Provided herein is a portable test device, mass manufacture method and method of use for identification of at least one target drug of abuse. The portable detection kit can include a catalytic reagent, a solid support carrier, and an absorbent material. The colorimetric reagent and the catalytic reagent can be are affixed to the solid support carrier to form a reaction zone thereon. The colorimetric reagent and the catalytic reagent are configured to undergo chemical reaction with at least one target drug of abuse to produce a visible color change. The at least one target drug of abuse is selected from the group consisting of nicotine, cannabinoids, amphetamines, opioids, or cocaine. A target drug of abuse can be on vaping device surfaces and/or within vaping liquid formulations.

In a container including two accommodation parts each accommodating liquid, mixing of the liquids in a case of moving magnetic particles in the liquid accommodated in one accommodation part to the other accommodation part is suppressed. Provided is a container includes a first accommodation part which accommodates a first liquid containing magnetic particles, a second accommodation part which accommodates separated magnetic particles separated from the first liquid, and a second liquid, and a flow passage which allows the first accommodation part and the second accommodation part to communicate with each other, and through which the separated magnetic particles pass, in which the flow passage has a first staircase part including two or more steps from an inner bottom surface of the first accommodation part on a first accommodation part side.

Disclosed is method of improving flow of a liquid sample in an assay device, as well as a method of performing an assay on a liquid sample for the detection of one or more analytes of interest. The methods use the addition of a reagent, such as a wash reagent, to wet the fluid flow path of a sample prior to sample addition, thereby improving flow of the sample through the fluid flow path that has been wetted as opposed to flow of the sample through the fluid flow path that has not been wetted. The reagent wets the fluid flow path between the sample addition zone and the wicking zone.

A portable detection kit for identifying the presence of narcotic compounds (NCs) includes at least one chemical dye, a catalytic reagent, at least one solvent, and a least one surfactant. The at least one dry chemical dye is configured to undergo physic-chemical interaction with at least one predetermined NC to produce a color visible change. The at least one predetermined NC is selected from the group consisting of fentanyl analogues (FAs) and narcotics containing nitrogen heterocyclic moiety.

A testing device is disclosed in the present invention and includes a test strip, where the test strip includes a non-absorbent support sheet on which at least two or more testing areas are arranged, and liquid communication cannot be made between the testing areas, and the testing areas include an absorbent material thereon, and the absorbent material includes a reaction reagent that can detect an analyte in a urine sample or test the property of the urine sample; and the absorbent material, where the absorbent material is located under the support sheet; and when a liquid sample is dripped to each of the two or more testing areas, the absorbent material absorbs the excess liquid sample, thus avoiding interference of other testing areas where the liquid sample is not dripped.

Provided are fluorescent nanoparticles and their conjugates and methods of using the same for in vivo and in vitro diagnostics and other applications. In some embodiments, provided are fluorescent nanoparticles with high solid-state absolute quantum yield. In some embodiments, provided are methods of manufacturing such nanoparticles. Nanoparticles may comprise monomers, such as styrene, and fluorophores, such as AlEgen Bright Green.

A lateral flow test kit includes a cassette and a swab. The cassette comprises a vial of liquid closed by seal; a test strip; a passage leading from the exterior of the cassette to the vial; and a conduit communicating between the vial and the test strip. The swab can be inserted along the passage to cause a tip of the swab to enter the vial and release liquid from the vial. The liquid flows past a head of the swab to extract a sample and deliver it through the conduit 34 to the test strip. The passage may comprise an obstruction, which requires the user to push the swab past it with a force sufficient to penetrate the seal. The obstruction may also prevent removal of the used swab from the cassette. A distal end of the passage may be curved to deflect the tip of the swab towards the seal at a more favourable angle.

An application-analysable bodily fluid testing equipment (100, 200, 300) is provided. The application-analysable bodily fluid testing equipment comprises at least one testing region (109, 209, 309) sensitive to an indicator of a bodily condition in bodily fluid from which image data is capturable and analysable by an associated application on a device. The bodily fluid testing equipment further comprises a handling indicator (107, 207, 307) indicating an area of the equipment for a user to hold during the application of a bodily fluid to the at least one testing region, and during capture of the image data for analysis of the bodily fluid applied to the at least one testing region using the application on the device.

Provided are fluorescent nanoparticles and their conjugates and methods of using the same for in vivo and in vitro diagnostics and other applications. In some embodiments, provided are fluorescent nanoparticles with high solid-state absolute quantum yield. In some embodiments, provided are methods of manufacturing such nanoparticles. Nanoparticles may comprise monomers, such as styrene, and fluorophores, such as AIEgen Bright Green.

A test strip assembly for dipping in a bodily fluid sample to analyze the presence or absence of one or more analytes is provided. The test strip assembly includes a basal layer, a porous membrane positioned over the basal layer to allow bodily fluid to flow in a lateral direction within the porous membrane, and a plurality of detection labels placed on the porous membrane. The detection labels receive bodily fluid flowing laterally through the porous membrane and redirect the flow in a vertical direction within the detection labels to enable interaction with reagents for analyte detection. A device including one or more such test strip assemblies is also provided.