[Problem to be Solved by the Invention] The purpose of the present invention is to provide a competitive immunochromatographic analysis method and immunochromatographic sensor using said analysis method capable of intuitively displaying a molecular concentration of a substance to be measured and facilitating visual judgement of the molecular concentration. [Problem to be Solved by the Invention] Competitive immunochromatographic analysis method according to the present invention is characterized in that the method comprises a step for supplying a mixed solution, in which a test solution containing a substance to be measured A and a labeled antibody B are mixed, to one or more judgement parts wherein said judgement parts are formed by immobilizing a text antibody C which specifically reacts with the labeled antibody B specifically reacting with the substance to be measured A on a membrane carrier in the form of character(s) or figure(s) and immobilizing a mask antigen D composed of the same antigen as the substance to be measured A on the membrane carrier so as to surround said text antibody C, a step for competitively binding the labeled antibody B to the substance to be measured A, the mask antigen D and the text antibody C on the judgement parts, a step for judging the concentration of the substance to be measured A based on the signal from the labeled antibody B bound to the text antibody C and the mask antigen D.

The invention is directed to a synthetic particle antibody comprising a bi-functional particle framework, such as for example and not limitation, a Janus micro- or nanoparticle, wherein one side of the bi-functional particle comprises targeting ligands (such as for example and not limitation, a protein, a peptide, an aptamer, and/or fragments thereof, wherein the at least one targeting ligand has the ability to specifically bind to a desired cell or tissue type in a subject's body) and the other side of the bi-functional particle comprises immune-activating ligands (such as for example and not limitation, fragments of the Fc portion of antibodies, immune-activating peptides, immune-activating aptamers, and other proteins, peptides or nucleic acids that mimic the structure and/or function of the Fc portion of antibodies).

The invention is directed to a synthetic particle antibody comprising a bi-functional particle framework, such as for example and not limitation, a Janus micro- or nanoparticle, wherein one side of the bi-functional particle comprises targeting ligands (such as for example and not limitation, a protein, a peptide, an aptamer, and/or fragments thereof, wherein the at least one targeting ligand has the ability to specifically bind to a desired cell or tissue type in a subject's body) and the other side of the bi-functional particle comprises immune-activating ligands (such as for example and not limitation, fragments of the Fc portion of antibodies, immune-activating peptides, immune-activating aptamers, and other proteins, peptides or nucleic acids that mimic the structure and/or function of the Fc portion of antibodies).

A microfluidic Western blot method and system including a microfluidic western blot method for immunoassay of proteins, the method including introducing a sample including the proteins onto a chip; electrophoretically separating the proteins; binding the separated proteins to beads to form protein-attached beads, the beads being magnetic; flowing the protein-attached beads into a magnetic holding region; applying a magnetic field to the magnetic holding region to fix the protein-attached beads in place within the magnetic holding region; binding primary antibodies to target proteins on the protein-attached beads; binding secondary antibodies to the bound primary antibodies; and detecting the bound secondary antibodies.

A microfluidic Western blot method and system including a microfluidic western blot method for immunoassay of proteins, the method including introducing a sample including the proteins onto a chip; electrophoretically separating the proteins; binding the separated proteins to beads to form protein-attached beads, the beads being magnetic; flowing the protein-attached beads into a magnetic holding region; applying a magnetic field to the magnetic holding region to fix the protein-attached beads in place within the magnetic holding region; binding primary antibodies to target proteins on the protein-attached beads; binding secondary antibodies to the bound primary antibodies; and detecting the bound secondary antibodies.

Systems and apparatus for performing analysis of human biological samples are described. Collected biological samples are combined with a substance including nucleic acid complexes and the combined substance is processed using gel electrophoresis. An indication of a detected compound in the biological sample and/or a particular medical condition associated with the detected compound is output from the apparatus.

Systems and apparatus for performing analysis of human biological samples are described. Collected biological samples are combined with a substance including nucleic acid complexes and the combined substance is processed using gel electrophoresis. An indication of a detected compound in the biological sample and/or a particular medical condition associated with the detected compound is output from the apparatus.

The present invention relates to polymeric membranes. In particular, the present invention relates to the use of membranes comprising polyvinyl alcohol in electrophoresis.

The present invention relates to polymeric membranes. In particular, the present invention relates to the use of membranes comprising polyvinyl alcohol in electrophoresis.

A nanoscale protein-sensing platform with a non-equilibrium on-off switch that employs dielectrophoretic and hydrodynamic shear forces to overcome these thermodynamic limitations with irreversible kinetics. The detection sensitivity is achieved with complete association of the antibody-antigen-antibody (Ab-Ag-Ab) complex by precisely and rapidly assembling carbon nanotubes (CNT) across two parallel electrodes via sequential DC electrophoresis and dielectrophoresis (DEP), and with single-CNT electron tunneling conductance. The high selectivity is achieved with a critical hydrodynamic shear rate between the activated dissociation shear rates of target and non-target linkers of the aligned CNTs.