A heart valve stent having a section with a heart valve implant and several proximally disposed tissue anchors, also comprising a plurality of anchoring threats, each with a proximate end fastened to the stent or valve and a distal end attached to tissue within a heart chamber to provide tension between the heart chamber tissue and the stent.

A method of making a valve structure includes a step of rotating a mandrel and an electrodeposition target attached to the mandrel about a rotational axis of the mandrel. The target includes an exterior surface having at least one conductive surface portion and at least one non-conductive surface portion. The method also includes a step of electrodepositing a polymer matrix of a biodegradable, biocompatible polymer composition onto the at least one conductive surface portion and the at least one non-conductive surface portion of the exterior surface of the rotating electrodeposition target to form the valve structure.

Embodiments of the present disclosure includes an endcap to be attached onto a corpectomy cage. The endcap may include a first surface configured to attach to a central core of the corpectomy cage. In some instances, the endcap may also include a second surface configured to engage with a vertebra at one end of the intervertebral cavity space. Additionally, a cavity may be formed within the endcap of the cavity floor to contain bone material that may be fused with the vertebra. The cavity may have an opening at least partially surrounded by the second surface.

Valve repair devices are disclosed herein. One valve repair device has a main shaft and a pair of paddles. The pair of paddles include a connection portion, an inner paddle portion, and an outer paddle portion. Each connection portion of the pair of paddles is connected to the main shaft. The pair of paddles are moveable between an open position and a closed position.

A medical arrangement is configured to introduce an object, such as an implant or medicament, from a distal end of the arrangement into an anatomical target position. The medical arrangement comprises a first and second introducer, both having distal and proximal ends. The first introducer is an outer introducer and the second introducer is configured to be operated inside and guided by the first introducer. In addition, at least a portion of the first introducer is configured to take a first curved shape, and at least a portion of the second introducer is configured to take a second curved shape so that the first and second curved shapes are concentric curved shapes so all curves are in the same hand direction and thereby form a helical loop structure.

Disclosed herein are gender-specific implantable mesh for inguinal hernia repair in a patient, comprising: a fabric layer comprising a side defining a surface area wherein the fabric layer is configured to enable tissue adhesion to said mesh; an anti-adhesive barrier comprising a shape configured to prevent direct contact between the fabric layer and both a spermatic cord and a genital nerve upon implantation, wherein the shape covers a part of the surface area on the side of the fabric layer, the part being less than 25%, and wherein the shape is oblique to a horizontally-oriented centerline and a vertically-oriented centerline; and a keyhole configured to fit the genital nerve and the spermatic cord of the patient therethrough without constriction, wherein the keyhole is oblique and inferior to a horizontally-oriented centerline and medial to a vertically-oriented centerline.

A placeholder for vertebrae or vertebral discs includes a tubular body, which along its jacket surface has a plurality of breakthroughs or openings for over-growth with adjacent tissue. The placeholder includes at least a second tubular body provided with a plurality of breakthroughs and openings at least partially inside the first tubular body. The first and second tubular bodies can have different cross-sectional shapes, can be are arranged inside one another by press fit or force fit or can be connected to each other via connecting pins and arranged side by side to one another in the first body.

Apparatus (20) is provided, including a bifurcation stent (50) comprising one or more electrodes (32), the stent (50) configured to be placed in a primary passage (52) and a secondary passage (54) of a blood vessel (30), and a control unit (34), configured to drive the electrodes (32) to apply a signal to a wall (36) of the blood vessel (30), and to configure the signal to increase nitric oxide (NO) secretion by the wall (36). Other embodiments are also described.

A vaginal device and method of preventing urinary incontinence is disclosed. The device includes a longitudinal portion having a geometrical centre line, a first end and a second end, the first end being the innermost of the vaginal device during use, at least one supporting portion protruding from the longitudinal portion at the first end, the at least one supporting portion being configured to support against the urethra, through the vaginal wall, at a site located adjacent the maximal urethral pressure point, and a reference member protruding from the longitudinal portion at the second end, wherein the reference member during use is fixated against the vaginal introitus, holding the vaginal device securely fixated inside of the vagina and ensuring the at least one supporting portion is arranged at the intended site. The device further includes a section of the longitudinal portion, arranged between the supporting portion and the reference member, that has a decreasing cross-section towards the reference member and/or has at least one notch, groove and/or slot in an outer surface along an axial direction of the section.

A drainage stent delivery system is disclosed. The drainage stent delivery system includes a catheter body, a stent member, and a coupling member. In some embodiments the coupling member can include keyed connectors having a non-round shape to facilitate a 1:1 rotation ration of the catheter body and the stent member. In another embodiment, the coupling member can include a telescoping connector having an inner tube and a release wire disposed through the inner tube. A distal portion of the release wire has an outer diameter greater than an inner diameter of the inner tube such that the telescoping connector can be displace by the release wire. In another embodiment, the stent member includes a proximal retention member having arms that are outwardly extendable.