An analytical assembly within a unified device structure for integration into an analytical system. The analytical assembly is scalable and includes a plurality of analytical devices, each of which includes a reaction cell, an optical sensor, and at least one optical element positioned in optical communication with both the reaction cell and the sensor and which delivers optical signals from the cell to the sensor. Additional elements are optionally integrated into the analytical assembly. Methods for forming and operating the analytical system are also disclosed.

Devices and methods that measure one or more properties of a living cell culture that is contained in liquid media within a vessel, and typically analyzes plural cell cultures contained in plural vessels such as the wells of a multiwell microplate substantially in parallel. The devices incorporate a sensor that remains in equilibrium with, e.g., remains submerged within, the liquid cell media during the performance of a measurement and during addition of one or more cell affecting fluids such as solutions of potential drug compounds.

The SACOS apparatus solves counterfeiting issues instantaneously and develops new security features in order to improve the role that international regulatory commissions, governments, and central banks play to effectively fight counterfeiting.

A method and an arrangement, for detecting microorganisms on a surface are disclosed. At least a portion of the surface is covered with a sensor foil in an airtight manner. An oxygen-permeable layer of the sensor foil is doped with an oxygen indicator dye, loaded with oxygen and faces the at least one portion of the surface. An excitation light passes through an oxygen-impermeable at least partially transparent read-out carrier layer of the foil to the dye in the oxygen-permeable layer which is then excited by the excitation light. An emission of the oxygen indicator dye) transmitted through the carrier layer is detected by a detection element over or after a period of time (t). The emission of the oxygen indicator dye from the oxygen-permeable layer is indicative of the amount of oxygen consumed by microorganisms from the oxygen-permeable layer covering the at least one portion of the surface.

System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.

Embodiments herein relate to optoelectronic interfaces for multimode analyte sensors for use with implantable medical devices. In an embodiment, an implantable medical device is included. The implantable medical device can include a first chemical sensor including an optical excitation assembly comprising a first visible spectrum emitter, a second visible spectrum emitter, and at least one of a near-infrared (NIR) emitter and an ultraviolet emitter. The first chemical sensor can also include an optical detection assembly including a colorimetric response detector, and a photoluminescent response detector. The first chemical sensor can also include a multimode sensing element including a colorimetric response element specific for a first chemical analyte, a photoluminescent response element specific for a second chemical analyte. Other embodiments are also included herein.

A sensor element for an optochemical sensor includes: a luminescence indicator, whose luminescence can be quenched with oxygen; and scavenger units to deactivate singlet oxygen, forming a chemical reaction product by reacting with singlet oxygen, wherein the scavenger units are selected to be recovered by a decomposition reaction induced thermally, photochemically or by a pressure increase of the chemical reaction product formed by the reaction with singlet oxygen.

A system for analysis of a fluid sample has a carrier with a channel. A plug with a sensor can be inserted into a socket arranged on the carrier in such a way that the sensor is in contact with an interior volume of the channel. The sensor can be an optical sensor, in particular based on fluorescence. Optical fibres may be connected to the plug. A camera (8) may be provided to record an image of the plug. The carrier may in particular be a microfluidic chip and the channel a microfluidic channel.

The present disclosure relates to an electrochemical sensor for determining a measurand correlating with a concentration of an analyte in a measuring fluid, comprising: a sensor membrane designed to be in contact with the measuring fluid for detecting measured values of the measurand; a probe housing which has at least one immersion region designed for immersion into the measuring fluid, wherein the sensor membrane is arranged in the immersion region of the probe housing; and a measurement circuit which is at least partially contained in the probe housing and is designed to generate and output a measurement signal dependent on the measurand, wherein the sensor membrane contains an optically detectable substance for marking the sensor membrane.

The present disclosure relates to a sensor cap for an optochemical sensor for determining or monitoring at least one analyte present in a medium having a substantially cylindrical plug-in component and a sleeve-shaped outer component. The plug-in component has an optical component with a convex-shaped surface region for optimal flow, and the optical component at least partially consists of a material transparent to measuring radiation. On the surface region of the optical component is an analyte-sensitive matrix having at least one functional layer. The plug-in component and the sleeve-shaped component are designed such that the connecting region coming into contact with the medium is between the plug-in component and the sleeve-shaped outer component in the edge region of the optical component or is at a radial distance from the edge region of the optical component, and is sealed, without a gap, facing the medium.