To provide a composition in which fine particles of solid lipid such as ceramides are emulsified and dispersed in a stable manner without being crystalized. A dispersion of fine lipid particles containing the following components (A) to (E), wherein the dispersion has a pH of 3.5 or more and 8.0 or less and the fine lipid particles have a heat of fusion of 0.30 J/g or less in a temperature range of 45° C. or more and 80° C. or less and an average particle size of less than 200 nm. (A) one or more selected from the group consisting of a sterol and a derivative thereof, (B) a lipid other than the component (A), the lipid being solid or semi-solid at 25° C., (C) an anionic surfactant, (D) a water-soluble solvent and (E) water.

Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy/radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.

A three-part method of cleaning a user's teeth and/or gums is disclosed. First, a user applies a tonic of essential oils to the user's teeth and/or gums by either brushing, rubbing, rinsing and/or flossing with the tonic thereby destroying harmful bacteria. Second, the user brushes with a toothpaste having nano-hydroxyapatite being particles of 50 nanometers or smaller. The nano-hydroxyapatite is absorbed into the surface opening inside dentinal tubules of the teeth. Third, the user seeds their mouth with an oral probiotic having beneficial bacteria. The third step must come after both the first and second steps.

The present invention relates to pre-formulations comprising low viscosity, non-liquid crystalline, mixtures of: a) at least one neutral diacyl lipid and/or at least one tocopherol; b) at least one phospholipid; c) at least one biocompatible, oxygen containing, low viscosity organic solvent;
wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The preformulations are suitable for generating parenteral, non-parenteral and topical depot compositions for sustained release of active agents. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament.

Methods and aqueous compositions for styling or reshaping keratinous fibers such as human hair are provided. An aqueous styling composition includes (a) 0.5 to 15.0% by weight of at least one disaccharide; and (b) 0.01 to 20.0% by weight of at least one alkali salt and/or alkaline earth salt, wherein the composition is free of synthetic film-forming polymers.

A method for producing a powder solid composition including a base containing non-volatile liquid oil, the method includes: blending wax in a powder form into the base; dispersing the base in a solvent; volatilizing the solvent at a first temperature where the wax does not dissolve; and heating the base at a second temperature where the wax dissolves, wherein a blending amount of the non-volatile liquid oil is 15% by mass or more and 40% by mass or less with respect to the base.

The present specification discloses compositions comprising one or more encapsulates comprising one or more agents and methods and uses for the disclosed agents. A composition disclosed herein can be incorporated into a body wash, an after shower body lotion, a shampoo, a conditioner, a soap, a gel, a hand sanitizer, a cream, a spray, a mouse, a lotion, an ointment, a make-up product, a lip balm, a hair spray product, an arachnid/insect repellent or a medicinal product.

The presently disclosed subject matter relates to a system for customizing a cosmetic product. The system includes: an interface device, in electronic communication with a single batch formulation device. The single batch formulation device is configured to formulate a customized cosmetic product, and a threaded container configured to be imported into the single batch formulation device containing a base and exported from the single batch formulation device containing the customized cosmetic.

A cosmetic composition includes: (i) one or more vegetable butters in an amount of from 5 to 35% by weight of the total composition; (ii) one or more vegetable oils in an amount of from 20 to 50% by weight of the total composition; and (iii) starch in an amount of from 40 to 85% by weight of the total composition. The cosmetic composition is free from preservatives as defined herein.

A chemical-free, body cleansing cream formulation is provided comprising organic Aloe vera gel, coconut oil, sunflower oil, shea butter, witch hazel, one or more essential oils such as clary sage or distilled lime, and one or more pH-balancing agents such as apple cider vinegar or citric acid. The formulation is a natural alternative to soap which does not include chemicals such as sodium hydroxide. The cleansing cream has no soapsuds and produces no foam, and yet can still cleanse the most intimate areas of the body with very little to no risk of skin irritation. Alternatively, the cream or formulation can include Tribulus, witch hazel, horny goat weed (Epimedium), shea butter, ginseng, citric acid, coconut oil, almond oil, and flaxseed.