Disclosed are methods for inhibiting the progression of neurodegenerative disease. The methods include administering to a patient suffering from such a disease a composition comprising deuterated arachidonic acid or an ester thereof.

An analytical process for detecting antibody in human blood serum, which antibody is directed against blood group antigen, wherein the serum contains an additional antibody directed against a surface antigen, by contacting the serum to be analysed with blood cell membranes, which naturally bear surface blood group antigens, followed by detection of agglutination which indicated the presence of antibody directed against at least one surface antigen of the blood cell membranes. The agglutination reaction caused by the additional antibody is prevented, allowing the detection of anti-blood group antibody.

A method for incubating reagents, suspensions and/or biological products to a predetermined temperature for biological testing; the method comprising the steps of: a) providing a selected biological product in a receptacle and which is required to be incubated to a temperature which simulates a natural thermal environment of the biological product; b) applying controlled heating to or near the biological product using at least one laser emitting from a laser source for a time sufficient to reach a target temperature or which simulates a target temperature of the natural thermal environment in which the biological product exists.

A method for incubating reagents, suspensions and/or biological products to a predetermined temperature for biological testing; the method comprising the steps of: a) providing a selected biological product in a receptacle and which is required to be incubated to a temperature which simulates a natural thermal environment of the biological product; b) applying controlled heating to or near the biological product using at least one laser emitting from a laser source for a time sufficient to reach a target temperature or which simulates a target temperature of the natural thermal environment in which the biological product exists.

A diagnostic biological array, for determining quantitative and measurable blood quality and/or maximum storage period of a blood unit at the day of donation and/or survivability period (after transfusion) of 75% of the RBCs of an individual blood unit and/or comparing a blood unit quality level to the recipient blood quality prior to transfusion and/or detecting impact on blood flow and correlation to specific diseases, by using parameters which are correlated to the red blood cell flow properties (FP).

A diagnostic biological array, for determining quantitative and measurable blood quality and/or maximum storage period of a blood unit at the day of donation and/or survivability period (after transfusion) of 75% of the RBCs of an individual blood unit and/or comparing a blood unit quality level to the recipient blood quality prior to transfusion and/or detecting impact on blood flow and correlation to specific diseases, by using parameters which are correlated to the red blood cell flow properties (FP).

Provided herein are methods for determining the T cell receptor affinity and sequence of antigen-specific T cells using a micropipette adhesion assay and single cell paired TCR/TCR sequencing. Further provided are methods for the treatment of viral infections or cancers by adoptive transfer of high affinity functional T cells.

The systems and methods contained herein are directed toward automated analysis of agglutination reactions to determine properties of materials, including viruses and vaccines thereto. Advanced digital imaging and processing techniques are used to determine the presence or absence of viruses or antibodies within a fluid sample. The systems and methods are versatile, and can be used to determine specific properties of biomaterials and viruses, such as titer value, concentration, genotype, phenotype, serotype, vaccine efficacy, viral resistance and other properties of relevance in the medical, research and development fields. Also provided are systems and methods of standardization, repeatability, and data storage and transmittal to reduce errors and subjectivity inherent to conventional assays characterized by human readers.

The systems and methods contained herein are directed toward automated analysis of agglutination reactions to determine properties of materials, including viruses and vaccines thereto. Advanced digital imaging and processing techniques are used to determine the presence or absence of viruses or antibodies within a fluid sample. The systems and methods are versatile, and can be used to determine specific properties of biomaterials and viruses, such as titer value, concentration, genotype, phenotype, serotype, vaccine efficacy, viral resistance and other properties of relevance in the medical, research and development fields. Also provided are systems and methods of standardization, repeatability, and data storage and transmittal to reduce errors and subjectivity inherent to conventional assays characterized by human readers.

The present invention provides novel methods for the detection of antibodies, in particular, blood group antibodies. The methods of this invention may be applied to pre-transfusion blood compatibility testing for the detection of incompatibility between donor units (comprising donor red blood cells (erythrocytes)) and a recipient.