A prosthetic implant has a self-expanding frame with an inflow end, an outflow end, and a plurality of struts interconnected at junctions. At least a portion of the plurality of struts have a reduced strut width at at least one junction configured to reduce or prevent infolding of the frame during recapture into a delivery cylinder of a delivery apparatus.

Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Deployment systems and methods for using the deployment systems described herein facilitate implanting a two-part prosthetic heart valve that is arranged in a nested configuration during the transcatheter delivery and deployment processes.

Heart valve replacement often involves complications associated with paravalvular leaks. Vascular plug and occlusive devices, as well as heart valves particularly beneficial in treating the phenomenon of paravalvular leaks are described to address this issue.

A surgical implant for repairing a defect. The implant has a first layer and a second layer. Each layer is flexible and planar. The first layer has an inner portion remote from a periphery, and an outer portion between the periphery and the inner portion. The second layer has an inner portion remote from a periphery, and an outer portion between the periphery and the inner portion. A bottom surface of the first layer near the inner portion thereof is connected to top surface of the second layer near the inner portion thereof so that the inner portion of the top layer is fixed relative to the inner portion of the second layer and the outer portion of the first layer is moveable relative to the outer portion of the second layer.

The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to medical devices for facilitating the flow of fluids and materials in a lumen and/or between adjacent body lumens; for example, a stent which maintains an open flow passage between body lumens. In one example, a stent may comprise first and second flanges and an elongate body therebetween. The elongate body may extend outwardly beyond the elongate body such that ends may be doubled back into the respective first and second flanges.

A hair implant suitable for subcutaneous implantation is provided having an anchor comprising an anchor body, and at least one collagen receiving structure selected from the group consisting of at least one tunnel disposed through the anchor body or an external surface feature of the anchor body. The anchor further comprises at least one hair strand projecting from a distal end of the anchor body and alternatively wherein the at least one hair strand includes a bend, wherein the at least one collagen receiving structure, or the external surface feature, is configured to support collagen ligature growth after subcutaneous implantation of the hair implant so as to anchor the hair implant in the recipient. The hair implant includes a two-part construction having a base module formed of the anchor body and at least one hair stem configured for coupling with a long hair strand. Another hair implant alternative includes a hair strand having a first end that is passed through the skin, underneath and the up through the skin at another location to result in the hair strand having two portions projecting from the skin surface.

A hair implant includes: (a) a hair strand anchor including: an anchor body; at least one hair chamber disposed within the anchor body; and at least one tunnel through the anchor body, where the tunnel is free of a hair; and (b) at least one hair strand having a portion thereof retained in the at least one of the hair chamber; wherein the tunnel is configured to support collagen ligature growth after subcutaneous implantation by receiving and retaining collagen ligatures that anchor the hair implant to a hair implant recipient. Also disclosed is a hair implant including an anchor with first and second anchor bodies and at least one bridge connecting the anchor bodies and bridging at least one void between the anchor bodies, wherein the bridge supports and retains collagen ligature growth. One-piece implants are also disclosed, as are anchors, hair restoration and manufacturing methods.

A prosthesis for repairing a hernia defect includes a patch body, a hoisting frame releasably attachable to the patch body, and a tether attached to the hoisting frame with a free end extendable through the thickness of the patch body and accessible from the side of the patch body opposite to where the hoisting frame is releasably attached. The patch body and/or the hoisting frame includes a self-expanding support member. The hoisting frame includes a frame body with an outer frame component and a force translation component for directing pulling forces on the tether across the frame body. The outer frame component has a loop configuration to generally follow the patch periphery with overlapping end portions or a gap between free ends thereof. The force translation component is separable into multiple segments to facilitate withdrawal of the hoisting frame through an opening when released from the patch.

The present teachings provide a device to change the pressure in a chamber of a heart and methods of making and using thereof. One aspect of the present teachings provides a device comprising a frame (for example, a metallic frame) and a scaffold. The frame of the device has a distal flange portion, a shunt portion, and a proximal flange portion. The distal and proximal flange portions can align with the shunt portion and form an elongated first profile. At least one of the distal and proximal flange portions can bend radially away from the shunt portion to form a flange like profile. The scaffold includes one or more than covering layers and encloses parts of the frame or the entire frame. The covering layer provides a barrier between the biological matter and the frame of the device. The scaffold is designed to control and direct tissue growth, for example, by stimulating an irritation response and inducing cell proliferation around the retention flange and/or discouraging cell proliferation inside the shunt portion.

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.