Patent classifications
G01N33/521
Composition comprising up-converting phosphors for detecting an analyte
The present invention relates to a detector matrix for detecting at least one analyte in a sample, preferably a sample of a body fluid, comprising at least one enzyme active in the presence of said at least one analyte and at least one indicator reagent changing at least one optical property dependent on the activity of said enzyme, wherein said detector matrix further comprises up-converting phosphor particles, preferably UV-emitting up-converting phosphor particles. The invention further relates to a test element and a test device for detecting at least one analyte in a sample comprising the detector matrix of the invention, as well as to a method for the manufacture of a detector matrix, a method for the manufacture of a test element, and to a method for detecting an analyte in a sample, comprising contacting a detector matrix according to the invention with a sample suspected to comprise said analyte.
ON DEMAND, PORTABLE, CELL-FREE MOLECULAR SENSING PLATFORM
Disclosed are methods, devices, kits, components, and compositions for detecting a target molecule in a test sample using a cell-free protein synthesis (CFPS) reaction. The methods, devices, kits, components, and compositions may be utilized for detecting target molecules which may include small molecules and/or metabolites of small molecules. The components and compositions used in the disclosed methods, devices, and kits may be dried or lyophilized and may be present or immobilized on a paper substrate, for example, as a paper test article.
Specimen tube
A specimen tube comprises a tubular body having a first end that is open, a second end that is closed and at least one side extending axially between the first end and the second end. The side and the closed end define an interior of the tube. In sonic implementations, the specimen tube comprises a plurality of foot members protruding from the second end of the tube, wherein at least a first foot member and a second foot member have different shapes from each other. In some implementations, at least one internal wall positioned within the interior of the tube defines a sample carrier holding space between at least one surface of the internal wall and an adjacent surface of the side of the tube, the sample carrier holding space being sized to store a swab inserted from the open end of the tube.
Method of improving liquid sample flow in assay device
Disclosed is method of improving flow of a liquid sample in an assay device, as well as a method of performing an assay on a liquid sample for the detection of one or more analytes of interest. The methods use the addition of a reagent, such as a wash reagent, to wet the fluid flow path of a sample prior to sample addition, thereby improving flow of the sample through the fluid flow path that has been wetted as opposed to flow of the sample through the fluid flow path that has not been wetted. The reagent wets the fluid flow path between the sample addition zone and the wicking zone.
URINAL SCREEN
The present invention is a urinal screen that includes a main body having an extended upper surface, a corresponding extended lower surface, and a marginal edge portion integral with an surrounding the upper surface and the lower surface; a plurality of spaced apart apertures formed to extent through the main body to provide fluid communication between the upper surface and the lower surface of the main body; and a two-sided spreading layer attached to the main body for accepting a urine sample on a upper side and passing the sample to a lower side, opposite and each side containing a reagent that can react with glucose in the urine sample, as it passes through the two-sided spreading layer, to cause a color change in the reagent.
IDENTIFICATION OF DEGRADATIVE SPECIES
A sensor (e.g., an optical sensor) that may be implanted within a living animal (e.g., a human) and may be used to measure an analyte (e.g., glucose or oxygen) in a medium (e.g., interstitial fluid, blood, or intraperitoneal fluid) within the animal. The sensor may include a sensor substrate, electrode or housing, an analyte indicator covering at least a portion of the sensor, and one or more probes that identify degradative species in an environment of the sensor.
ANTI-HYPUSINE ANTIBODIES AND USES THEREOF
The invention provides anti-hypusine antibodies and their use in detecting and isolating polypeptides containing hypusine and/or deoxyhypusine, as well as compositions and kits comprising the anti-hypusine antibodies.
System and Method for Detection of Target Substances
A system and method for detecting harmful substances within a consumable sample comprising: receiving a consumable sample at a first chamber of a test container; transforming the consumable sample into a homogenized sample upon processing of the consumable sample; delivering the homogenized sample to a second chamber of the test container, wherein the second chamber is configured to receive the homogenized sample comprises an outlet port; mixing the homogenized sample with a process reagent within the second chamber, thereby producing a dispersion; transmitting a volume of the dispersion to an analysis chamber, of the test container, configured to position a detection substrate proximal the port of the second chamber and comprising a detection window that enables detection of presence of the allergen; and detecting presence of the allergen within the consumable sample by way of an optical sensor configured to detect signals indicative of the allergen through the detection window.
METHOD OF CAPTURING AND STABILISING THIOLS
The present invention relates to a method of capturing and stabilising volatile thiol malodour generated on the human skin, comprising steps of: i) contacting the human skin with a substrate, ii) absorbing said thiol into the substrate, and iii) reacting said thiol with a thiol-capture agent. The invention also relates to a method of quantifying said thiol, a method of assessing the deodorizing performance of a cosmetic composition on the human skin.
POLY(DIACETYLENE) SENSOR ARRAYS FOR CHARACTERIZING AQUEOUS SOLUTIONS
The present invention relates to colorimetric polydiacetylene (PDA) sensor arrays for detection of analytes and levels thereof in aqueous solutions. In particular the present invention relates to methods of characterizing an aqueous solution for at least one analyte, comprising the steps of a) providing a sensor array comprising at least two different poly-diacetylenes, wherein said poly-diacetylenes are spatially separated and individually addressable, b) contacting said sensor array with a sample of said aqueous solution, c) measuring the colorimetric response of said poly-diacetylenes to the aqueous solution, wherein said poly-diacetylenes are polymerized from a composition comprising one or more diacetylene monomer(s) said poly-diacetylenes are capable of a colorimetric response upon contact with said analyte, and wherein the at least one analyte is selected from the group consisting of an organic molecule with a molecular weight below 2000 g/mol, salts thereof and an inorganic salt.