fluid flow through the microfluidic channel to which the sensing electrode is exposed. The particle event detector includes a successive approximation (SA) analog-to-digital converter (ADC) configured for generating a plurality of reference particle size threshold values and successively comparing the extracted particle sensing signal amplitude with reference particle size threshold values.

A hand-held test meter includes an electrically and thermally insulating case (“ETIC”) with an outwardly facing surface, a test meter electrical component (“TMEC”) with a thermal contact portion disposed within the electrically-insulating case, and at least one thermal channel. The thermal channel includes a proximal contact portion with a proximal contact surface, a distal contact portion with a distal surface, and a channel portion connecting the proximal contact portion and the distal contact portion. The thermal channel is integrated with the ETIC such that the thermal channel extends through the ETIC from the outwardly facing surface and to the thermal contact portion of the TMEC. The extension is such that the proximal contact surface of the thermal channel is outside of the ETIC and the distal surface of the thermal channel is in contact with the thermal contact portion of the TMEC. The thermal channel is thermally conductive and electrically-insulating.

A nonenzymatic biosensor based on a metal-modified porous boron-doped diamond electrode, and a method for preparing the same and use thereof are provided. A working electrode of the nonenzymatic biosensor is a metal-modified porous boron-doped diamond electrode including a silicon wafer substrate and an electrode working layer arranged on a surface thereof, the electrode working layer is a porous boron-doped diamond layer modified with metal nanoparticles, and a pore surface of the porous boron-doped diamond layer contains an sp.sup.2 phase. In the present invention, by combining chemical vapor deposition and magnetron sputtering and by means of a tubular atmosphere annealing furnace and an electrochemical workstation, the preparation of a multi-metal-modified porous boron-doped diamond composite electrode is realized. The electrode has the characteristics of high sensitivity, stability, and resolution, and can be widely used in the fields of the construction of electrochemical biosensors, the detection of heavy metals, etc.

A medical device includes a housing that has a front face and a side face. The housing defines a window cavity on the front face and a button cavity in the side face. A display is disposed in the housing. The display is aligned in the housing for viewing through the window cavity. A window covers the display in the window cavity, and the display is at least partially visible through the window. The window extends along the front face to the button cavity in the side face. A button element is received in the button cavity. The button element and the window are separate components. The button element has opposing end edges that align with the end edges of the window where the button element and window meet to provide an impression that the window and the button element are integral with one another.