Technology is disclosed for a cat litter that can be used to diagnose feline medical conditions. A cat litter contains an additive, e.g., a chemical agent, such as a natural and/or synthetic agent, that changes in color when it comes in contact with cat urine or feces. Based on the color it can be determined whether the cat has a medical condition, such as particular illness. For example, if the litter turns yellow when it comes in contact with the urine, it can indicate that the cat is healthy. If the litter turns to a color other than yellow, e.g., green, it can indicate that the cat has some illness. The cat then be taken to a veterinary doctor for further diagnosis. The chemical agent aids in detection and diagnosis through interaction of materials that change colors to indicate reactions with specific chemicals, cells, molecules, DNA and/or materials. The technology can be implemented for medical diagnosis and detection—for humans and/or animals.

The invention is an analytical toilet and a method. The toilet, includes a bowl adapted to receive urine. A passage is provided for transferring a sample of the urine to a detection system. The detection system is configured to receive the sample and detect a virus. When the sample is brought into contact with the detection system, the detection system indicates the presence of a virus by generating a distinct signal. Preferably, the detection system makes use of a nucleic acid amplification test (NAAT), such as a quantitative PCR instrument. The method makes use of the analytical toilet and is designed to detect the presence or absence of targeted genetic material, preferably genetic material from a virus, such as SARS-CoV-2.

Described is a method to detect an analyte in an analytical toilet that includes the steps of receiving excreta in a bowl, transporting a measured sample of the excreta through a passage and bringing the sample into contact with a sensor. The sensor comprises a FET configured to interact with an analyte in the excreta. When the sample is brought into contact with the sensor, the sensor indicates the presence of the analyte by a distinct electric signal.

A biochip packaging structure includes a chip packaging layer, a redistribution layer, and a microfluidic channel. The chip packaging layer includes a resin layer including a biochip and a conductive pillar located on each of two sides of the biochip. The biochip includes a first surface flush with and exposed out of a side of the resin layer. A first end of the conductive pillar is flush with a side of the resin layer opposite the biochip. A second end of the conductive pillar is flush with the first surface of the biochip. The redistribution layer includes a metal winding electrically coupled to the biochip and the adjacent conductive pillar. The metal winding includes a first winding portion coupled to the biochip and a second winding portion coupled between the first winding portion and the conductive pillar. The second winding portion is parallel to the first surface.

A condom for detection of STDs, including an interior condom surface having a control band and a test band, and an exterior condom surface that also has a control band and test band. Each test band allows binding and subsequent detection of STD antigens. A separate developing antibody produces a color change if bound to the antigen/antibody conjugate. The developing antibody may be present on the condom or applied separately after use.

A reagent test paddle includes a contamination detection medium, a reference color bar, at least one chemical test medium, and a unique identifier. The contamination detection medium includes a reagent that changes color in the presence or when exposed to a hostile or inhospitable environment. Each chemical test medium includes a regent that is responsive to a respective analyte in a biological sample. The reference color bar includes reference color samples of different colors. The unique identifier, like a serial number, identifies the particular paddle and its chemical test medium so it can be uniquely and anonymously associated with a user. A method includes capturing and interpreting digital images of a biologically unexposed and subsequently exposed reagent test paddle at various delay times within an automatically calibrated environment; locating the paddle in a plurality of digital images, extracting the reference color bar and locating the contamination detection medium and chemical test medium in each digital image. Color changes of the chemical test medium and contamination medium are detected at various delay times after sample exposure. To determine validity of test results, the method further compares the detected colors of the contamination detection medium with predetermined colors expected for no contamination and contamination.

The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.

An unmanned vehicle operated autonomously or by remotely piloting incorporates an onboard camera which is affixed with clear tape coated with a chemical colorimetric sensor dye sensitive to chemical warfare agents. Chemical warfare agents are detected by visual review or autonomous measurement of sensor color changes while the unmanned vehicle travels through a region suspected of having chemical warfare agents present. In various implementations, the sensor output color changes may be visually monitored by a vehicle operator viewing the camera image from a remote location. In various embodiments, the detection of chemical warfare agents may be confirmed by processing the coated tape with a calibrated opto-electronic reader.

A reagent test paddle includes a contamination detection medium, a reference color bar, at least one chemical test medium, and a unique identifier. The contamination detection medium includes a reagent that changes color in the presence or when exposed to a hostile or inhospitable environment. Each chemical test medium includes a regent that is responsive to a respective analyte in a biological sample. The reference color bar includes reference color samples of different colors. The unique identifier, like a serial number, identifies the particular paddle and its chemical test medium so it can be uniquely and anonymously associated with a user. A method includes capturing and interpreting digital images of a biologically unexposed and subsequently exposed reagent test paddle at various delay times within an automatically calibrated environment; locating the paddle in a plurality of digital images, extracting the reference color bar and locating the contamination detection medium and chemical test medium in each digital image. Color changes of the chemical test medium and contamination medium are detected at various delay times after sample exposure. To determine validity of test results, the method further compares the detected colors of the contamination detection medium with predetermined colors expected for no contamination and contamination.

The invention provides device and method for detecting infection in a body fluid, in particular in wound exudates and urine, based on protease activity. The device is founded on a detector consisting of one layer, which is an absorbent layer impregnated with a solution formed by dissolving a pH sensitive dye, such as bromothymol blue, in a gelatin solution. The method uses the device in form of a test strip for quick detection of an infection by observing a change in the color of the detector.