G01N33/54388

Electric, magnetic, and RF sensor based methods to register and interpret lateral flow assay measurements
11493511 · 2022-11-08 ·

A system, apparatus, and method for registering and interpreting the results of lateral flow assay determination by using electric, magnetic, and RF sensors incorporated within the test strip, attached to the inside of the enclosure for same and/or contained in a test fixture; instead of relying on optical inspection techniques. This method features high reliability, low cost, and ability for quantitative and dynamic measurements.

METHOD, SYSTEM AND APPARATUS FOR SUBSTANCE IDENTIFICATION
20230101980 · 2023-03-30 · ·

This disclosure generally relates to embodiments for detecting presence of one or more allergens in mammalian milk. An exemplary embodiment relates to a method to detect presence of one or more allergen molecules in a composition of mammalian milk, the method includes the steps of: providing a substrate having a plurality of detection sites thereon, each of the plurality of detection sites configured to detect presence of one or more allergen molecules; exposing the plurality of detection sites to a quantity of mammalian milk; detecting presence of a first allergen molecule at a first of the plurality of detection sites by detecting a fragment of DNA, RNA, or amino acids corresponding to the first allergen molecule; wherein the detected fragment excludes naturally occurring molecules present in the composition of mammalian milk.

System for evaluating urine for the presence or absence of pregnanediol glucuronide and other hormones and analytes
11573225 · 2023-02-07 · ·

Various aspects of the system and methods described herein rely upon the operation of lateral flow assays specially configured to evaluate a bodily fluid for at least the presence or absence of pregnanediol glucuronide at a threshold selected from the range inclusive of 1 μg/mL-10 μg/mL. The results from the lateral flow assays are optionally interpreted in association with an application operating upon a mobile device or a system for the collection, interpretation and storage of results. The interpretations are useful in accordance with facilitating diagnoses and treatments associated with medical conditions related to the generated interpretations of the lateral flow assays.

Method and device for detecting pyrethroid pesticide residues in crops

A method and device for detecting pyrethroid pesticide residues in crops. Reaction membrane is arranged on a bottom plate and provided with a check-up line and a quality control line; a first mounting block and a second mounting block are arranged on the bottom plate; a first slide is arranged in the first mounting block, a second slide is arranged in the second mounting block; a sample pad and a bonding pad are arranged in the first slide; a water absorption pad is arranged in the second slide; a liquid inlet provided with a pipe is formed in the first mounting block, a pressing hole provided with a press block is formed in the second mounting block; protrusions are respectively formed on the pipe and the press block; sliding grooves are formed in the liquid inlet and the pressing hole; and first springs are arranged between the protrusions and the sliding grooves.

DEVICES AND METHODS FOR LATERAL FLOW TESTS OF BODILY FLUIDS

The disclosed devices for lateral flow testing may include a receptacle for receiving bodily fluids from a patient that has a predetermined fluid volume for application to one or more lateral flow test strips. A test strip holder may be positioned to receive the predetermined fluid volume of the bodily fluids from the receptacle. Various other components, devices, and methods are also disclosed.

ELECTROCHEMICAL LATERAL FLOW IMMUNOLOGICAL TEST METHOD, SENSOR FOR SAME, AND METHOD FOR MANUFACTURING SAME
20230030862 · 2023-02-02 ·

In an electrochemical lateral flow immunological test method, flow of a sample solution is controlled. As a result, the reaction time is short and quantitative measurements and electrical measurements can be performed with excellent sensitivity and high accuracy, and the invention provides a sensor employed in the method. Electrode portions, electrically conductive portions for transferring electric current from the electrode portions, and connecting portions connected to an electrical measuring instrument for measuring the electric current values are arranged on a supporting body including a resin sheet, pads and the like disposed by partial lamination on the supporting body. A sample solution flows over the plurality of pads, and electrochemical detection is performed by controlling the flow at the position of the electrode portions. Furthermore, the flow is controlled by a flow rate control pad, a flow passage portion fiber pad, and flow rate control protruding portions.

DEVICE FOR PERFORMING AN ENZYME-BASED DIAGNOSTIC TEST AND METHODS FOR USE THEREOF
20230095831 · 2023-03-30 ·

Enzyme-based diagnostic testing systems for detecting and quantifying at least one of the activity level or the concentration of an enzyme or a biochemical analyte in a biological sample. Such enzyme-based diagnostic testing systems can provide rapid, accurate, affordable laboratory-quality testing at the point of care. An enzyme-based diagnostic testing system may include a lateral-flow chromatographic assay cassette that is configured for assaying an amount or activity of an enzyme in a sample or for enzymatically determining the concentration of an enzyme substrate in a sample. Additionally, the enzyme-based diagnostic testing systems may include testing devices (e.g., a smartphone or a similar remote computing device) having data collection and data analysis capabilities. Such testing devices may also include automated data reporting and decision support.

SIMPLE DISEASE DIAGNOSIS TOOL
20230032700 · 2023-02-02 ·

Proposed is a simple disease diagnosis tool including a base plate made of a material that is hydrophilic and spreads water sufficiently, and pattern display panels made of a material that is also hydrophilic and spreads water sufficiently and each adhered to one side surface of the base plate, wherein a reagent is applied to one side of the base plate, and wherein the pattern display panels include a plurality of disease test display portions each configured to have one end in contact with the reagent of the base plate or to be spaced apart from the reagent of the base plate by predetermined intervals, and diagnosis checking lines each marked to surround the outside of the disease test display portions while being spaced apart from the disease test display portions at predetermined intervals.

SAMPLE TEST CASSETTE AND ANALYTE TEST SYSTEM UTILIZING THE SAME

A sample test cassette includes an inlet configured to introduce a sample liquid into the sample test cassette; an elongate channel configured to receive an elongate lateral flow test strip and configured with a first end that is configured to be in liquid communication with the inlet; and a mechanical transport system that is an integral part of the sample test cassette and is configured to generate a flow of the sample liquid from outside of the inlet and towards the first end of the elongate channel.

Detection of waterborne pathogens with paper strips
20220348978 · 2022-11-03 ·

The disclosure provides methods and apparatuses to test for E. coli in liquid samples. The apparatus includes a paper strip having a hydrophobic area at one end and a reaction area at the other end.