The purpose of the present invention is to provide a substrate for a biochip, a biochip, a method for manufacturing a biochip, and a method for preserving a biochip. The present invention pertains to a biochip having: a substrate having a hydrophilic reaction area; and a spot for a substance to be fixed that includes a biomaterial, the spot being disposed in the reaction area; the reaction area being enclosed by boundaries capable of retaining a liquid on the inner sides, and the spot furthermore including a thickening agent and/or a surfactant. The present invention also pertains to a method for manufacturing said biochip.

Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication. Uses of a Molecular Net may include analyte capture, analyte enrichment, analyte purification, analyte detection, analyte measurement and analyte delivery. Molecular Nets may be used in liquid phase or on solid phases such as nanomaterials, modified metal surfaces, nanospheres, microspheres, microtiter plates, slides, pipettes, cassettes, cartridges, discs, probes, lateral flow devices, microfluidics devices, microfluidics devices, optical fibers and others.

Disclosed is a covalently-linked multilayered three-dimensional matrix comprising capture molecules, linkers and spacers (referred to as a Molecular Net) for specific and sensitive analyte capture from a sample. Also disclosed herein is a Molecular Net comprising covalently-linked multilayered three-dimensional matrix comprising more than one type of capture molecule and more than one type of linker and may comprise one or more spacer for specific and sensitive capture of more than one type of analyte from a sample. A Molecular Net may comprise a pseudorandom nature. Use of various capture molecules, linkers and spacers in a Molecular Net may confer unique binding properties to a Molecular Net. Porosity, binding affinity, size exclusion abilities, filtration abilities, concentration abilities and signal amplification abilities of a Molecular Net may be varied and depend on the nature of components used in its fabrication. Uses of a Molecular Net may include analyte capture, analyte enrichment, analyte purification, analyte detection, analyte measurement and analyte delivery. Molecular Nets may be used in liquid phase or on solid phases such as nanomaterials, modified metal surfaces, nanospheres, microspheres, microtiter plates, slides, pipettes, cassettes, cartridges, discs, probes, lateral flow devices, microfluidics devices, microfluidics devices, optical fibers and others.

The present invention is related to a parallel line biochip for multiplex diagnosis. The parallel line biochip for multiplex diagnosis includes a plurality of line strips disposed in parallel, and a well configured to immobilize the line strips. Since the parallel line biochip for multiplex diagnosis can be used to connect two or more line strips in parallel, the parallel line biochip for multiplex diagnosis has an effect of measuring various materials present in a biological test sample at the same time.

The present invention is related to a parallel line biochip for multiplex diagnosis. The parallel line biochip for multiplex diagnosis includes a plurality of line strips disposed in parallel, and a well configured to immobilize the line strips. Since the parallel line biochip for multiplex diagnosis can be used to connect two or more line strips in parallel, the parallel line biochip for multiplex diagnosis has an effect of measuring various materials present in a biological test sample at the same time.

Solar energy device comprising at least one of a photovoltaic cell or a solar thermal collector having an absorption bandwidth in the infrared wavelength region of the solar spectrum; a visible light-transmitting reflector; and at least one of a graphic film or lighted display. The graphic film or a lighted display present is visible through the visible light-transmitting reflector. The solar energy devices can be used, for example, as a sign (e.g., an advertising sign or a traffic sign), on the side and/or roof, as well as in a window, of a building.

Solar energy device comprising at least one of a photovoltaic cell or a solar thermal collector having an absorption bandwidth in the infrared wavelength region of the solar spectrum; a visible light-transmitting reflector; and at least one of a graphic film or lighted display. The graphic film or a lighted display present is visible through the visible light-transmitting reflector. The solar energy devices can be used, for example, as a sign (e.g., an advertising sign or a traffic sign), on the side and/or roof, as well as in a window, of a building.

In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.

In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.

Hybrid microparticle having a polymer core and a shell which surrounds the polymer core at least in sections and which has a silicon dioxide layer; characterized by an RF value, the RF value being defined as the ratio of an external surface area amenable to the adsorption of nitrogen to a surface area which is computable from an arithmetic mean diameter of the hybrid microparticle considered as an ideal sphere, where the shell has a structure selected from: closed and smooth, with the shell having an RF value of between 1 and 1.5; closed and hillocky, with the shell having an RF value of between 1.51 and 3; or open, with the shell having an RF value of greater than 3.01.