Methods of preparing a drug for delivery and drug delivery systems for achieving the same are disclosed. A method of preparing a drug for delivery may include providing a diluent contained in a diluent container and providing a drug product contained within a drug product container. The method may further include fluidly connecting the diluent container and the drug product container. Additionally the method may include urging, via a pump, at least a portion of the diluent from the diluent container into the drug product container to at least partially reconstitute the drug product.

Methods for setting up, maintaining and operating a radiopharmaceutical infusion system, that includes a radioisotope generator, are facilitated by a computer of the system. The computer may include pre-programmed instructions and a computer interface, for interaction with a user of the system, for example, in order to track contained volumes of eluant and/or eluate, and/or to track time from completion of an elution performed by the system, and/or to calculate one or more system and/or injection parameters for quality control, and/or to perform purges of the system, and/or to facilitate diagnostic imaging.

Apparatus and methods for monitoring and delivering a cell suspension. In certain examples, the apparatus comprises a reservoir containing the cell suspension, a cannula, and a liquid transfer mechanism configured to transfer the cell suspension from the reservoir to the cannula. The apparatus can also comprise an agitation mechanism to agitate the cell suspension, and a monitoring device to quantify a concentration of cells transferred from the reservoir to the cannula.

A drug solution administration unit including a drug solution administration module having a first flow path unit, a second flow path unit, and a drive mechanism unit, and a drug solution administration device having a branch path and a main path. The first flow path unit includes an upstream side main body where a first flow path to store drive solution is formed, and the second flow path unit includes a downstream side main body where a second flow path to store drug solution is formed. The drive mechanism unit includes a pair of electrodes and a porous body sandwiched between the pair of electrodes, the drive mechanism unit has a connecting flow path connecting a downstream end of the first flow path and an upstream end of the second flow path.

In some embodiments, a system can include a fluid delivery assembly and a drive assembly. The fluid delivery assembly is configured to be releasably mechanically and, optionally, electrically coupled to the drive assembly. When the fluid delivery assembly is releasably coupled to the drive assembly, the drive assembly can control delivery of fluid from the fluid delivery assembly (e.g., to a patient). For example, the drive assembly can be releasably coupled to the fluid delivery assembly to control delivery of fluid from the fluid delivery assembly to provide continuous (e.g., non-pulsatile) fluid flow from the fluid delivery assembly.

Disclosed are methods of radioisotope infusion comprising infusing saline comprising a diagnostic dose of a radioisotope, and delivering a pre-measured volume of push saline. The disclosed methods confer improved image quality with low background noise, higher signal to noise ratio (SNR) and higher contrast to noise ratio (CNR), leading to better diagnosis and thus eliminating the need of repeating the infusion and imaging which in turn reduces exposure of a patient to radiation.

In some embodiments, a medical fluid connector is configured to receive an emitter of therapeutic agents to be emitted into a fluid pathway within the connector, the medical fluid connector comprising a proximal female end, an intermediate region, a distal male end, and a fluid pathway extending from the proximal female end, through the intermediate region, to the distal male end. A retaining structure is positioned within the intermediate region. The retaining structure is configured to securely receive an emitter of one or more therapeutic agents in a position and orientation where the fluid pathway is configured to convey fluid moving longitudinally through the fluid pathway directly into a proximal region of the emitter, around one or more lateral surfaces of the emitter, and toward the distal male end.

The present embodiments provide apparatus and methods suitable for delivering a therapeutic agent to a target site. The apparatus generally comprises at least one container for holding a therapeutic agent, and a pressure source for facilitating delivery of the therapeutic agent. In one embodiment, the pressure source may be placed in selective fluid communication with a proximal region of the container and fluid from the pressure source may flow through at least a portion of the container to urge the therapeutic agent through container towards the target site. In an alternative embodiment, the container and the pressure source may be coupled to first and second inlet ports of a connecting member, respectively, such that the therapeutic agent flows through an outlet port of the connecting member and towards the target site.

A medical fluid system includes a container holding a fluid at a level; and a radio frequency level sensor operably connected to the container and including an emitting electrode and a receiving electrode, the electrodes operating as a transmission line having an electrical impedance that varies with the level or volume of the fluid in the container, the level sensor configured to measure a phase shift of the transmission line, the phase shift indicative of the level or volume of the fluid in the container.

A multi-chamber syringe for delivering a plurality of fluids to a central venous catheter includes a barrel and a plunger. The barrel includes a plurality of chambers, and a first one of the plurality of chambers has a predefined volume of a saline flush stored therein. Actuation of the plunger causes the predefined volume of the saline flush to be dispensed from the barrel into the central venous catheter.