A mobile device based multi-analyte testing analyzer for use in medical diagnostic monitoring and screening, and a method of manufacturing the same are disclosed. A reflectance based, colorimetric test strip reader for use with a mobile device having a jack plug receiving socket, said test strip reader adapted for removably receiving a test strip having a test strip longitudinal axis, comprising a housing; a jack plug operably coupled to and extending from said housing and adapted for operable coupling with said jack plug receiving socket; a test strip adapter including structure defining a test strip receiving channel; a light source oriented within said housing for directing light toward said test strip receiving channel to illuminate a test strip arranged within said test strip adapter; and a light sensor oriented within said housing to sense light reflected from a test strip carried by said test strip receiving channel.

Methods and devices for detecting a low concentration analyte in a sample are provided herein. The methods include flowing a sample through a porous membrane coated with a capture matrix to capture the low concentration analyte. The methods also can include detecting the captured analyte, such as by performing in-situ amplification of the analyte.

The present invention provides methods of determining cell sensitivity to a therapeutic agent.

A method for determining an indicator of a bodily condition in an image of a bodily fluid testing equipment captured by an electronic device is provided. The method comprises acquiring image data of a bodily fluid testing equipment (100, 200), determining at least one edge (539) of a first bodily fluid testing region (109, 209), determining a location of the first bodily fluid testing region, sampling colour data of a sub-region (541) of the first bodily fluid testing region, determining, based upon the sampled colour data, whether an indicator of a bodily condition has interacted with the first bodily testing region and providing an output, wherein the output is based upon whether the indicator of the bodily condition has interacted with the first bodily fluid testing region.

A colorimetric sensor for detecting bacteria and/or includes one or more layers having a photonic crystal structure a functional layer comprising a nanomaterial capable of generating bacteria- and/or viruses-bioresponsive surface plasmon overlapping the one or more layers having the photonic crystal structure. The bacteria- and/or viruses-bioresponsive nanomaterial of the functional layer is doped with proteinic substances or antibodies acting as virus receptors, or the colorimetric sensor comprises a receptor layer comprising proteinic substances or antibodies acting as virus receptors. The functional layer and receptor layer overlap each other. Alternatively, or in addition to, the colorimetric sensor comprises a plasmonic nanostructured layer comprising nanostructures such to generate plasmonic colors, overlapping the one or more layers having the photonic crystal structure.

The disclosed technology includes a planar device for performing multiple biochemical assays at the same time, or nearly the same time. Each assay may include a biosample including a biochemical, enzyme, DNA, and/or any other biochemical or biological sample. Each assay may include one or more tags including dyes and/or other chemicals/reagents whose optical characteristics change based on chemical characteristics of the biological sample being tested. Each assay may be optically pumped to cause one or more of luminescence, phosphorescence, or fluorescence of the assay that may be detected by one or more optical detectors. For example, an assay may include two tags and a biosample. Each tag may be pumped by different wavelengths of light and may produce different wavelengths of light that is filtered and detected by one or more detectors. The pump wavelengths may be different from one another and different from the produced wavelengths.

A chromatographic strip support tool (except one that includes a chromatographic strip) is provided. The chromatographic strip support tool includes a support surface that is continuous and on which the chromatographic strip can be placed, a projected portion formed on the support surface and having a first abutting portion that can abut against an extremity of the chromatographic strip placed on the support surface, the extremity being present at one end side of the chromatographic strip, and a display section formed on the support surface and displaying a detection item corresponding to a predetermined location of the chromatographic strip with the chromatographic strip being placed on the support surface in a manner that the extremity of the chromatographic strip abuts against the first abutting portion.

A lateral flow test kit includes a cassette and a swab. The cassette comprises a vial of liquid closed by seal; a test strip; a passage leading from the exterior of the cassette to the vial; and a conduit communicating between the vial and the test strip. The swab can be inserted along the passage to cause a tip of the swab to enter the vial and release liquid from the vial. The liquid flows past a head of the swab to extract a sample and deliver it through the conduit 34 to the test strip. The passage may comprise an obstruction, which requires the user to push the swab past it with a force sufficient to penetrate the seal. The obstruction may also prevent removal of the used swab from the cassette. A distal end of the passage may be curved to deflect the tip of the swab towards the seal at a more favourable angle.

The present disclosure provides compositions and methods for detecting the presence of neutralizing antibodies in a sample. Unlike conventional assays, the methods provided herein do not require the use of live virus or virus pseudoparticles to identify neutralizing antibodies.

Color-based (colorimetric) breast milk analyses using test strips (paper-based assays) read with the smartphone camera to quantify the concentration in accordance with embodiments of the invention are disclosed. In one embodiment, a color-based strip for testing breast milk is provided, the strip including: a first portion including a protein reagent pad where exposing the protein reagent pad to breast milk results in a first enzymatic reaction for measurement of total protein concentration in the breast milk, a second portion including a fat regent pad where exposing the fat reagent pad to breast milk results in a second enzymatic reaction for measurement of fat concentration in the breast milk, and a third portion comprising a lactose reagent pad where exposing the lactose reagent pad to breast milk results in a third enzymatic reaction for measurement of lactose concentration in the breast milk.