A method includes estimating a value of a parameter indicative of an age or lifespan of a population of red blood cells of a subject, estimating a value of average glucose (AG) of the subject based on (i) the value of the parameter and (ii) a value indicative of an amount of glycated hemoglobin (HbA1c) of the subject, and providing information for treatment or diagnosis of a hyperglycemia condition of the subject based on the estimated value of AG.

Provided is a biological substance detection sensor used in an electrochemical measurement method and allowing high-precision measurement by reducing a blank current. A biological substance detection sensor of the present invention for analyzing a component in a testing solution using a mediator includes at least: an insulating substrate; a conductive part formed on a surface of the insulating substrate and including at least one pair of a working electrode and a counter electrode; and a reagent part disposed in contact with or in a vicinity of the conductive part and including at least one of protein and the mediator. The reagent part further includes at least one additive selected from the group consisting of a halide and/or a pseudo halide.

An in-vitro medical diagnostic system includes a host (1), a removable test card (2) and a removable reagent pack (3). The reagent pack (3) includes a calibrating liquid needed in a process for calibrating the test card (2); the reagent pack (3) is clamped to the host (1), with only first power drive and valve control transmission being provided between the host (1) and the reagent pack (3); and the test card (2) is mounted on the host (1) during the entire test process, with only second power drive and an optical conduction path being provided between the host (1) and the test card (2). No liquid path is present in the host (1) of the in-vitro diagnostic system, thus eliminating hidden medical dangers. Tests for blood gas, hemoglobin and derivatives thereof can be achieved in a single test card.

A method includes estimating a value of a parameter indicative of an age or lifespan of a population of red blood cells of a subject, estimating a value of average glucose (AG) of the subject based on (i) the value of the parameter and (ii) a value indicative of an amount of glycated hemoglobin (HbA1c) of the subject, and providing information for treatment or diagnosis of a hyperglycemia condition of the subject based on the estimated value of AG.

Described herein are devices, systems, and methods used to measure glycated hemoglobin.

The invention relates to a method for detecting an analyte present in a liquid specimen, characterized in that it comprises steps of: injecting said liquid specimen into a detection chamber (23), said detection chamber (23) having a non-zero volume enclosing polymeric beads (25) covered with a reagent suitable for said analyte to be detected, capturing at least one image of at least one region of the detection chamber using a sensor (30), processing said image acquired by the sensor, this comprising determining a texture level of said acquired image, and determining a concentration of said analyte depending on the texture level determined for said image.

This invention relates to the measurement of hemoglobin in the blood. Previously, chemical interference from medications, other blood components, and incomplete reagent rehydration can impact the accuracy and prolong the reaction time required to determine total hemoglobin in blood. Embodiments of the present invention use a disposable body is housed within the capillary channel and adapted to receive a flow of blood from the entrance such that air in the disposable body is pushed out through a vent. A measurement system is configured to measure a property of the flow of blood. That property can be correlated to total hemoglobin count.

A hemoglobin detecting method is executed by a mobile device having a hemoglobin detecting function. The mobile device includes a processor unit, a first light source that generates a first light beam, and a light detecting module that receives a second light beam that is generated when the first light beam travels through an analyte solution and is reflected. The light detecting module generates first to fourth intensity signals according to the second light beam, and the processor unit determines whether the absorption spectrum of the analyte solution matches a target spectrum. If the absorption spectrum of the analyte solution matches the target spectrum, the processor unit generates positive result information; otherwise, the processor unit generates negative result information. The mobile device provides a fast and accurate way to detect blood in a stool solution, which does not require collecting samples of stool or applying any chemical.

The present disclosure is directed to a thin-film element that enables analytes to be analyzed on separate surfaces. In an example, a thin-film element includes a first layer for processing a fluid sample to generate a first analyte and a second analyte. The thin-film element also includes a second layer configured to be impermeable to the first analyte to enable the first analyte to be retained by the first layer and permeable to the second analyte to enable the second analyte to pass through the second layer. The thin-film element further includes a third layer configured to retain the second analyte. The second layer includes a first reflective surface and a second reflective surface to provide reflectance signals indicative of analytes present in the first and third layers to sensors located on opposite sides of the thin-film element.

A test apparatus and method for measuring a concentration of a target by correcting for an impact of hemoglobin are provided. The target measurement method includes measuring an absorbance of hemoglobin in a sample, measuring an absorbance of a target in the sample, determining variation of the absorbance of the target according to the measured absorbance of the hemoglobin, and correcting the absorbance of the target by subtracting the determined variation of the absorbance of the target from the measured absorbance of the target.